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The map label for this gene is nrdR

Identifier: 238923806

GI number: 238923806

Start: 1313424

End: 1313879

Strand: Direct

Name: nrdR

Synonym: EUBREC_1429

Alternate gene names: 238923806

Gene position: 1313424-1313879 (Clockwise)

Preceding gene: 238923805

Following gene: 238923807

Centisome position: 38.07

GC content: 43.2

Gene sequence:

>456_bases
ATGAAGTGTCCATTTTGCAGTAGTGACAACACAAGGGTAATAGACTCAAGACCGGCTGATGACAACAGCTCTATCAGGCG
CAGAAGGCTGTGCGATGATTGCGGCAAGCGTTTCACTACATATGAGAAGGTGGAGACAATCCCGCTCATCGTTATAAAAA
AGGACAACAACAGAGAGCAGTATGACCGCTCCAAGATTGAAAAGGGCGTGCTTCTTGCATGTCACAAGAGACCGATTTCA
GCAGATACAATCTCAAAGCTTGTAGATGAGGTCGAGATAGAAATCTTTGCCAGAGAGGAAAAGGAAATCTCTACATCACT
CATCGGAGAGTTGATTATGGACAGATTAAAGGACCTTGATGCGGTAGCATATGTGAGGTTTGCGTCAGTTTACAGAGAGT
TTAAGGATGTCAATACATTTATGACAGAGCTTAAAAAGATGCTTGACACCAAATAG

Upstream 100 bases:

>100_bases
TATAGGTCTTTTTAAATACAGATGATGATTTGAAGTATTATAATGAGAAACAAAGATATTTTGCTTCTTCATACTATATG
ATACCTACGGAGGGTACAGC

Downstream 100 bases:

>100_bases
TGTTTAGGCAGCAGGATTTATTTAAAACAGGATGGGAAGGTGCGTATGAACATTTCCGGTATTCGCCCGAGCGAAGGCTT
TTATTCATACAATTCCATAA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKCPFCSSDNTRVIDSRPADDNSSIRRRRLCDDCGKRFTTYEKVETIPLIVIKKDNNREQYDRSKIEKGVLLACHKRPIS
ADTISKLVDEVEIEIFAREEKEISTSLIGELIMDRLKDLDAVAYVRFASVYREFKDVNTFMTELKKMLDTK

Sequences:

>Translated_151_residues
MKCPFCSSDNTRVIDSRPADDNSSIRRRRLCDDCGKRFTTYEKVETIPLIVIKKDNNREQYDRSKIEKGVLLACHKRPIS
ADTISKLVDEVEIEIFAREEKEISTSLIGELIMDRLKDLDAVAYVRFASVYREFKDVNTFMTELKKMLDTK
>Mature_151_residues
MKCPFCSSDNTRVIDSRPADDNSSIRRRRLCDDCGKRFTTYEKVETIPLIVIKKDNNREQYDRSKIEKGVLLACHKRPIS
ADTISKLVDEVEIEIFAREEKEISTSLIGELIMDRLKDLDAVAYVRFASVYREFKDVNTFMTELKKMLDTK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=42.9530201342282, Blast_Score=138, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_EUBR3 (C4Z8V7)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002937322.1
- GeneID:   7963799
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_1429
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17576; Mature: 17576

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCSSDNTRVIDSRPADDNSSIRRRRLCDDCGKRFTTYEKVETIPLIVIKKDNNREQ
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHH
YDRSKIEKGVLLACHKRPISADTISKLVDEVEIEIFAREEKEISTSLIGELIMDRLKDLD
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAYVRFASVYREFKDVNTFMTELKKMLDTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKCPFCSSDNTRVIDSRPADDNSSIRRRRLCDDCGKRFTTYEKVETIPLIVIKKDNNREQ
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHH
YDRSKIEKGVLLACHKRPISADTISKLVDEVEIEIFAREEKEISTSLIGELIMDRLKDLD
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAYVRFASVYREFKDVNTFMTELKKMLDTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA