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The map label for this gene is hexR [C]

Identifier: 238923996

GI number: 238923996

Start: 1522040

End: 1522972

Strand: Direct

Name: hexR [C]

Synonym: EUBREC_1634

Alternate gene names: 238923996

Gene position: 1522040-1522972 (Clockwise)

Preceding gene: 238923993

Following gene: 238923997

Centisome position: 44.12

GC content: 42.34

Gene sequence:

>933_bases
ATGATGTCAAATACTAACGACTTACTTAACAGGATAAATGCTAAATACAGTACGATGAGCAAGGGGCACAAGCTGCTTGC
TACATACATAACTGATAATTATGATAAGGCTGTCTTTCTGACAGCGGCTAAGATGGGCGAGACGGTAGGAATTTCTGAGT
CTACGGTTGTCAGGTTCGCTACATCGCTCGGATATAAGGGATATCCCGATTTTCAGAAGGCACTTGAGGAGCTTGTAAGG
AACAAGCTCAATTCGGTTCAGCGAATGGAGGTCACATATGGGCGTATCAGCCAGTCACAGATTCTTGAGACTGTACTGCA
GTCTGATCGTGACAAGATTAAGACCACTCTGGAAAAAATTGATGCGGATGCATTTGACTTGGCGGTAGATACTATTTTAC
AGTCAAGGAAAATTTATATTGTCGGAATCAGAAGCTGTGCACCTCTTGCGAGCTTTCTTGCATTTTATATGAATCTGATG
TTTGAGGATGTGTGTCTGCTTACGACAAACAGCTCGAGCGAGCTTTTTGAGCAGATGGTGCGCATTGGCAAGGATGATGT
GATTATCGGTATCAGCTTTCCTCGTTACTCTATGCGTACTCTTAAGGCGTTAGAATTTGCCAACAACAGGAGTGCAAAGG
TTATAACTATCACAGACAGCATTCATTCACCGATGAATCTGTATTCTTCATGTAATCTGATTGCCGACAGTGATATGGCC
TCTATAGTTGATTCACTTGTTGCTCCGCTTTCTGTCATTAATGCCCTGATTGTGGCTCTTTGCATGAAAAAGCAGAATAT
TGTCGCAAAGACACTGACAGAGCTTGAGGATATATGGAATGAGTATCAGGTGTACGAGAATGATGAGATTGATTACATTG
ATGACTCTATAAAGGTACATTACGCTAAGCTGGGGGATTCGCAGGATGAGTAA

Upstream 100 bases:

>100_bases
TATAGAGGAAAAAAGTGATAATATTTTAAGGTATGAAAAAATCGCTGCAGGTCACACAAATATGTGAAGCACAGCCATAA
ACGGGAAAGCTCAGGAGTAT

Downstream 100 bases:

>100_bases
GAAAATTATTGTGGTAGGTGGCGGAGCCGCCGGAATGCTTGCGGCGTATTTTGCTGCAGAAGCAGGGAATAAGATTACGC
TTCTTGAAAAAAATGAAAAA

Product: N-acetylmannosamine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MMSNTNDLLNRINAKYSTMSKGHKLLATYITDNYDKAVFLTAAKMGETVGISESTVVRFATSLGYKGYPDFQKALEELVR
NKLNSVQRMEVTYGRISQSQILETVLQSDRDKIKTTLEKIDADAFDLAVDTILQSRKIYIVGIRSCAPLASFLAFYMNLM
FEDVCLLTTNSSSELFEQMVRIGKDDVIIGISFPRYSMRTLKALEFANNRSAKVITITDSIHSPMNLYSSCNLIADSDMA
SIVDSLVAPLSVINALIVALCMKKQNIVAKTLTELEDIWNEYQVYENDEIDYIDDSIKVHYAKLGDSQDE

Sequences:

>Translated_310_residues
MMSNTNDLLNRINAKYSTMSKGHKLLATYITDNYDKAVFLTAAKMGETVGISESTVVRFATSLGYKGYPDFQKALEELVR
NKLNSVQRMEVTYGRISQSQILETVLQSDRDKIKTTLEKIDADAFDLAVDTILQSRKIYIVGIRSCAPLASFLAFYMNLM
FEDVCLLTTNSSSELFEQMVRIGKDDVIIGISFPRYSMRTLKALEFANNRSAKVITITDSIHSPMNLYSSCNLIADSDMA
SIVDSLVAPLSVINALIVALCMKKQNIVAKTLTELEDIWNEYQVYENDEIDYIDDSIKVHYAKLGDSQDE
>Mature_310_residues
MMSNTNDLLNRINAKYSTMSKGHKLLATYITDNYDKAVFLTAAKMGETVGISESTVVRFATSLGYKGYPDFQKALEELVR
NKLNSVQRMEVTYGRISQSQILETVLQSDRDKIKTTLEKIDADAFDLAVDTILQSRKIYIVGIRSCAPLASFLAFYMNLM
FEDVCLLTTNSSSELFEQMVRIGKDDVIIGISFPRYSMRTLKALEFANNRSAKVITITDSIHSPMNLYSSCNLIADSDMA
SIVDSLVAPLSVINALIVALCMKKQNIVAKTLTELEDIWNEYQVYENDEIDYIDDSIKVHYAKLGDSQDE

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=274, Percent_Identity=24.8175182481752, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 34858; Mature: 34858

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSNTNDLLNRINAKYSTMSKGHKLLATYITDNYDKAVFLTAAKMGETVGISESTVVRFA
CCCCHHHHHHHHCCHHHHHHCCHHEEEHHHCCCCCCEEEEEHHHCCCCCCCCHHHHHHHH
TSLGYKGYPDFQKALEELVRNKLNSVQRMEVTYGRISQSQILETVLQSDRDKIKTTLEKI
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHH
DADAFDLAVDTILQSRKIYIVGIRSCAPLASFLAFYMNLMFEDVCLLTTNSSSELFEQMV
CCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHH
RIGKDDVIIGISFPRYSMRTLKALEFANNRSAKVITITDSIHSPMNLYSSCNLIADSDMA
HCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCEEECCHHH
SIVDSLVAPLSVINALIVALCMKKQNIVAKTLTELEDIWNEYQVYENDEIDYIDDSIKVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEECCCCEEE
YAKLGDSQDE
EEECCCCCCC
>Mature Secondary Structure
MMSNTNDLLNRINAKYSTMSKGHKLLATYITDNYDKAVFLTAAKMGETVGISESTVVRFA
CCCCHHHHHHHHCCHHHHHHCCHHEEEHHHCCCCCCEEEEEHHHCCCCCCCCHHHHHHHH
TSLGYKGYPDFQKALEELVRNKLNSVQRMEVTYGRISQSQILETVLQSDRDKIKTTLEKI
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHH
DADAFDLAVDTILQSRKIYIVGIRSCAPLASFLAFYMNLMFEDVCLLTTNSSSELFEQMV
CCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHH
RIGKDDVIIGISFPRYSMRTLKALEFANNRSAKVITITDSIHSPMNLYSSCNLIADSDMA
HCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCEEECCHHH
SIVDSLVAPLSVINALIVALCMKKQNIVAKTLTELEDIWNEYQVYENDEIDYIDDSIKVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEECCCCEEE
YAKLGDSQDE
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8177218; 11792842 [H]