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The map label for this gene is yacO [H]

Identifier: 238923821

GI number: 238923821

Start: 1327944

End: 1328711

Strand: Direct

Name: yacO [H]

Synonym: EUBREC_1448

Alternate gene names: 238923821

Gene position: 1327944-1328711 (Clockwise)

Preceding gene: 238923820

Following gene: 238923822

Centisome position: 38.49

GC content: 44.92

Gene sequence:

>768_bases
ATGGATAACAACAATAAAGAAAAATTTCATGAGAATTATATAGAGGGCAGAAATGCTGTGCTGGAGGCTTTCCGTTCGGG
AAAGACAATAGACAAGCTTTTTGTGCTTGACGGCTGTCAGGACGGACCAATAAAGTCAATCACAAGAGAGGCCAGAAAGC
ATGATGCAATCATAAACTATGTTGCAAAGGAAAGACTTGATCAGATGTCTGAGACAGGCAAGCATCAGGGTGTCATTGCA
GTTTCAGCAGCATATGAGTATGCCGAGGTTTCGGACATACTGGAAAATGCCGAAAGGAAGGGCGAGCCGCCTTTTATCAT
CATACTTGACGGTATAGAGGATCCACACAATCTTGGCGCAATAATCCGTACCGCAAATCAGGCGGGTGCACATGGCATCA
TCATACCAAAAAGGCGTGCAGTGGGACTTACCCCTACAGTGGCAAAGACGTCTGCAGGTGCGATAAACTATACACCTGTT
GCCAAGGTTACCAATATCTCAAATACCATAAAGGAGCTTAAGGAAAAGGGTATGTGGTTTGTATGTGCTGATATGGGTGG
CACTACAATGTATGACTTAAACCTCACAGGTCCTATAGGTCTTGTCATAGGCAATGAGGGTGACGGAGTCAGCAAGCTTG
TAAAGGAAAACTGTGATATGACAGCTTCTATTCCTATGGTGGGCGATATTGACTCACTGAACGCATCGGTTGCGACAGGC
GTGCTTGCATATGAGATAGTCAGACAGAGACTTAAGAGTGGAAAGTAG

Upstream 100 bases:

>100_bases
TATCTTTATCTGAAGGATGATTTTGAGAGGGTTGTTTCACTCACTAAGCTTGGAGTGGAGCTTTTAGGAATTGAAATATA
GCACAAAATAAGAGGAAAAT

Downstream 100 bases:

>100_bases
ATTGCATGTCGCTGGATGAGTGGTGTATTATGAATTGTATATTTATAGAATAGGAAGCATATAGTGGAAGATTACAGCGC
ATATACGGATGAAGAGCTTA

Product: putative tRNA/rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDNNNKEKFHENYIEGRNAVLEAFRSGKTIDKLFVLDGCQDGPIKSITREARKHDAIINYVAKERLDQMSETGKHQGVIA
VSAAYEYAEVSDILENAERKGEPPFIIILDGIEDPHNLGAIIRTANQAGAHGIIIPKRRAVGLTPTVAKTSAGAINYTPV
AKVTNISNTIKELKEKGMWFVCADMGGTTMYDLNLTGPIGLVIGNEGDGVSKLVKENCDMTASIPMVGDIDSLNASVATG
VLAYEIVRQRLKSGK

Sequences:

>Translated_255_residues
MDNNNKEKFHENYIEGRNAVLEAFRSGKTIDKLFVLDGCQDGPIKSITREARKHDAIINYVAKERLDQMSETGKHQGVIA
VSAAYEYAEVSDILENAERKGEPPFIIILDGIEDPHNLGAIIRTANQAGAHGIIIPKRRAVGLTPTVAKTSAGAINYTPV
AKVTNISNTIKELKEKGMWFVCADMGGTTMYDLNLTGPIGLVIGNEGDGVSKLVKENCDMTASIPMVGDIDSLNASVATG
VLAYEIVRQRLKSGK
>Mature_255_residues
MDNNNKEKFHENYIEGRNAVLEAFRSGKTIDKLFVLDGCQDGPIKSITREARKHDAIINYVAKERLDQMSETGKHQGVIA
VSAAYEYAEVSDILENAERKGEPPFIIILDGIEDPHNLGAIIRTANQAGAHGIIIPKRRAVGLTPTVAKTSAGAINYTPV
AKVTNISNTIKELKEKGMWFVCADMGGTTMYDLNLTGPIGLVIGNEGDGVSKLVKENCDMTASIPMVGDIDSLNASVATG
VLAYEIVRQRLKSGK

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=229, Percent_Identity=29.6943231441048, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1790623, Length=241, Percent_Identity=37.7593360995851, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1790083, Length=172, Percent_Identity=28.4883720930233, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788935, Length=246, Percent_Identity=23.5772357723577, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555908, Length=255, Percent_Identity=29.0196078431373, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324775, Length=164, Percent_Identity=36.5853658536585, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27601; Mature: 27601

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNNKEKFHENYIEGRNAVLEAFRSGKTIDKLFVLDGCQDGPIKSITREARKHDAIINY
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
VAKERLDQMSETGKHQGVIAVSAAYEYAEVSDILENAERKGEPPFIIILDGIEDPHNLGA
HHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
IIRTANQAGAHGIIIPKRRAVGLTPTVAKTSAGAINYTPVAKVTNISNTIKELKEKGMWF
HHEECCCCCCCEEEECCCCCCCCCCCHHCCCCCCEECCCCHHHHHHHHHHHHHHHCCCEE
VCADMGGTTMYDLNLTGPIGLVIGNEGDGVSKLVKENCDMTASIPMVGDIDSLNASVATG
EEECCCCCEEEEEEECCCEEEEECCCCCCHHHHHHCCCCCEECCCCCCCCHHCCHHHHHH
VLAYEIVRQRLKSGK
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MDNNNKEKFHENYIEGRNAVLEAFRSGKTIDKLFVLDGCQDGPIKSITREARKHDAIINY
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
VAKERLDQMSETGKHQGVIAVSAAYEYAEVSDILENAERKGEPPFIIILDGIEDPHNLGA
HHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
IIRTANQAGAHGIIIPKRRAVGLTPTVAKTSAGAINYTPVAKVTNISNTIKELKEKGMWF
HHEECCCCCCCEEEECCCCCCCCCCCHHCCCCCCEECCCCHHHHHHHHHHHHHHHCCCEE
VCADMGGTTMYDLNLTGPIGLVIGNEGDGVSKLVKENCDMTASIPMVGDIDSLNASVATG
EEECCCCCEEEEEEECCCEEEEECCCCCCHHHHHHCCCCCEECCCCCCCCHHCCHHHHHH
VLAYEIVRQRLKSGK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]