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The map label for this gene is pgsA [H]

Identifier: 238924038

GI number: 238924038

Start: 1560323

End: 1560871

Strand: Direct

Name: pgsA [H]

Synonym: EUBREC_1676

Alternate gene names: 238924038

Gene position: 1560323-1560871 (Clockwise)

Preceding gene: 238924037

Following gene: 238924039

Centisome position: 45.23

GC content: 36.43

Gene sequence:

>549_bases
ATGAATTTACCAAACAAACTTACAATCTTAAGAGTGATACTTATTCCGTTTTTTGTATTTTTCCTTATTTCACCGTTTTT
TGACGGATACGGAAATTATATAGCGCTTGCGATATTTATCATTGCAAGTCTGACCGATATGGCTGACGGAAAAATTGCAA
GAAAATACAATCTTGTTACAAATTTCGGCAAGTTTATGGATCCGCTTGCAGACAAGCTGCTTGTATGCTCTGCAATGATA
TGCCTTGTTGATTTAAAGCTCATCCCTGTATGGGTTGTGCTTATTATCATTGCAAGAGAGTTTATCATAAGCGGCTTCAG
ACTCGTTGCATCAGACAATGGAATTGTCATTGCAGCAAGCTACTGGGGAAAATTTAAGACAACCTTCCAGATGCTTATGG
TTATTGTTATTATTTTTAATATCAATCTGCAGCTTGGCTGGTTAAATATCCTTGGAACAATCCTCATTTATGTGGCACTT
GTGCTCACAGTTGTTTCACTTATTGACTATATTGCAAAGAATAAGGACGTCTTAAAGGACCAGAAATAG

Upstream 100 bases:

>100_bases
ATATATTCATCAACACTGATGAGACACTTATGACCGGTGATATATGCAAGGTTATGGTGACGGGTGCGTATGAATATGAT
TTGATAGGAGAACTTGTAAA

Downstream 100 bases:

>100_bases
ACTATAACAGGGAGAAAAGTATGAGAATAATAGCAGGAACGGCGAGAAGCCTCCCTCTAAAGACTATCGAGGGAAAAGAT
ACAAGACCGACTACTGACAA

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MNLPNKLTILRVILIPFFVFFLISPFFDGYGNYIALAIFIIASLTDMADGKIARKYNLVTNFGKFMDPLADKLLVCSAMI
CLVDLKLIPVWVVLIIIAREFIISGFRLVASDNGIVIAASYWGKFKTTFQMLMVIVIIFNINLQLGWLNILGTILIYVAL
VLTVVSLIDYIAKNKDVLKDQK

Sequences:

>Translated_182_residues
MNLPNKLTILRVILIPFFVFFLISPFFDGYGNYIALAIFIIASLTDMADGKIARKYNLVTNFGKFMDPLADKLLVCSAMI
CLVDLKLIPVWVVLIIIAREFIISGFRLVASDNGIVIAASYWGKFKTTFQMLMVIVIIFNINLQLGWLNILGTILIYVAL
VLTVVSLIDYIAKNKDVLKDQK
>Mature_182_residues
MNLPNKLTILRVILIPFFVFFLISPFFDGYGNYIALAIFIIASLTDMADGKIARKYNLVTNFGKFMDPLADKLLVCSAMI
CLVDLKLIPVWVVLIIIAREFIISGFRLVASDNGIVIAASYWGKFKTTFQMLMVIVIIFNINLQLGWLNILGTILIYVAL
VLTVVSLIDYIAKNKDVLKDQK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=185, Percent_Identity=40.5405405405405, Blast_Score=116, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320059, Length=107, Percent_Identity=38.3177570093458, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650130, Length=106, Percent_Identity=34.9056603773585, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650126, Length=106, Percent_Identity=34.9056603773585, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650128, Length=106, Percent_Identity=34.9056603773585, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20501; Mature: 20501

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKLTILRVILIPFFVFFLISPFFDGYGNYIALAIFIIASLTDMADGKIARKYNLVT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NFGKFMDPLADKLLVCSAMICLVDLKLIPVWVVLIIIAREFIISGFRLVASDNGIVIAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEC
YWGKFKTTFQMLMVIVIIFNINLQLGWLNILGTILIYVALVLTVVSLIDYIAKNKDVLKD
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
QK
CC
>Mature Secondary Structure
MNLPNKLTILRVILIPFFVFFLISPFFDGYGNYIALAIFIIASLTDMADGKIARKYNLVT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NFGKFMDPLADKLLVCSAMICLVDLKLIPVWVVLIIIAREFIISGFRLVASDNGIVIAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEC
YWGKFKTTFQMLMVIVIIFNINLQLGWLNILGTILIYVALVLTVVSLIDYIAKNKDVLKD
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
QK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA