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The map label for this gene is coaD

Identifier: 238924040

GI number: 238924040

Start: 1561454

End: 1561939

Strand: Direct

Name: coaD

Synonym: EUBREC_1678

Alternate gene names: 238924040

Gene position: 1561454-1561939 (Clockwise)

Preceding gene: 238924039

Following gene: 238924041

Centisome position: 45.26

GC content: 38.07

Gene sequence:

>486_bases
ATGAAGGTAGGAATTTATCCGGGAAGCTTTGATCCGGTGACATTTGGACACCTGGATATAATAGAGCGTTCAGCAAAAAT
AGTTGACGAGCTGGTTGTCGGAGTACTCAATAATAGTGCAAAAAACTCGTTGTTTTCTTTGGAAGAACGTGTTAGTATGA
TAAAGGAAATGACAGCACATATACCAAACGTTAGGGTAGGGTGCTTCGAAGGACTTTTAGTTGATTATATGAAGAAAATC
AATGCAACAATCATAATAAGAGGATTGCGTGCAGTGACAGATTTTGAGTATGAGCTGCAGATTGCACAGGCTAACGGAGT
GCAGAATCCGGAAATAGAGACGGTTTTTCTCACTTCTAGCCTCAATTATTCATATTTAAGCTCTACAATTGTCAAGGAAT
TTGCATCATACGGAGGAGATATATCAAAGTTCGTACCTGAACAGTTCATTGATAGAATTTATGCCAAATACAATATTACC
AGGTAA

Upstream 100 bases:

>100_bases
GATTTTGATTATCTCACAGAGCTTGGCTATGAGATAGTCAAAGAAAAAATTTATAAGACAAACAAGCATGTTTTCATAAA
GCGTGCATAGGAGATACAAT

Downstream 100 bases:

>100_bases
GGAGACAGTATTTATGAGCAGTAAAATGGAACAGATTATTGAAGAAATCGAAGATTATATTGATGGCTGCAAGCCGTCAC
CTATTTCAAGAAACAAGATT

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKVGIYPGSFDPVTFGHLDIIERSAKIVDELVVGVLNNSAKNSLFSLEERVSMIKEMTAHIPNVRVGCFEGLLVDYMKKI
NATIIIRGLRAVTDFEYELQIAQANGVQNPEIETVFLTSSLNYSYLSSTIVKEFASYGGDISKFVPEQFIDRIYAKYNIT
R

Sequences:

>Translated_161_residues
MKVGIYPGSFDPVTFGHLDIIERSAKIVDELVVGVLNNSAKNSLFSLEERVSMIKEMTAHIPNVRVGCFEGLLVDYMKKI
NATIIIRGLRAVTDFEYELQIAQANGVQNPEIETVFLTSSLNYSYLSSTIVKEFASYGGDISKFVPEQFIDRIYAKYNIT
R
>Mature_161_residues
MKVGIYPGSFDPVTFGHLDIIERSAKIVDELVVGVLNNSAKNSLFSLEERVSMIKEMTAHIPNVRVGCFEGLLVDYMKKI
NATIIIRGLRAVTDFEYELQIAQANGVQNPEIETVFLTSSLNYSYLSSTIVKEFASYGGDISKFVPEQFIDRIYAKYNIT
R

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=43.8709677419355, Blast_Score=158, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_EUBR3 (C4Z9Y1)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002937556.1
- ProteinModelPortal:   C4Z9Y1
- GeneID:   7963633
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_1678
- ProtClustDB:   CLSK2506132
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18097; Mature: 18097

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGIYPGSFDPVTFGHLDIIERSAKIVDELVVGVLNNSAKNSLFSLEERVSMIKEMTAH
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IPNVRVGCFEGLLVDYMKKINATIIIRGLRAVTDFEYELQIAQANGVQNPEIETVFLTSS
CCCCCHHHHHHHHHHHHHHCCHHEEEEHHHHHHCCCEEEEEECCCCCCCCCEEEEEEECC
LNYSYLSSTIVKEFASYGGDISKFVPEQFIDRIYAKYNITR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVGIYPGSFDPVTFGHLDIIERSAKIVDELVVGVLNNSAKNSLFSLEERVSMIKEMTAH
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IPNVRVGCFEGLLVDYMKKINATIIIRGLRAVTDFEYELQIAQANGVQNPEIETVFLTSS
CCCCCHHHHHHHHHHHHHHCCHHEEEEHHHHHHCCCEEEEEECCCCCCCCCEEEEEEECC
LNYSYLSSTIVKEFASYGGDISKFVPEQFIDRIYAKYNITR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA