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The map label for this gene is cysS [H]

Identifier: 238923819

GI number: 238923819

Start: 1326067

End: 1327494

Strand: Direct

Name: cysS [H]

Synonym: EUBREC_1446

Alternate gene names: 238923819

Gene position: 1326067-1327494 (Clockwise)

Preceding gene: 238923818

Following gene: 238923820

Centisome position: 38.44

GC content: 45.66

Gene sequence:

>1428_bases
ATGGAGAACAATTTCAAGTTTTACAATACACTCACAAGACAGATTGATACTGTTGTTCCGCGTGTTGACGGCAAAATCGG
CATGTATACATGTGGACCTACAGTTTACCATTTTGCACATATCGGAAATATCCGCTCATACATCATGGAGGATGTGCTTG
AGAAGGCACTTCGCTATGTGGGCTATGATGTAAAGCGTGTCATGAATATCACTGATGTGGGACATCTCTCAAGCGACGGA
GATACCGGAGAGGACAAGATGCTAAAGGGCGCAAAGCGTGAGCATAAGAGCGTCATGGAGGTGGCAAAGGAGTACACGGA
CGCCTTTTTCAAGGATTTCACGGCTGTACACAACAGGATGCCTGATGTCGTAGAGCCTGCAACCAACTGTATTCCGGAAT
TCATCCATATGGTGGAGGTGCTTATCGAGAAGGGCTATGCCTATTTTGCCGGAGGCAATGTATATTTCGATACATCAAAG
CTTGATGATTATTTTGTGTTCTCTTCAGCAGTAGAGAAGGAACAGCTTCAGGTTGGAGTGCGAGATGATGTCGAGGAGGA
TGTAAACAAGAAGAATAAAAATGATTTCGTACTCTGGTTTACACAGTCTAAGTTTGAGGACCAGGCTCTTAAATGGGACA
GCCCATGGGGCGTCGGATATCCGGGCTGGCATATAGAGTGCTCATGCATCAGCATGAAGCATCTCGGAGAGTACGTGGAT
ATCCACTGTGGCGGTGTGGACAATATTTTCCCACATCACACCAATGAGATTGCACAGTCAGAGAGCTATCTGGGACACGA
CTGGTGCAAGTACTGGTTCCATGTCAATCACTTAAATGACAGAGCCGGCAAGATGAGCAAGTCGAAGGGGGCAATCCTCA
CAGTTTCGGTGCTTCAGGAGAAGGGCTACAATCCGCTTGCCTACAGATTCTTCTGCTTACAGTCACACTACAGAAAGCCT
CTTGAGTTTTCGTTTGATGCGCTCGACAATGCAGTTGCGGCATACAATAAGATTGCAAAGCGTGTGGCAGAGCTTAAGGA
TGAGGGTGATATAGATGAGACAGCTTTTGCTGACTTTAAGAAGAAATTTACTGATGCAGTTTCAAATGATCTGAATACAT
CAATGGCTATAACCATAGTGTATGATGTGCTTAAGGCTGATATCTCAGACAGGACAAAGCTTGCACTTATCGATGACTTT
GAGCAGGTACTTGATCTGGGACTTAGGGAATCAGGAAAGGCCTTACTTGAGGCATCGTCATCTGTAGACAGTGAGCTTGA
GGCATTTATCAATGATAAAATTGCAGAGCGTGCAGCCGCTAAAAAGGCAAAGGATTTTGCGACAGCCGATGCCATAAGAG
ATGAGCTTCTGGCAAGGGGGGTTGCCATAAAGGATACCAGAGAGGGAGTAAAATGGGAGCTTGTATAG

Upstream 100 bases:

>100_bases
AGCGGCTGCGGAGGCTGTCAGGCCGATTGATTTGAATATATAGGGAAAACATGCTAAAATAAAAAGATAGTTATAAATCA
TCCAAAAGGAGATATAAATA

Downstream 100 bases:

>100_bases
TATGAAGATAGACTCATATATTAAGGAACAGTTTGGAATAAAGGACGTTGATATAAGGACATACTCGCCGCTTACACTTG
CATATATCGGTGATGGCATA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MENNFKFYNTLTRQIDTVVPRVDGKIGMYTCGPTVYHFAHIGNIRSYIMEDVLEKALRYVGYDVKRVMNITDVGHLSSDG
DTGEDKMLKGAKREHKSVMEVAKEYTDAFFKDFTAVHNRMPDVVEPATNCIPEFIHMVEVLIEKGYAYFAGGNVYFDTSK
LDDYFVFSSAVEKEQLQVGVRDDVEEDVNKKNKNDFVLWFTQSKFEDQALKWDSPWGVGYPGWHIECSCISMKHLGEYVD
IHCGGVDNIFPHHTNEIAQSESYLGHDWCKYWFHVNHLNDRAGKMSKSKGAILTVSVLQEKGYNPLAYRFFCLQSHYRKP
LEFSFDALDNAVAAYNKIAKRVAELKDEGDIDETAFADFKKKFTDAVSNDLNTSMAITIVYDVLKADISDRTKLALIDDF
EQVLDLGLRESGKALLEASSSVDSELEAFINDKIAERAAAKKAKDFATADAIRDELLARGVAIKDTREGVKWELV

Sequences:

>Translated_475_residues
MENNFKFYNTLTRQIDTVVPRVDGKIGMYTCGPTVYHFAHIGNIRSYIMEDVLEKALRYVGYDVKRVMNITDVGHLSSDG
DTGEDKMLKGAKREHKSVMEVAKEYTDAFFKDFTAVHNRMPDVVEPATNCIPEFIHMVEVLIEKGYAYFAGGNVYFDTSK
LDDYFVFSSAVEKEQLQVGVRDDVEEDVNKKNKNDFVLWFTQSKFEDQALKWDSPWGVGYPGWHIECSCISMKHLGEYVD
IHCGGVDNIFPHHTNEIAQSESYLGHDWCKYWFHVNHLNDRAGKMSKSKGAILTVSVLQEKGYNPLAYRFFCLQSHYRKP
LEFSFDALDNAVAAYNKIAKRVAELKDEGDIDETAFADFKKKFTDAVSNDLNTSMAITIVYDVLKADISDRTKLALIDDF
EQVLDLGLRESGKALLEASSSVDSELEAFINDKIAERAAAKKAKDFATADAIRDELLARGVAIKDTREGVKWELV
>Mature_475_residues
MENNFKFYNTLTRQIDTVVPRVDGKIGMYTCGPTVYHFAHIGNIRSYIMEDVLEKALRYVGYDVKRVMNITDVGHLSSDG
DTGEDKMLKGAKREHKSVMEVAKEYTDAFFKDFTAVHNRMPDVVEPATNCIPEFIHMVEVLIEKGYAYFAGGNVYFDTSK
LDDYFVFSSAVEKEQLQVGVRDDVEEDVNKKNKNDFVLWFTQSKFEDQALKWDSPWGVGYPGWHIECSCISMKHLGEYVD
IHCGGVDNIFPHHTNEIAQSESYLGHDWCKYWFHVNHLNDRAGKMSKSKGAILTVSVLQEKGYNPLAYRFFCLQSHYRKP
LEFSFDALDNAVAAYNKIAKRVAELKDEGDIDETAFADFKKKFTDAVSNDLNTSMAITIVYDVLKADISDRTKLALIDDF
EQVLDLGLRESGKALLEASSSVDSELEAFINDKIAERAAAKKAKDFATADAIRDELLARGVAIKDTREGVKWELV

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=493, Percent_Identity=31.0344827586207, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI62240992, Length=235, Percent_Identity=34.468085106383, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI10835051, Length=235, Percent_Identity=34.468085106383, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI303304987, Length=235, Percent_Identity=34.468085106383, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI21269877, Length=235, Percent_Identity=34.468085106383, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1786737, Length=478, Percent_Identity=37.6569037656904, Blast_Score=256, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17509795, Length=259, Percent_Identity=34.3629343629344, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17509797, Length=259, Percent_Identity=34.3629343629344, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324082, Length=315, Percent_Identity=32.3809523809524, Blast_Score=143, Evalue=6e-35,
Organism=Drosophila melanogaster, GI19922218, Length=519, Percent_Identity=30.4431599229287, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI19922364, Length=298, Percent_Identity=32.8859060402685, Blast_Score=148, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53903; Mature: 53903

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNFKFYNTLTRQIDTVVPRVDGKIGMYTCGPTVYHFAHIGNIRSYIMEDVLEKALRYV
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYDVKRVMNITDVGHLSSDGDTGEDKMLKGAKREHKSVMEVAKEYTDAFFKDFTAVHNRM
CHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDVVEPATNCIPEFIHMVEVLIEKGYAYFAGGNVYFDTSKLDDYFVFSSAVEKEQLQVGV
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCHHHHHHHHHHHHHHHCCC
RDDVEEDVNKKNKNDFVLWFTQSKFEDQALKWDSPWGVGYPGWHIECSCISMKHLGEYVD
CCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHCCCEEE
IHCGGVDNIFPHHTNEIAQSESYLGHDWCKYWFHVNHLNDRAGKMSKSKGAILTVSVLQE
EEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEHHH
KGYNPLAYRFFCLQSHYRKPLEFSFDALDNAVAAYNKIAKRVAELKDEGDIDETAFADFK
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KKFTDAVSNDLNTSMAITIVYDVLKADISDRTKLALIDDFEQVLDLGLRESGKALLEASS
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHC
SVDSELEAFINDKIAERAAAKKAKDFATADAIRDELLARGVAIKDTREGVKWELV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEECC
>Mature Secondary Structure
MENNFKFYNTLTRQIDTVVPRVDGKIGMYTCGPTVYHFAHIGNIRSYIMEDVLEKALRYV
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYDVKRVMNITDVGHLSSDGDTGEDKMLKGAKREHKSVMEVAKEYTDAFFKDFTAVHNRM
CHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDVVEPATNCIPEFIHMVEVLIEKGYAYFAGGNVYFDTSKLDDYFVFSSAVEKEQLQVGV
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCHHHHHHHHHHHHHHHCCC
RDDVEEDVNKKNKNDFVLWFTQSKFEDQALKWDSPWGVGYPGWHIECSCISMKHLGEYVD
CCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHCCCEEE
IHCGGVDNIFPHHTNEIAQSESYLGHDWCKYWFHVNHLNDRAGKMSKSKGAILTVSVLQE
EEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEHHH
KGYNPLAYRFFCLQSHYRKPLEFSFDALDNAVAAYNKIAKRVAELKDEGDIDETAFADFK
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KKFTDAVSNDLNTSMAITIVYDVLKADISDRTKLALIDDFEQVLDLGLRESGKALLEASS
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHC
SVDSELEAFINDKIAERAAAKKAKDFATADAIRDELLARGVAIKDTREGVKWELV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA