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The map label for this gene is clcA [H]

Identifier: 238924204

GI number: 238924204

Start: 1724821

End: 1726092

Strand: Direct

Name: clcA [H]

Synonym: EUBREC_1842

Alternate gene names: 238924204

Gene position: 1724821-1726092 (Clockwise)

Preceding gene: 238924203

Following gene: 238924213

Centisome position: 50.0

GC content: 44.73

Gene sequence:

>1272_bases
ATGAATGAAACAACCAGGCAATTGATTGTGCATAAGGTAAAGCATAATACGAAACGCCTTATAACATCCATTAAATGGGT
AATCTTTTCTATCGTTGTCGGCATAGTCGCAGGAAGCTGCGGCACCGCATTTTATTTTGCCCTGTCGGTCGTAACCGATT
TCAGAATGAAATACCCTTGGCTCATTTACTTTCTGCCAATCGGCGGACTTGCCATTGTAGGACTCTATCATCTGTGTAAA
GACGATAACGACACCGGAACCAATCTGGTAATATCAGCTATCCATTCAGGCGACAAGGTGCCCTTTATAATGGCCCCGCT
TATATTTGTATCCACACTTATCACTCACCTGTTCGGTGGCTCTGCCGGCCGTGAGGGTGCTGCACTGCAGATGGGAGGCA
GCATCGGAAGCTCTATAGGCAGGGTATTCAGATTTGATGAAAAGGACAAGCATGTCATGATTATGTGTGGCATGAGCGCT
GCATTCAGTGCACTGTTTGGCACTCCGATGGCAGCCGCTATTTTCTCCATGGAGATGATAAGCGTCGGTGTCATGTATTA
TATAGCACTCGTTCCATGTGTGATAAGCTCCCTCATCGCTCACGGTATCGCATCATACTTCAATGTTACAAATGAATTTT
TTGCTATTGAAAACATACCGGACTTTACTATTTTAAACTCAGTAAAAATCTCTGTGCTTGCAATACTGTGCGCACTCGTA
AGCATACTCTTTTGTGTGGCCCTTCACTCAGGTGAGGCGCTGTACAAAAAATATCTGCCAAACAAATATACAAGAGTATT
CATTGGTGGCTGCTTTATCATCATAGCAACTATGCTTGTAGGAAACCAGACATACAACGGCACCGGAATGAGTGTCATCC
AAAGCAGTATAGACGGCTCTGTCAGACCTGAAGCATTTCTGCTAAAAATCATCTTCACCGCACTGACTCTTGGCGCAGGC
TTTAAGGGCGGCGAGATTGTACCATCCTTTTTCATAGGCGCAACATTTGGATGCCTGTTCGGCAATCTGACAGGCTTTGA
GCCATCGCTGTGTACAGCTGTCGGCATGATTTCACTGTTCTGTGGTGTCACCAACTGTCCGATCACATCGCTGCTCATCA
GCTTTGAGCTGTTTGGCTACGACGGCATGCCATACTTTCTTTTGGCAATTCCATTCAGCTATATGCTGTCAGGATACTTT
GGCCTGTATCGCAGCCAGAAAATCGTATATTCAAAATACAAGACAAGCTACATAAATAAATCAACTCACTAA

Upstream 100 bases:

>100_bases
GTTTTATTTAGTTATTATAACATCATAAAGTGCAACTTGTAAATTAAATTAGTTAATGTTAATATCAAATTAAGAAAAAG
TTTAAAAGAGGTGTAACAAA

Downstream 100 bases:

>100_bases
CATTTGCAAACTGCAACCAGGCATGATACCCCAGGTATTATTGCCTGGTCTTTTATTGTGTAAAGAGCTTTATCTCCCGC
AGAAGATTCATCTGCAAGAA

Product: chloride channel protein EriC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MNETTRQLIVHKVKHNTKRLITSIKWVIFSIVVGIVAGSCGTAFYFALSVVTDFRMKYPWLIYFLPIGGLAIVGLYHLCK
DDNDTGTNLVISAIHSGDKVPFIMAPLIFVSTLITHLFGGSAGREGAALQMGGSIGSSIGRVFRFDEKDKHVMIMCGMSA
AFSALFGTPMAAAIFSMEMISVGVMYYIALVPCVISSLIAHGIASYFNVTNEFFAIENIPDFTILNSVKISVLAILCALV
SILFCVALHSGEALYKKYLPNKYTRVFIGGCFIIIATMLVGNQTYNGTGMSVIQSSIDGSVRPEAFLLKIIFTALTLGAG
FKGGEIVPSFFIGATFGCLFGNLTGFEPSLCTAVGMISLFCGVTNCPITSLLISFELFGYDGMPYFLLAIPFSYMLSGYF
GLYRSQKIVYSKYKTSYINKSTH

Sequences:

>Translated_423_residues
MNETTRQLIVHKVKHNTKRLITSIKWVIFSIVVGIVAGSCGTAFYFALSVVTDFRMKYPWLIYFLPIGGLAIVGLYHLCK
DDNDTGTNLVISAIHSGDKVPFIMAPLIFVSTLITHLFGGSAGREGAALQMGGSIGSSIGRVFRFDEKDKHVMIMCGMSA
AFSALFGTPMAAAIFSMEMISVGVMYYIALVPCVISSLIAHGIASYFNVTNEFFAIENIPDFTILNSVKISVLAILCALV
SILFCVALHSGEALYKKYLPNKYTRVFIGGCFIIIATMLVGNQTYNGTGMSVIQSSIDGSVRPEAFLLKIIFTALTLGAG
FKGGEIVPSFFIGATFGCLFGNLTGFEPSLCTAVGMISLFCGVTNCPITSLLISFELFGYDGMPYFLLAIPFSYMLSGYF
GLYRSQKIVYSKYKTSYINKSTH
>Mature_423_residues
MNETTRQLIVHKVKHNTKRLITSIKWVIFSIVVGIVAGSCGTAFYFALSVVTDFRMKYPWLIYFLPIGGLAIVGLYHLCK
DDNDTGTNLVISAIHSGDKVPFIMAPLIFVSTLITHLFGGSAGREGAALQMGGSIGSSIGRVFRFDEKDKHVMIMCGMSA
AFSALFGTPMAAAIFSMEMISVGVMYYIALVPCVISSLIAHGIASYFNVTNEFFAIENIPDFTILNSVKISVLAILCALV
SILFCVALHSGEALYKKYLPNKYTRVFIGGCFIIIATMLVGNQTYNGTGMSVIQSSIDGSVRPEAFLLKIIFTALTLGAG
FKGGEIVPSFFIGATFGCLFGNLTGFEPSLCTAVGMISLFCGVTNCPITSLLISFELFGYDGMPYFLLAIPFSYMLSGYF
GLYRSQKIVYSKYKTSYINKSTH

Specific function: Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 45987; Mature: 45987

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETTRQLIVHKVKHNTKRLITSIKWVIFSIVVGIVAGSCGTAFYFALSVVTDFRMKYPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCE
LIYFLPIGGLAIVGLYHLCKDDNDTGTNLVISAIHSGDKVPFIMAPLIFVSTLITHLFGG
EEEEECHHHHHHHHHHHHHCCCCCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
SAGREGAALQMGGSIGSSIGRVFRFDEKDKHVMIMCGMSAAFSALFGTPMAAAIFSMEMI
CCCCCCCEEEECCHHHHHHHHHEECCCCCCEEEEEECHHHHHHHHHCCHHHHHHHHHHHH
SVGVMYYIALVPCVISSLIAHGIASYFNVTNEFFAIENIPDFTILNSVKISVLAILCALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
SILFCVALHSGEALYKKYLPNKYTRVFIGGCFIIIATMLVGNQTYNGTGMSVIQSSIDGS
HHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
VRPEAFLLKIIFTALTLGAGFKGGEIVPSFFIGATFGCLFGNLTGFEPSLCTAVGMISLF
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
CGVTNCPITSLLISFELFGYDGMPYFLLAIPFSYMLSGYFGLYRSQKIVYSKYKTSYINK
HCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
STH
CCC
>Mature Secondary Structure
MNETTRQLIVHKVKHNTKRLITSIKWVIFSIVVGIVAGSCGTAFYFALSVVTDFRMKYPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCE
LIYFLPIGGLAIVGLYHLCKDDNDTGTNLVISAIHSGDKVPFIMAPLIFVSTLITHLFGG
EEEEECHHHHHHHHHHHHHCCCCCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
SAGREGAALQMGGSIGSSIGRVFRFDEKDKHVMIMCGMSAAFSALFGTPMAAAIFSMEMI
CCCCCCCEEEECCHHHHHHHHHEECCCCCCEEEEEECHHHHHHHHHCCHHHHHHHHHHHH
SVGVMYYIALVPCVISSLIAHGIASYFNVTNEFFAIENIPDFTILNSVKISVLAILCALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
SILFCVALHSGEALYKKYLPNKYTRVFIGGCFIIIATMLVGNQTYNGTGMSVIQSSIDGS
HHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
VRPEAFLLKIIFTALTLGAGFKGGEIVPSFFIGATFGCLFGNLTGFEPSLCTAVGMISLF
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
CGVTNCPITSLLISFELFGYDGMPYFLLAIPFSYMLSGYFGLYRSQKIVYSKYKTSYINK
HCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
STH
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA