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The map label for this gene is ynaJ [H]

Identifier: 238923790

GI number: 238923790

Start: 1293130

End: 1294494

Strand: Direct

Name: ynaJ [H]

Synonym: EUBREC_1412

Alternate gene names: 238923790

Gene position: 1293130-1294494 (Clockwise)

Preceding gene: 238923789

Following gene: 238923791

Centisome position: 37.49

GC content: 38.39

Gene sequence:

>1365_bases
ATGAGTAGCGAAAACAAAAATGGAAAAGTACCGCTGATCAGTAAGATTGCATATGGGTTTGGTGATGTTGGATGTAATTT
CAGCTGGATGTTCGTCAGCAATTTTCTGATGATATTTTATACAGACGTGTTCGGAATCAGTATGGCGGCTGTGTCAGCAC
TTATGCTTTTTTCAAGATTCTGGGATGCAATCAATGATCCAATTGTCGGGGGACTTACGGATAAAACAAAATCGAGATGG
GGACGGTACCGTCCATGGCTGTTAGTAGCGGCACCAATTACAGCAATCCTTCTTGTTATGACATTCTGGGCAAGACCAGA
CTGGCCACAGAATGGAAAAATCATTTATATGGTAATTACATATTGTCTGCTGGTTTTGGGGTATACCTGTGTGAATATTC
CATATGGAACCTTGTGTGGTGCTATGACACAGGATATTGATGAACGTGCAAAAATAAATACATCCCGTTCGGTTGCAGCT
ATGATTGCAATTGGTGTGTTAAATATTATCACAGTTCCACTGCTCAGCAAATTCGGCAGTCACAGTGCAAAGGTAGGATA
TCTGACGGTTGCGGTCATATATGGATGTATTTTTACAGCCTGTCATTTCTTCTGCTTTGCGAAGACGAAAGAGGCAGTGA
TTATTCCGGAAAAAGAAAAAATTTCTGTGAAGGTACAGTTGAAAGCAGTCATGCAGAACAGACCATATCTTCTTGCATTG
GCAGGACAGATATTATTTGGATTTACATTATATGGTAGAAACGCAGATATTCTGTATTATTTTACATATGTGGAAGGAAA
TGCCTCCTACTACACAACTTATTCGATGTGCATCATTATTCCTTCTATCATAGGGGCAGCCTGTTTTCAACCATTATTCC
GCAAGTTGAATAACAAAGGAAGAACAGCATCTCTCTTTGCTTTATTTACAGGAATTTCCATGTTGTCTATGTTTTTCTTT
AATGCCAAAGAATCACCGGCTGTTTTTTATGCATTATCAGGTCTCACACAGTTTTTTTTCTCAGGATTTAATACTGCAAT
CTATGCAATTATTCCAGACTGTGTGGAATATGGGGAGTGGAAAACCGGACTTAGAAATGACGGTTTTCAGTATGCATTTA
TTTCACTTGGAAATAAAATCGGAATGGCAGTTGGAACAGCACTTTTAGCAGGATTACTTGGAAAATGTGGTTATATTGCA
AATCAGACACAAAATGCAACTGTACTTTCAATTATGAAACATGCATTTACGACGATTCCAGGTGCACTTTGGATTGTGAC
TGCGGTTGTATTATTTTTCTACCGGTTAAATAAAAAACGTTATAACGAGATTGTGGAGGAACTGAAAAATGGAAGAAAAA
GTTGA

Upstream 100 bases:

>100_bases
TCCATTTTGGGAAAAGGGTGTGAAGTTTTTTATGATTAAGGGACCAAATGAGGAAAGAATAGAGTTTTGTCAGAAACTCT
GATAAAAATAGGAGGGACAT

Downstream 100 bases:

>100_bases
TATTGTGGCATTGGGGGAATTACTGATTGATTTTACGGAAGCAGGACACAGTCAGGGTGGGAGAAAACTGTTTGAACAGA
ATCCCGGTGGTGCTCCGGCA

Product: glucuronide permease

Products: Proton [Cytoplasm]; Glucuronides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSSENKNGKVPLISKIAYGFGDVGCNFSWMFVSNFLMIFYTDVFGISMAAVSALMLFSRFWDAINDPIVGGLTDKTKSRW
GRYRPWLLVAAPITAILLVMTFWARPDWPQNGKIIYMVITYCLLVLGYTCVNIPYGTLCGAMTQDIDERAKINTSRSVAA
MIAIGVLNIITVPLLSKFGSHSAKVGYLTVAVIYGCIFTACHFFCFAKTKEAVIIPEKEKISVKVQLKAVMQNRPYLLAL
AGQILFGFTLYGRNADILYYFTYVEGNASYYTTYSMCIIIPSIIGAACFQPLFRKLNNKGRTASLFALFTGISMLSMFFF
NAKESPAVFYALSGLTQFFFSGFNTAIYAIIPDCVEYGEWKTGLRNDGFQYAFISLGNKIGMAVGTALLAGLLGKCGYIA
NQTQNATVLSIMKHAFTTIPGALWIVTAVVLFFYRLNKKRYNEIVEELKNGRKS

Sequences:

>Translated_454_residues
MSSENKNGKVPLISKIAYGFGDVGCNFSWMFVSNFLMIFYTDVFGISMAAVSALMLFSRFWDAINDPIVGGLTDKTKSRW
GRYRPWLLVAAPITAILLVMTFWARPDWPQNGKIIYMVITYCLLVLGYTCVNIPYGTLCGAMTQDIDERAKINTSRSVAA
MIAIGVLNIITVPLLSKFGSHSAKVGYLTVAVIYGCIFTACHFFCFAKTKEAVIIPEKEKISVKVQLKAVMQNRPYLLAL
AGQILFGFTLYGRNADILYYFTYVEGNASYYTTYSMCIIIPSIIGAACFQPLFRKLNNKGRTASLFALFTGISMLSMFFF
NAKESPAVFYALSGLTQFFFSGFNTAIYAIIPDCVEYGEWKTGLRNDGFQYAFISLGNKIGMAVGTALLAGLLGKCGYIA
NQTQNATVLSIMKHAFTTIPGALWIVTAVVLFFYRLNKKRYNEIVEELKNGRKS
>Mature_453_residues
SSENKNGKVPLISKIAYGFGDVGCNFSWMFVSNFLMIFYTDVFGISMAAVSALMLFSRFWDAINDPIVGGLTDKTKSRWG
RYRPWLLVAAPITAILLVMTFWARPDWPQNGKIIYMVITYCLLVLGYTCVNIPYGTLCGAMTQDIDERAKINTSRSVAAM
IAIGVLNIITVPLLSKFGSHSAKVGYLTVAVIYGCIFTACHFFCFAKTKEAVIIPEKEKISVKVQLKAVMQNRPYLLALA
GQILFGFTLYGRNADILYYFTYVEGNASYYTTYSMCIIIPSIIGAACFQPLFRKLNNKGRTASLFALFTGISMLSMFFFN
AKESPAVFYALSGLTQFFFSGFNTAIYAIIPDCVEYGEWKTGLRNDGFQYAFISLGNKIGMAVGTALLAGLLGKCGYIAN
QTQNATVLSIMKHAFTTIPGALWIVTAVVLFFYRLNKKRYNEIVEELKNGRKS

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI42713696, Length=299, Percent_Identity=24.7491638795987, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI211063479, Length=312, Percent_Identity=24.0384615384615, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787902, Length=456, Percent_Identity=29.6052631578947, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786466, Length=447, Percent_Identity=30.6487695749441, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87082306, Length=448, Percent_Identity=30.8035714285714, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1790561, Length=467, Percent_Identity=26.7665952890792, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI48994989, Length=471, Percent_Identity=29.2993630573248, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI145693206, Length=459, Percent_Identity=26.5795206971678, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50484; Mature: 50353

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSENKNGKVPLISKIAYGFGDVGCNFSWMFVSNFLMIFYTDVFGISMAAVSALMLFSRF
CCCCCCCCCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WDAINDPIVGGLTDKTKSRWGRYRPWLLVAAPITAILLVMTFWARPDWPQNGKIIYMVIT
HHHHCCCCCCCCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHH
YCLLVLGYTCVNIPYGTLCGAMTQDIDERAKINTSRSVAAMIAIGVLNIITVPLLSKFGS
HHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
HSAKVGYLTVAVIYGCIFTACHFFCFAKTKEAVIIPEKEKISVKVQLKAVMQNRPYLLAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEHHHCCCCEEEEE
AGQILFGFTLYGRNADILYYFTYVEGNASYYTTYSMCIIIPSIIGAACFQPLFRKLNNKG
HHHHHHHEEEECCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RTASLFALFTGISMLSMFFFNAKESPAVFYALSGLTQFFFSGFNTAIYAIIPDCVEYGEW
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEHEEHHHHHCCCC
KTGLRNDGFQYAFISLGNKIGMAVGTALLAGLLGKCGYIANQTQNATVLSIMKHAFTTIP
CCCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCC
GALWIVTAVVLFFYRLNKKRYNEIVEELKNGRKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSENKNGKVPLISKIAYGFGDVGCNFSWMFVSNFLMIFYTDVFGISMAAVSALMLFSRF
CCCCCCCCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WDAINDPIVGGLTDKTKSRWGRYRPWLLVAAPITAILLVMTFWARPDWPQNGKIIYMVIT
HHHHCCCCCCCCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHH
YCLLVLGYTCVNIPYGTLCGAMTQDIDERAKINTSRSVAAMIAIGVLNIITVPLLSKFGS
HHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
HSAKVGYLTVAVIYGCIFTACHFFCFAKTKEAVIIPEKEKISVKVQLKAVMQNRPYLLAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEHHHCCCCEEEEE
AGQILFGFTLYGRNADILYYFTYVEGNASYYTTYSMCIIIPSIIGAACFQPLFRKLNNKG
HHHHHHHEEEECCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RTASLFALFTGISMLSMFFFNAKESPAVFYALSGLTQFFFSGFNTAIYAIIPDCVEYGEW
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEHEEHHHHHCCCC
KTGLRNDGFQYAFISLGNKIGMAVGTALLAGLLGKCGYIANQTQNATVLSIMKHAFTTIP
CCCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCC
GALWIVTAVVLFFYRLNKKRYNEIVEELKNGRKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Glucuronides [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Glucuronides [Periplasm] = Proton [Cytoplasm] + Glucuronides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]