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The map label for this gene is yclK [H]

Identifier: 238923748

GI number: 238923748

Start: 1244683

End: 1245957

Strand: Direct

Name: yclK [H]

Synonym: EUBREC_1370

Alternate gene names: 238923748

Gene position: 1244683-1245957 (Clockwise)

Preceding gene: 238923747

Following gene: 238923749

Centisome position: 36.08

GC content: 41.18

Gene sequence:

>1275_bases
ATGAGAAAGAAGAAATATAATTCAGAGAACAGAAAACATTTTGTGTATTTTGCAATAATATATACATGTATATGTGTGAC
GGTTATGGCTTTTACCGTCTTTTTTCAGTACAGGGCGTATACAAAAAACTATAACGTCACAGTGGCTAAGCTATGTGCGC
TTATTCATGAAAAATATCCCGATGTATCAGATGGCAGCATAGCCGCGATTCTAAATGACAGCAGCTTCGATAGTGATTAT
ACAAATTTAAAAAGCGCAGAGACGCTCTTAAAAAAATACGGCATTGATATGGAAAAGGATTCCGCGGTTTTGTCAAATGA
AAAAGCGCTTAAAGGAGCGCTTTGGCTAGACATATTTCTTGTTGTGCTTTTTGCAGGGGGCTTTTGCCTTTACATTGTGC
TTATAAGATTTAGCTTTAAAAGACAGGTCAGACAGGCTGCGGATTATCTGCGCCGCATAAATCAGGGAGACTACAGACTT
TTTATGGCAGATAGCACAGAGGGAGAGATTTCTATACTAAAGGGAGAGCTTTACAAGACAGCAATCTATTTGAGGGAGTC
TGCGGAAAATGCAAAGGCAGACAAGCTTTTGCTAAAGGATGCGCTTTCTGACATATCGCATCAGCTTAAGACACCGCTCA
CATCACTTTCGATAAATCTGGAAAATCTGGAAGGAAATCCTGATATGGCACCTGAAAACAGAAGCAGGATAATGCGCAGG
GCAAAGCGTGATGTGGATAATATATCGCATATGGTGCAGGCTATCTTAAAGCTTTCAAGGCTTGAAGCGGATGTTGTGGA
GTTTGATGAGAAGGATACGCTGCTGTCTGAAATTGTGTCTGAGGCAGCTGACAATGTTATGGCACTTTGCGATTTGAGAG
ACATAAGGCTGTCCATAGATGAAGGCTCTGATAAGGATGCCTGTATACATGCTGATGCATACTGGCAGTGTGAGGCCATT
ACAAACATAGTAAAAAATGCAGTAGAGCACGCAGAGAGTGAGGTAAAGATAGGCTTTTACAGGTATGAGATGTATGCAGA
GATAACAGTGCAAAACGATGGAGAAGCCATAAGTGATGAGGACAAAAAGCATATTTTTACGCGTTTTTACAGCGGCAGCG
GACAGCCGGCAGACAGCATCGGCATAGGACTTTCGCTCGCGGAAGCAATTGTGCGTCATGACAATGGATATATCATTGTG
GAGGATTGTAAAAAAGATGTATTAAATGAAAAAAATGAATGCAGTGGCACACGCTTTGTGGTAAGATATTTGTGA

Upstream 100 bases:

>100_bases
AGAATGTGATAAAGACTGTGAAGGGAATCGGGTATCGTGTTGATTCAGATGAAGCTCTTTAAACAGTATCGGTCGACAGA
GACAGTTCCCGGGGGAAAGC

Downstream 100 bases:

>100_bases
TAAGTTGAGAAAAATTATCAATAAATACACTAGGAAGCGATAAAATGACACTAAAAGAACTTGGCATAGGACAGAGTGCC
AGAATACTTACAGTAGGCGG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRKKKYNSENRKHFVYFAIIYTCICVTVMAFTVFFQYRAYTKNYNVTVAKLCALIHEKYPDVSDGSIAAILNDSSFDSDY
TNLKSAETLLKKYGIDMEKDSAVLSNEKALKGALWLDIFLVVLFAGGFCLYIVLIRFSFKRQVRQAADYLRRINQGDYRL
FMADSTEGEISILKGELYKTAIYLRESAENAKADKLLLKDALSDISHQLKTPLTSLSINLENLEGNPDMAPENRSRIMRR
AKRDVDNISHMVQAILKLSRLEADVVEFDEKDTLLSEIVSEAADNVMALCDLRDIRLSIDEGSDKDACIHADAYWQCEAI
TNIVKNAVEHAESEVKIGFYRYEMYAEITVQNDGEAISDEDKKHIFTRFYSGSGQPADSIGIGLSLAEAIVRHDNGYIIV
EDCKKDVLNEKNECSGTRFVVRYL

Sequences:

>Translated_424_residues
MRKKKYNSENRKHFVYFAIIYTCICVTVMAFTVFFQYRAYTKNYNVTVAKLCALIHEKYPDVSDGSIAAILNDSSFDSDY
TNLKSAETLLKKYGIDMEKDSAVLSNEKALKGALWLDIFLVVLFAGGFCLYIVLIRFSFKRQVRQAADYLRRINQGDYRL
FMADSTEGEISILKGELYKTAIYLRESAENAKADKLLLKDALSDISHQLKTPLTSLSINLENLEGNPDMAPENRSRIMRR
AKRDVDNISHMVQAILKLSRLEADVVEFDEKDTLLSEIVSEAADNVMALCDLRDIRLSIDEGSDKDACIHADAYWQCEAI
TNIVKNAVEHAESEVKIGFYRYEMYAEITVQNDGEAISDEDKKHIFTRFYSGSGQPADSIGIGLSLAEAIVRHDNGYIIV
EDCKKDVLNEKNECSGTRFVVRYL
>Mature_424_residues
MRKKKYNSENRKHFVYFAIIYTCICVTVMAFTVFFQYRAYTKNYNVTVAKLCALIHEKYPDVSDGSIAAILNDSSFDSDY
TNLKSAETLLKKYGIDMEKDSAVLSNEKALKGALWLDIFLVVLFAGGFCLYIVLIRFSFKRQVRQAADYLRRINQGDYRL
FMADSTEGEISILKGELYKTAIYLRESAENAKADKLLLKDALSDISHQLKTPLTSLSINLENLEGNPDMAPENRSRIMRR
AKRDVDNISHMVQAILKLSRLEADVVEFDEKDTLLSEIVSEAADNVMALCDLRDIRLSIDEGSDKDACIHADAYWQCEAI
TNIVKNAVEHAESEVKIGFYRYEMYAEITVQNDGEAISDEDKKHIFTRFYSGSGQPADSIGIGLSLAEAIVRHDNGYIIV
EDCKKDVLNEKNECSGTRFVVRYL

Specific function: Could be member of the two-component regulatory system yclK/yclJ. Potentially phosphorylates yclJ [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=209, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48137; Mature: 48137

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKKYNSENRKHFVYFAIIYTCICVTVMAFTVFFQYRAYTKNYNVTVAKLCALIHEKYP
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
DVSDGSIAAILNDSSFDSDYTNLKSAETLLKKYGIDMEKDSAVLSNEKALKGALWLDIFL
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHH
VVLFAGGFCLYIVLIRFSFKRQVRQAADYLRRINQGDYRLFMADSTEGEISILKGELYKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEHHHHHHH
AIYLRESAENAKADKLLLKDALSDISHQLKTPLTSLSINLENLEGNPDMAPENRSRIMRR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCHHHHHHHH
AKRDVDNISHMVQAILKLSRLEADVVEFDEKDTLLSEIVSEAADNVMALCDLRDIRLSID
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEHCCCEEEEEEEC
EGSDKDACIHADAYWQCEAITNIVKNAVEHAESEVKIGFYRYEMYAEITVQNDGEAISDE
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEECCCCCCCCC
DKKHIFTRFYSGSGQPADSIGIGLSLAEAIVRHDNGYIIVEDCKKDVLNEKNECSGTRFV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCCCCCCEEE
VRYL
EEEC
>Mature Secondary Structure
MRKKKYNSENRKHFVYFAIIYTCICVTVMAFTVFFQYRAYTKNYNVTVAKLCALIHEKYP
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
DVSDGSIAAILNDSSFDSDYTNLKSAETLLKKYGIDMEKDSAVLSNEKALKGALWLDIFL
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHH
VVLFAGGFCLYIVLIRFSFKRQVRQAADYLRRINQGDYRLFMADSTEGEISILKGELYKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEHHHHHHH
AIYLRESAENAKADKLLLKDALSDISHQLKTPLTSLSINLENLEGNPDMAPENRSRIMRR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCHHHHHHHH
AKRDVDNISHMVQAILKLSRLEADVVEFDEKDTLLSEIVSEAADNVMALCDLRDIRLSID
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEHCCCEEEEEEEC
EGSDKDACIHADAYWQCEAITNIVKNAVEHAESEVKIGFYRYEMYAEITVQNDGEAISDE
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEECCCCCCCCC
DKKHIFTRFYSGSGQPADSIGIGLSLAEAIVRHDNGYIIVEDCKKDVLNEKNECSGTRFV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCCCCCCEEE
VRYL
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]