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The map label for this gene is ruvA [H]

Identifier: 238924017

GI number: 238924017

Start: 1540937

End: 1541554

Strand: Direct

Name: ruvA [H]

Synonym: EUBREC_1655

Alternate gene names: 238924017

Gene position: 1540937-1541554 (Clockwise)

Preceding gene: 238924016

Following gene: 238924018

Centisome position: 44.67

GC content: 44.01

Gene sequence:

>618_bases
ATGGATTCAATGTATGCATATATAAAAGGAGAGCTTGCAGAAAAAAATATAGACAGCATTGTAGTGGAGGCTGCAGGTGT
AGGCTATCTCATTTACATACCGACGCAGTATTTTGATATGCTGCCTGACGAGGGAGAGGATGTAAAAATTTACACCTACC
TATGTGTCAGGGAGGATGCCATGATACTTTATGGCTTTTTGAGCAAGGATGATCTTGAAATCTTTAAGCTGCTGATTACA
GTCAGCGGAATCGGACCAAAGGGAGGTCTTGCCATTTTGTCAACTCTGCCTGCCGATGATTTGCGTTTTGCGATTCTATC
GGGGGATTCAAAGGCTATATCAAAGGCACCGGGAATAGGTGCAAAGACGGCTCAGAGAGTGATACTTGATTTAAAGGACA
AGCTGTCGCTTGAGGATGCATTTGAAAAGAAGCTTGAGAATCAGGCATCCGGTGCTGCTGTATCCATGAACAGCACTGTG
AAAAATGATGCTGTCATGGCGCTCAATGCGCTTGGATACTCATCTACTGAGAGTCTTAAGGCAGTGTCCAAGGTTGATAT
CACAGAGGATATGGATGTAGAGGATGTGCTGAAGCTTGCACTCAAAAATATGGGCTGA

Upstream 100 bases:

>100_bases
TGTATAGTTTTAATGGGCTGTAATCTACGTATATTTAATAATAAAAGGAGATGCTGCTGTTTTATGCCTGTGTGTCAGGC
TACAGTCGAAACAGTAACAA

Downstream 100 bases:

>100_bases
TTGGACAAGCTGTAAGCTTAAAACAGAAACGGGGAACAAAACGTGAAAAGAGTAATTTCCACACAATTGCAGGAAGAGGA
CATAAAGATAGAGAAATCCC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MDSMYAYIKGELAEKNIDSIVVEAAGVGYLIYIPTQYFDMLPDEGEDVKIYTYLCVREDAMILYGFLSKDDLEIFKLLIT
VSGIGPKGGLAILSTLPADDLRFAILSGDSKAISKAPGIGAKTAQRVILDLKDKLSLEDAFEKKLENQASGAAVSMNSTV
KNDAVMALNALGYSSTESLKAVSKVDITEDMDVEDVLKLALKNMG

Sequences:

>Translated_205_residues
MDSMYAYIKGELAEKNIDSIVVEAAGVGYLIYIPTQYFDMLPDEGEDVKIYTYLCVREDAMILYGFLSKDDLEIFKLLIT
VSGIGPKGGLAILSTLPADDLRFAILSGDSKAISKAPGIGAKTAQRVILDLKDKLSLEDAFEKKLENQASGAAVSMNSTV
KNDAVMALNALGYSSTESLKAVSKVDITEDMDVEDVLKLALKNMG
>Mature_205_residues
MDSMYAYIKGELAEKNIDSIVVEAAGVGYLIYIPTQYFDMLPDEGEDVKIYTYLCVREDAMILYGFLSKDDLEIFKLLIT
VSGIGPKGGLAILSTLPADDLRFAILSGDSKAISKAPGIGAKTAQRVILDLKDKLSLEDAFEKKLENQASGAAVSMNSTV
KNDAVMALNALGYSSTESLKAVSKVDITEDMDVEDVLKLALKNMG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=35.4679802955665, Blast_Score=127, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22149; Mature: 22149

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSMYAYIKGELAEKNIDSIVVEAAGVGYLIYIPTQYFDMLPDEGEDVKIYTYLCVREDA
CCCEEEEEECHHHHCCHHHEEEEECCCEEEEEECCHHHHCCCCCCCCEEEEEEEEEECCC
MILYGFLSKDDLEIFKLLITVSGIGPKGGLAILSTLPADDLRFAILSGDSKAISKAPGIG
EEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHCCCCCC
AKTAQRVILDLKDKLSLEDAFEKKLENQASGAAVSMNSTVKNDAVMALNALGYSSTESLK
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCHHHHH
AVSKVDITEDMDVEDVLKLALKNMG
HHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDSMYAYIKGELAEKNIDSIVVEAAGVGYLIYIPTQYFDMLPDEGEDVKIYTYLCVREDA
CCCEEEEEECHHHHCCHHHEEEEECCCEEEEEECCHHHHCCCCCCCCEEEEEEEEEECCC
MILYGFLSKDDLEIFKLLITVSGIGPKGGLAILSTLPADDLRFAILSGDSKAISKAPGIG
EEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHCCCCCC
AKTAQRVILDLKDKLSLEDAFEKKLENQASGAAVSMNSTVKNDAVMALNALGYSSTESLK
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCHHHHH
AVSKVDITEDMDVEDVLKLALKNMG
HHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA