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The map label for this gene is mcp4 [H]

Identifier: 238924074

GI number: 238924074

Start: 1589021

End: 1590748

Strand: Direct

Name: mcp4 [H]

Synonym: EUBREC_1712

Alternate gene names: 238924074

Gene position: 1589021-1590748 (Clockwise)

Preceding gene: 238924072

Following gene: 238924075

Centisome position: 46.06

GC content: 48.78

Gene sequence:

>1728_bases
ATGAACAAAGGCAAAATTCGTACAAGGAGACTCACAATCCGCGCGAAGATCCTGATTCCGTCAATCATAATCGTTGTACT
CGTCTGTGGTTTGATGGGATACAATTCCTACACGCGTTTTGAGAAAAGCATGGTGAGGATGGGCGTTGAGGAAGCAGACA
TGGCGGCAACGATCGTTGCGGATTCGCTGGATGCCAAGCTGGTATACAAAGTGACGGTAGGATCGGAAGGTACGCAGGTC
TATCAGAATCTGCAAGGAGATCTCAGAAAAAAGCAAAAAGCATGCGGAATTGCTTTTTTATACACATTGTATACGGACGG
AAAGAAAGTGTATTATGGTGTGGATTCGGACGAGGATGCGGCAAAAGTCGGTGATGAATTTGCGGATTCATACGCGGAAC
TGGAGCCGGTGTTCGGTGGAAAGGAATACATTCAGGATTACATCGACCATACAGAAGACGGAGATCTGATTACGGTATAC
AAGCCTATTGAGGACAATGCAGGCAAGGTTGTTGCAATACTTGGATGCGATTATGATGCGTCATCGATTACAGCAGAATT
ACAGAAGGCAGTTGTCCAGACGTTACAGATCGGAGGCATCTGTCTGATTCTGGCAATCCTGATTCTGACGATTATCGTTA
GCAGGATTACAAAGGGACTGATGCAGGTAAATGCGAAGATTTATGATCTGGTACATAATGAGGGTGACCTGACACAGAAA
CTGGATGTCAGAAGCGGGGATGAGCTGGAACTGATTGCGGGCAATGTGAATGAGTTGTTAGCGTATATCCGCAAGATTAT
GATCGGAATTTCGTCCGGATCCATGCGGCTTATGTCTTCTTCCCGCAAAATGGTGGATCATCTGAGCTCTGCGGATGAAA
GCATTACCGATGTGTCGGCAACGATGCAGGAGATGAGTGCGGCGATGGAGGAAACGACTTCTTCACTCAATCAGATCACG
GAGGCAATTGACGAAATCTATTCATCGGTAGAGCGTATTGCAGGCAATGCGGATGCCGGAAAAGTCTCTTCTCAGGAGAT
GGAGAGCCGTGCTTCCGGGGCGAATGATGCAGCAGAGGAGGGGCAGAAGAAAGCAAACATTGAGACCGAGAAGATGGCGG
CTTCTTTAAATGAGAAGATTGCAAAGTCCAAATCGGTGGAACAGATCGAGATTCTTACTTCCAACATTATCGAGATTACA
GAACAGACCAATCTTCTTGCGCTGAATGCAAGTATTGAAGCGGCACGCGCAGGGGAAGCAGGACGCGGCTTTGCGGTGGT
TGCGGATGAGATTGGAAAGCTGGCAGGTAACTCTGCGGATGCCGCAGCAAAAATCCGCCAGGTGAGTGCAGAGGTCATTC
AGGCAGTGGATGAACTGGCAGAGGGATCGCAGCAGATGATCGAATTTGTCCGCAATTCCACAGAGGAAGGCTTCGGAGGT
CTTGTTGCAACGAGTGAAAATTATGCGACCGATGCGAATGCAATGCGTGCAATGATGGAGCAGTTCGCGCAGACTGCGGA
AGAACTTCGCAGCACGATGGATGGCATCCGTGAATCCATCTCTGCAGTCAACATTGCCGTGGAAGAGAGTGCCAAGGGCA
TTGCGGGAGTTTCCGAGTCTTCCGTACAGCTTACCGGTAACGTCAATGATATCCAAAGCGAGGCTTCCGACAACAATGGC
ATCGCAGAGGATCTGGCAACGGAAGTCGGCAAATTCAAGCTTGAGTAG

Upstream 100 bases:

>100_bases
ATTCCTATTCGATAATAATTGACGAACATGCCCGTTGCCCATCGTTCGATAATGTGTTATACTTGTGCCATACAATGTAG
ACATAAGGAGAAGCGTTGAA

Downstream 100 bases:

>100_bases
AGCTTATATAAAGATGGGGAACTAAACCAATTCCCGAATAGAAAAATCGCTTAGACCGTGAGTTTGAGCGATTTTTTGTT
TAAGGATTATAGATGTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MNKGKIRTRRLTIRAKILIPSIIIVVLVCGLMGYNSYTRFEKSMVRMGVEEADMAATIVADSLDAKLVYKVTVGSEGTQV
YQNLQGDLRKKQKACGIAFLYTLYTDGKKVYYGVDSDEDAAKVGDEFADSYAELEPVFGGKEYIQDYIDHTEDGDLITVY
KPIEDNAGKVVAILGCDYDASSITAELQKAVVQTLQIGGICLILAILILTIIVSRITKGLMQVNAKIYDLVHNEGDLTQK
LDVRSGDELELIAGNVNELLAYIRKIMIGISSGSMRLMSSSRKMVDHLSSADESITDVSATMQEMSAAMEETTSSLNQIT
EAIDEIYSSVERIAGNADAGKVSSQEMESRASGANDAAEEGQKKANIETEKMAASLNEKIAKSKSVEQIEILTSNIIEIT
EQTNLLALNASIEAARAGEAGRGFAVVADEIGKLAGNSADAAAKIRQVSAEVIQAVDELAEGSQQMIEFVRNSTEEGFGG
LVATSENYATDANAMRAMMEQFAQTAEELRSTMDGIRESISAVNIAVEESAKGIAGVSESSVQLTGNVNDIQSEASDNNG
IAEDLATEVGKFKLE

Sequences:

>Translated_575_residues
MNKGKIRTRRLTIRAKILIPSIIIVVLVCGLMGYNSYTRFEKSMVRMGVEEADMAATIVADSLDAKLVYKVTVGSEGTQV
YQNLQGDLRKKQKACGIAFLYTLYTDGKKVYYGVDSDEDAAKVGDEFADSYAELEPVFGGKEYIQDYIDHTEDGDLITVY
KPIEDNAGKVVAILGCDYDASSITAELQKAVVQTLQIGGICLILAILILTIIVSRITKGLMQVNAKIYDLVHNEGDLTQK
LDVRSGDELELIAGNVNELLAYIRKIMIGISSGSMRLMSSSRKMVDHLSSADESITDVSATMQEMSAAMEETTSSLNQIT
EAIDEIYSSVERIAGNADAGKVSSQEMESRASGANDAAEEGQKKANIETEKMAASLNEKIAKSKSVEQIEILTSNIIEIT
EQTNLLALNASIEAARAGEAGRGFAVVADEIGKLAGNSADAAAKIRQVSAEVIQAVDELAEGSQQMIEFVRNSTEEGFGG
LVATSENYATDANAMRAMMEQFAQTAEELRSTMDGIRESISAVNIAVEESAKGIAGVSESSVQLTGNVNDIQSEASDNNG
IAEDLATEVGKFKLE
>Mature_575_residues
MNKGKIRTRRLTIRAKILIPSIIIVVLVCGLMGYNSYTRFEKSMVRMGVEEADMAATIVADSLDAKLVYKVTVGSEGTQV
YQNLQGDLRKKQKACGIAFLYTLYTDGKKVYYGVDSDEDAAKVGDEFADSYAELEPVFGGKEYIQDYIDHTEDGDLITVY
KPIEDNAGKVVAILGCDYDASSITAELQKAVVQTLQIGGICLILAILILTIIVSRITKGLMQVNAKIYDLVHNEGDLTQK
LDVRSGDELELIAGNVNELLAYIRKIMIGISSGSMRLMSSSRKMVDHLSSADESITDVSATMQEMSAAMEETTSSLNQIT
EAIDEIYSSVERIAGNADAGKVSSQEMESRASGANDAAEEGQKKANIETEKMAASLNEKIAKSKSVEQIEILTSNIIEIT
EQTNLLALNASIEAARAGEAGRGFAVVADEIGKLAGNSADAAAKIRQVSAEVIQAVDELAEGSQQMIEFVRNSTEEGFGG
LVATSENYATDANAMRAMMEQFAQTAEELRSTMDGIRESISAVNIAVEESAKGIAGVSESSVQLTGNVNDIQSEASDNNG
IAEDLATEVGKFKLE

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=265, Percent_Identity=29.0566037735849, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788195, Length=164, Percent_Identity=38.4146341463415, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789453, Length=198, Percent_Identity=32.8282828282828, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367378, Length=229, Percent_Identity=31.0043668122271, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788194, Length=463, Percent_Identity=24.1900647948164, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 61841; Mature: 61841

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKGKIRTRRLTIRAKILIPSIIIVVLVCGLMGYNSYTRFEKSMVRMGVEEADMAATIVA
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHH
DSLDAKLVYKVTVGSEGTQVYQNLQGDLRKKQKACGIAFLYTLYTDGKKVYYGVDSDEDA
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHEEEEEEECCCEEEECCCCCCHH
AKVGDEFADSYAELEPVFGGKEYIQDYIDHTEDGDLITVYKPIEDNAGKVVAILGCDYDA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCH
SSITAELQKAVVQTLQIGGICLILAILILTIIVSRITKGLMQVNAKIYDLVHNEGDLTQK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHE
LDVRSGDELELIAGNVNELLAYIRKIMIGISSGSMRLMSSSRKMVDHLSSADESITDVSA
ECCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
TMQEMSAAMEETTSSLNQITEAIDEIYSSVERIAGNADAGKVSSQEMESRASGANDAAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHH
GQKKANIETEKMAASLNEKIAKSKSVEQIEILTSNIIEITEQTNLLALNASIEAARAGEA
CHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCC
GRGFAVVADEIGKLAGNSADAAAKIRQVSAEVIQAVDELAEGSQQMIEFVRNSTEEGFGG
CCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
LVATSENYATDANAMRAMMEQFAQTAEELRSTMDGIRESISAVNIAVEESAKGIAGVSES
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCC
SVQLTGNVNDIQSEASDNNGIAEDLATEVGKFKLE
CEEEECCHHHHHHHCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNKGKIRTRRLTIRAKILIPSIIIVVLVCGLMGYNSYTRFEKSMVRMGVEEADMAATIVA
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHH
DSLDAKLVYKVTVGSEGTQVYQNLQGDLRKKQKACGIAFLYTLYTDGKKVYYGVDSDEDA
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHEEEEEEECCCEEEECCCCCCHH
AKVGDEFADSYAELEPVFGGKEYIQDYIDHTEDGDLITVYKPIEDNAGKVVAILGCDYDA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCH
SSITAELQKAVVQTLQIGGICLILAILILTIIVSRITKGLMQVNAKIYDLVHNEGDLTQK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHE
LDVRSGDELELIAGNVNELLAYIRKIMIGISSGSMRLMSSSRKMVDHLSSADESITDVSA
ECCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
TMQEMSAAMEETTSSLNQITEAIDEIYSSVERIAGNADAGKVSSQEMESRASGANDAAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHH
GQKKANIETEKMAASLNEKIAKSKSVEQIEILTSNIIEITEQTNLLALNASIEAARAGEA
CHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCC
GRGFAVVADEIGKLAGNSADAAAKIRQVSAEVIQAVDELAEGSQQMIEFVRNSTEEGFGG
CCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
LVATSENYATDANAMRAMMEQFAQTAEELRSTMDGIRESISAVNIAVEESAKGIAGVSES
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCC
SVQLTGNVNDIQSEASDNNGIAEDLATEVGKFKLE
CEEEECCHHHHHHHCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]