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The map label for this gene is rnr [H]

Identifier: 238923910

GI number: 238923910

Start: 1420859

End: 1423009

Strand: Direct

Name: rnr [H]

Synonym: EUBREC_1538

Alternate gene names: 238923910

Gene position: 1420859-1423009 (Clockwise)

Preceding gene: 238923909

Following gene: 238923911

Centisome position: 41.19

GC content: 42.82

Gene sequence:

>2151_bases
ATGGGGCAACGAAAAGGAGAGATAATGAGTAATATAGATAAATATGAAACACGAAAAAAGATGGTCTATGACTTCATGTG
TGATGACATGTATGTTCCGATGAAAATCAAGGAACTTTGCATAGTACTAGGAGTAAAAAAAGAGGACAGACCTCAGCTTG
AACAGATTCTTTTGGATTTGCAGGCAGAGGGAAGGATAACACTCTCAAAGCGCGGGAAATATTCAAAGTCGGAAATCAAA
AAGACAGTCGGCGTATTCACAGCGCATCAAAGGGGATTTGGCTTTGTCACTGTGGAGGGAGAGCCTGATGATATTTTTAT
CCCGGCAGAGTATGTAAATGGTGCGATGCACATGGATACTGTTGAGATTACAATCTCACCTGTCACAACAGGACGCCGCA
AGGAGGGAAAGGTTGTTTCCGTCATAGAGCGAGGCATGAAGCAGGTAGTCTGCACCTATGAGGCAAGTGATAATTTTGGT
TTTGCAGTGCCTGACAATACCAGATTTGGCACAGATATTTTCATACCAAAGGAACGCTCAAAGGGTGCTATGTCGGGCCA
TAAGGTAGTGGTTGAAATCACAAGCTATGGTAAAAAGGGCAAAAAGCCGGAGGGCAAGGTTGTTGAAATAATCGGACATA
TAGATGACCCGGGTACAGATATTCTTTCTATAGTAAAGGCTTATGATCTGCCGGTGGATTTTTCGGAGAAAATCATGCAT
CAGGTGCAGAATGTGGCAAAGGATGTGACACCTGCGGATATGGCCGGCAGGATGGATTTACGCGACTGGATGATGGTCAC
GATAGACGGAGAGGATGCAAAGGATCTTGATGATGCCGTGTCTTTATACATGGATGGCGATAATTATGTACTTGGAGTAC
ACATAGCAGATGTGTCGAATTATGTGCAGGAGCACAGTGCCCTTGATGTGGAGGCTCTTAAGAGAGGAACATCGGTTTAT
CTTGTAGACAGAGTAATTCCTATGCTTCCAAGAGAGCTTTCAAATGGCATATGCTCCTTGAATGAGGGATGTGACAGGCT
GGCTCTTTCATGCATTATGACAATAAATAAAAAGGGTGAAGTTATCGATCATAAGATTGCAGAGACAGTCATAAAGACAA
ACCGCAGGATGACGTACACAAATGTAAAAAAGATTCTTGCAGATAAGGATGCCGCTGTGATTGAAGAATATAAGGAGCTT
GTGCCTATGTTTGAAAAAATGGCAGAGCTTGCAGCAATTCTACGCAAAAAGAGAATGAAACGGGGTTCTATAGACTTTGA
CTTTCCGGAGACTAAAGTCGTGCTCGATGAAGATGGTCATCCGATAGATATAAAGCCGTATGACAGAAATGTGGCAACAA
AGCTCATTGAGGATTTTATGCTTATAGCAAATGAAACTGTGGCTGAGGATTATTTCTGGCAGGAAATACCTTTTGTATAC
AGAACACATGACAAGCCAGACTCAGAAAAAATCGCAAAGCTTTCCACATTTATCAATAATTTTGGCTATACGCTTCATAT
TGGAGCTGATGAGGTACACCCAAAGGAGCTTCAGAAGCTTTTGATGAAGGTGGACGGCACAGACGAGGAATCGCTGATAA
GCAGACTGACACTGCGCTCTATGAAACAGGCACGATATACAACAGCATGTACAGGACATTTTGGACTGGCAGCGAATTAT
TATTGTCACTTTACATCACCAATCCGCAGATATCCTGATTTGCAGATACACCGTATCATCAAGGAAAATATCCGCGGCAG
GATGAATGATAACCGTAGGGAGCACTATGAGTCTATACTCGATGCTGTTGCAAAGCAGGCAAGTGAGACCGAACGACGTG
CAGAAGAGGCAGAGCGTGAAACAGTCAAGCTTAAAAAATGTGAATACATGTCAAATCATATTGGTGAATGCTTTGAAGGA
GTTATATCAGGTGTCACGGAGTGGGGCTTTTTCGTGGAGCTTCCAAATACAGTTGAGGGTCTTGTGCGCGTGACAGACCT
GACAGATGATTTCTATGAGTTTTACGAGGATACCTATGAGCTAGCCGGTACAGCCACCAATAAGAGATACAAGCTTGGAC
AAAAAATTAAGGTTGTTGTGGACAGTGCTGACAAAATTATGCGTACAATTGATTTTAAACCGGCGGAATAA

Upstream 100 bases:

>100_bases
GAGGTTTTCGTTGCAGGTTGATGTGATATAAAATCAACATTCATAGGATGAAAATGTCAATGGAGGAAATTTTATTTAAA
GTCTGTGCATTTGAAATCAG

Downstream 100 bases:

>100_bases
TATGACAATAATGACGAAATTTTTTTATGATTTAAAAATACTTATTTGATTATCTGTTATTTGTCGGTCGTTGTGCGATA
GATTTATTGAAAAAGATGTC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 716; Mature: 715

Protein sequence:

>716_residues
MGQRKGEIMSNIDKYETRKKMVYDFMCDDMYVPMKIKELCIVLGVKKEDRPQLEQILLDLQAEGRITLSKRGKYSKSEIK
KTVGVFTAHQRGFGFVTVEGEPDDIFIPAEYVNGAMHMDTVEITISPVTTGRRKEGKVVSVIERGMKQVVCTYEASDNFG
FAVPDNTRFGTDIFIPKERSKGAMSGHKVVVEITSYGKKGKKPEGKVVEIIGHIDDPGTDILSIVKAYDLPVDFSEKIMH
QVQNVAKDVTPADMAGRMDLRDWMMVTIDGEDAKDLDDAVSLYMDGDNYVLGVHIADVSNYVQEHSALDVEALKRGTSVY
LVDRVIPMLPRELSNGICSLNEGCDRLALSCIMTINKKGEVIDHKIAETVIKTNRRMTYTNVKKILADKDAAVIEEYKEL
VPMFEKMAELAAILRKKRMKRGSIDFDFPETKVVLDEDGHPIDIKPYDRNVATKLIEDFMLIANETVAEDYFWQEIPFVY
RTHDKPDSEKIAKLSTFINNFGYTLHIGADEVHPKELQKLLMKVDGTDEESLISRLTLRSMKQARYTTACTGHFGLAANY
YCHFTSPIRRYPDLQIHRIIKENIRGRMNDNRREHYESILDAVAKQASETERRAEEAERETVKLKKCEYMSNHIGECFEG
VISGVTEWGFFVELPNTVEGLVRVTDLTDDFYEFYEDTYELAGTATNKRYKLGQKIKVVVDSADKIMRTIDFKPAE

Sequences:

>Translated_716_residues
MGQRKGEIMSNIDKYETRKKMVYDFMCDDMYVPMKIKELCIVLGVKKEDRPQLEQILLDLQAEGRITLSKRGKYSKSEIK
KTVGVFTAHQRGFGFVTVEGEPDDIFIPAEYVNGAMHMDTVEITISPVTTGRRKEGKVVSVIERGMKQVVCTYEASDNFG
FAVPDNTRFGTDIFIPKERSKGAMSGHKVVVEITSYGKKGKKPEGKVVEIIGHIDDPGTDILSIVKAYDLPVDFSEKIMH
QVQNVAKDVTPADMAGRMDLRDWMMVTIDGEDAKDLDDAVSLYMDGDNYVLGVHIADVSNYVQEHSALDVEALKRGTSVY
LVDRVIPMLPRELSNGICSLNEGCDRLALSCIMTINKKGEVIDHKIAETVIKTNRRMTYTNVKKILADKDAAVIEEYKEL
VPMFEKMAELAAILRKKRMKRGSIDFDFPETKVVLDEDGHPIDIKPYDRNVATKLIEDFMLIANETVAEDYFWQEIPFVY
RTHDKPDSEKIAKLSTFINNFGYTLHIGADEVHPKELQKLLMKVDGTDEESLISRLTLRSMKQARYTTACTGHFGLAANY
YCHFTSPIRRYPDLQIHRIIKENIRGRMNDNRREHYESILDAVAKQASETERRAEEAERETVKLKKCEYMSNHIGECFEG
VISGVTEWGFFVELPNTVEGLVRVTDLTDDFYEFYEDTYELAGTATNKRYKLGQKIKVVVDSADKIMRTIDFKPAE
>Mature_715_residues
GQRKGEIMSNIDKYETRKKMVYDFMCDDMYVPMKIKELCIVLGVKKEDRPQLEQILLDLQAEGRITLSKRGKYSKSEIKK
TVGVFTAHQRGFGFVTVEGEPDDIFIPAEYVNGAMHMDTVEITISPVTTGRRKEGKVVSVIERGMKQVVCTYEASDNFGF
AVPDNTRFGTDIFIPKERSKGAMSGHKVVVEITSYGKKGKKPEGKVVEIIGHIDDPGTDILSIVKAYDLPVDFSEKIMHQ
VQNVAKDVTPADMAGRMDLRDWMMVTIDGEDAKDLDDAVSLYMDGDNYVLGVHIADVSNYVQEHSALDVEALKRGTSVYL
VDRVIPMLPRELSNGICSLNEGCDRLALSCIMTINKKGEVIDHKIAETVIKTNRRMTYTNVKKILADKDAAVIEEYKELV
PMFEKMAELAAILRKKRMKRGSIDFDFPETKVVLDEDGHPIDIKPYDRNVATKLIEDFMLIANETVAEDYFWQEIPFVYR
THDKPDSEKIAKLSTFINNFGYTLHIGADEVHPKELQKLLMKVDGTDEESLISRLTLRSMKQARYTTACTGHFGLAANYY
CHFTSPIRRYPDLQIHRIIKENIRGRMNDNRREHYESILDAVAKQASETERRAEEAERETVKLKKCEYMSNHIGECFEGV
ISGVTEWGFFVELPNTVEGLVRVTDLTDDFYEFYEDTYELAGTATNKRYKLGQKIKVVVDSADKIMRTIDFKPAE

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=470, Percent_Identity=29.7872340425532, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI190014623, Length=470, Percent_Identity=29.7872340425532, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI134288890, Length=418, Percent_Identity=31.5789473684211, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI219521928, Length=556, Percent_Identity=27.3381294964029, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI19115966, Length=556, Percent_Identity=27.3381294964029, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI156105695, Length=207, Percent_Identity=29.4685990338164, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI156105693, Length=195, Percent_Identity=30.2564102564103, Blast_Score=86, Evalue=2e-16,
Organism=Escherichia coli, GI87082383, Length=698, Percent_Identity=37.3925501432665, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1787542, Length=587, Percent_Identity=26.0647359454855, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI212645896, Length=551, Percent_Identity=28.3121597096189, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17553506, Length=501, Percent_Identity=29.1417165668663, Blast_Score=181, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6324552, Length=546, Percent_Identity=28.5714285714286, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320499, Length=413, Percent_Identity=23.9709443099274, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323943, Length=361, Percent_Identity=25.207756232687, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24649634, Length=484, Percent_Identity=29.7520661157025, Blast_Score=225, Evalue=8e-59,
Organism=Drosophila melanogaster, GI19922976, Length=469, Percent_Identity=28.997867803838, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24654597, Length=469, Percent_Identity=28.997867803838, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24654592, Length=469, Percent_Identity=28.997867803838, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 81483; Mature: 81352

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQRKGEIMSNIDKYETRKKMVYDFMCDDMYVPMKIKELCIVLGVKKEDRPQLEQILLDL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
QAEGRITLSKRGKYSKSEIKKTVGVFTAHQRGFGFVTVEGEPDDIFIPAEYVNGAMHMDT
CCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCEEEEEECCCCCEEEEHHHHCCEEEEEE
VEITISPVTTGRRKEGKVVSVIERGMKQVVCTYEASDNFGFAVPDNTRFGTDIFIPKERS
EEEEEEECCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCCEECCCCCCCCCEEEEECCCC
KGAMSGHKVVVEITSYGKKGKKPEGKVVEIIGHIDDPGTDILSIVKAYDLPVDFSEKIMH
CCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHH
QVQNVAKDVTPADMAGRMDLRDWMMVTIDGEDAKDLDDAVSLYMDGDNYVLGVHIADVSN
HHHHHHHCCCCHHHCCCCCCCCEEEEEECCCCCCCHHHHHEEEECCCCEEEEEEEHHHHH
YVQEHSALDVEALKRGTSVYLVDRVIPMLPRELSNGICSLNEGCDRLALSCIMTINKKGE
HHHHHCCCCHHHHHCCCEEEEHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC
VIDHKIAETVIKTNRRMTYTNVKKILADKDAAVIEEYKELVPMFEKMAELAAILRKKRMK
HHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGSIDFDFPETKVVLDEDGHPIDIKPYDRNVATKLIEDFMLIANETVAEDYFWQEIPFVY
CCCCCCCCCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEE
RTHDKPDSEKIAKLSTFINNFGYTLHIGADEVHPKELQKLLMKVDGTDEESLISRLTLRS
ECCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
MKQARYTTACTGHFGLAANYYCHFTSPIRRYPDLQIHRIIKENIRGRMNDNRREHYESIL
HHHHHHHEEECCCCCCEECEEEEECCHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
DAVAKQASETERRAEEAERETVKLKKCEYMSNHIGECFEGVISGVTEWGFFVELPNTVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
LVRVTDLTDDFYEFYEDTYELAGTATNKRYKLGQKIKVVVDSADKIMRTIDFKPAE
HEEHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCC
>Mature Secondary Structure 
GQRKGEIMSNIDKYETRKKMVYDFMCDDMYVPMKIKELCIVLGVKKEDRPQLEQILLDL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
QAEGRITLSKRGKYSKSEIKKTVGVFTAHQRGFGFVTVEGEPDDIFIPAEYVNGAMHMDT
CCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCEEEEEECCCCCEEEEHHHHCCEEEEEE
VEITISPVTTGRRKEGKVVSVIERGMKQVVCTYEASDNFGFAVPDNTRFGTDIFIPKERS
EEEEEEECCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCCEECCCCCCCCCEEEEECCCC
KGAMSGHKVVVEITSYGKKGKKPEGKVVEIIGHIDDPGTDILSIVKAYDLPVDFSEKIMH
CCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHH
QVQNVAKDVTPADMAGRMDLRDWMMVTIDGEDAKDLDDAVSLYMDGDNYVLGVHIADVSN
HHHHHHHCCCCHHHCCCCCCCCEEEEEECCCCCCCHHHHHEEEECCCCEEEEEEEHHHHH
YVQEHSALDVEALKRGTSVYLVDRVIPMLPRELSNGICSLNEGCDRLALSCIMTINKKGE
HHHHHCCCCHHHHHCCCEEEEHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC
VIDHKIAETVIKTNRRMTYTNVKKILADKDAAVIEEYKELVPMFEKMAELAAILRKKRMK
HHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGSIDFDFPETKVVLDEDGHPIDIKPYDRNVATKLIEDFMLIANETVAEDYFWQEIPFVY
CCCCCCCCCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEE
RTHDKPDSEKIAKLSTFINNFGYTLHIGADEVHPKELQKLLMKVDGTDEESLISRLTLRS
ECCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
MKQARYTTACTGHFGLAANYYCHFTSPIRRYPDLQIHRIIKENIRGRMNDNRREHYESIL
HHHHHHHEEECCCCCCEECEEEEECCHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
DAVAKQASETERRAEEAERETVKLKKCEYMSNHIGECFEGVISGVTEWGFFVELPNTVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
LVRVTDLTDDFYEFYEDTYELAGTATNKRYKLGQKIKVVVDSADKIMRTIDFKPAE
HEEHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]