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The map label for this gene is lacG [H]

Identifier: 238923762

GI number: 238923762

Start: 1258787

End: 1259617

Strand: Direct

Name: lacG [H]

Synonym: EUBREC_1384

Alternate gene names: 238923762

Gene position: 1258787-1259617 (Clockwise)

Preceding gene: 238923761

Following gene: 238923763

Centisome position: 36.49

GC content: 41.52

Gene sequence:

>831_bases
GTGACTAAGAAAAAACATGGATCATCAATACAAAAAAGGCTTATACCTTCATACATTTTTCTTGTAATAGTTTCGTTCAT
CTCAGTATTTCCGTTTTTCTGGATGATATCGGCAGCGACCAACAAGTCTATTGACATTGCAAGAGGTAGAATTGCATTTG
GTGGCTATGCCCTTGAGAACTTAAAGAAACTGTTTGCATCACAGAACGTTGCACTTGGAATGAAAAACTCACTTATCAAT
GCAACAGTTCAGACAATTATAGCACTGCTTGTCTGCTCACTTGCCGGTTACGGCTTTGAGCTCTATCATGACAAGGCAAA
GGATAAGCTGTTCTCAGTTTTACTTCTTGCCATGATGATTCCGCAGGTAGCTACACTTATTCCTCTGTTCAAGATGATGT
CAAAGCTCGGCTTTATAAATACGGTATGGGGCTTCATGCTCCCGGCTATTTCAACGCCGTTCCTCATCATGATGTTCAGA
CAGAATTCGAGAAACTTCCCAGTCGATATAATGGAGGCGGCACGAATTGACGGACTCAGTGAGATTGGTATTTTCTTCAA
GATGTATATGCCTGTACAGAAATCAACATATGCAGCAGCTGCAGTTATCACATTCATGAATGCATGGAACTCATACCTGT
GGCCAAAGGTAATCCTCAATAAGCCTGATGCTATCACAATGCCAATGCTTATTGCAAACCTCGCAGCAGGATATACAGTA
GATTACGGTGTACTGATGATGGGCGTTCTTTTCTGCTCCATCCCTACAATGCTCGTATTCTTTGTGCTCCAGAAGCAGTT
TGCAGAGGGAATTACAGGATCTGTTAAATAA

Upstream 100 bases:

>100_bases
GAAGGCGTTGCAAACTTTGGATATGCATCAGCAATGTCTGTTATCGTATTCATCATGGTTGCTATACTGGCATTTATCAA
TCTGAAAGTAGGTGACAAGC

Downstream 100 bases:

>100_bases
AAGTAAAATAATATTGTTAAAAATCAAGAAGGCAAATAATATTTATTATTTGCCTTCGTCTTATAAGAGGCTTTGTGTTT
AAAACAGACATGTATCAAAT

Product: lactose transport system (permease)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTKKKHGSSIQKRLIPSYIFLVIVSFISVFPFFWMISAATNKSIDIARGRIAFGGYALENLKKLFASQNVALGMKNSLIN
ATVQTIIALLVCSLAGYGFELYHDKAKDKLFSVLLLAMMIPQVATLIPLFKMMSKLGFINTVWGFMLPAISTPFLIMMFR
QNSRNFPVDIMEAARIDGLSEIGIFFKMYMPVQKSTYAAAAVITFMNAWNSYLWPKVILNKPDAITMPMLIANLAAGYTV
DYGVLMMGVLFCSIPTMLVFFVLQKQFAEGITGSVK

Sequences:

>Translated_276_residues
MTKKKHGSSIQKRLIPSYIFLVIVSFISVFPFFWMISAATNKSIDIARGRIAFGGYALENLKKLFASQNVALGMKNSLIN
ATVQTIIALLVCSLAGYGFELYHDKAKDKLFSVLLLAMMIPQVATLIPLFKMMSKLGFINTVWGFMLPAISTPFLIMMFR
QNSRNFPVDIMEAARIDGLSEIGIFFKMYMPVQKSTYAAAAVITFMNAWNSYLWPKVILNKPDAITMPMLIANLAAGYTV
DYGVLMMGVLFCSIPTMLVFFVLQKQFAEGITGSVK
>Mature_275_residues
TKKKHGSSIQKRLIPSYIFLVIVSFISVFPFFWMISAATNKSIDIARGRIAFGGYALENLKKLFASQNVALGMKNSLINA
TVQTIIALLVCSLAGYGFELYHDKAKDKLFSVLLLAMMIPQVATLIPLFKMMSKLGFINTVWGFMLPAISTPFLIMMFRQ
NSRNFPVDIMEAARIDGLSEIGIFFKMYMPVQKSTYAAAAVITFMNAWNSYLWPKVILNKPDAITMPMLIANLAAGYTVD
YGVLMMGVLFCSIPTMLVFFVLQKQFAEGITGSVK

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789860, Length=270, Percent_Identity=26.2962962962963, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787571, Length=186, Percent_Identity=24.7311827956989, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30777; Mature: 30645

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TKKKHGSSIQKRLIPSYIFLVIVSFISVFPFFWMISAATNKSIDIARGRIAFGGYALEN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHCCHHHHHH
LKKLFASQNVALGMKNSLINATVQTIIALLVCSLAGYGFELYHDKAKDKLFSVLLLAMMI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
PQVATLIPLFKMMSKLGFINTVWGFMLPAISTPFLIMMFRQNSRNFPVDIMEAARIDGLS
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCHH
EIGIFFKMYMPVQKSTYAAAAVITFMNAWNSYLWPKVILNKPDAITMPMLIANLAAGYTV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCH
DYGVLMMGVLFCSIPTMLVFFVLQKQFAEGITGSVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]