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The map label for this gene is xerC [H]

Identifier: 238923684

GI number: 238923684

Start: 1185081

End: 1186076

Strand: Direct

Name: xerC [H]

Synonym: EUBREC_1306

Alternate gene names: 238923684

Gene position: 1185081-1186076 (Clockwise)

Preceding gene: 238923683

Following gene: 238923686

Centisome position: 34.35

GC content: 37.45

Gene sequence:

>996_bases
ATGCGTGAACATTTTGTAAATGAATTCATGGCCGTATTATCAAACAAATTAACGGAAGATGCGTTGAGCATCGTGTATCA
AAGTCTGACTCTGTTTGTAAGTAATTATGAGATAAGCGAGCGTAATACAGAGGTGGTACCATATACAGGATATCTACCTG
AATGCTACGAGACATATTTTGTCACAAGAAAAATTGAGGGAATGAGCATGAAGTCATTAGAGCTATATAATTTGGTCCTG
AAAGATTTTTTCTTTAAGCTCAATAAAGAGATATGCAAAATTTCCACAAATGATATTCGCGTTTACTTGTATAAAAACCA
GCAGGAGAGAAATCTGTCAAATTCCACATTAGACACGAAAAGAACTATCATACATGCATTTTTTGAATGGGCTGCGAATG
AGGGATACATAGGTAGTAATCCGTGCAGGAACATCAAACCAATAAAGTATGAACGTCCTAAAAGAAAGCCACTTACAGGA
ATAGAACTTGAAAAGGTGAGAAATGCATGTGACAATTTGAAAGACAAGGCACTTTTGGAGCTATTCTACAGCACAGGATG
CAGAGTCACAGAGATGGAGAGACTTGATATATCTGATATAGATTTTCAGACAAAAGAGGTTTTACTGTTTGGAAAAGGAG
ACAAGCACAGAATATCATACCTGAATGCTAAGGCTGAAATTGCCATCAGAAACTATCTTGATTCGAGAAATGATAACGAA
GAGGCATTATTTGTATCGGACAGGAAACCATATGGCAGGTTGAAAAAACCGGCTATAGAGAAGCGTATCAGAGTGCTAGG
TGAAAAATCTGGAATAGGAAGGCGCCTATATCCGCATCTGATCAGGCACACAACGGCAACTGATGGACTAGATAGAGGAA
TGCCTGTTGAAGAGGTACAACAGATTTTAGGACATGTAAACATTGCAACAACTATGATATATGCAGAGGTATCAAGAGCA
AACGTGAAAAACAATCACAGAAAATGTATTGTTTAA

Upstream 100 bases:

>100_bases
CCGTCTACCAAACAAAAAGCTCGACTCCTGCACCACAAAGGGTTCGGGCATATTATAGCATAGTTCCCTCCCTTTGTGTA
CCACAAAAGGAGGATTTTTT

Downstream 100 bases:

>100_bases
TGTAGAAAAATGATAACATAGTAGAGAAATTATATTAAATTTGTGTTATAATTAAAAATAACAAAACAGATGAAGAAAGA
TACATTAGAGCCTGAGAGCC

Product: site-specific tyrosine recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MREHFVNEFMAVLSNKLTEDALSIVYQSLTLFVSNYEISERNTEVVPYTGYLPECYETYFVTRKIEGMSMKSLELYNLVL
KDFFFKLNKEICKISTNDIRVYLYKNQQERNLSNSTLDTKRTIIHAFFEWAANEGYIGSNPCRNIKPIKYERPKRKPLTG
IELEKVRNACDNLKDKALLELFYSTGCRVTEMERLDISDIDFQTKEVLLFGKGDKHRISYLNAKAEIAIRNYLDSRNDNE
EALFVSDRKPYGRLKKPAIEKRIRVLGEKSGIGRRLYPHLIRHTTATDGLDRGMPVEEVQQILGHVNIATTMIYAEVSRA
NVKNNHRKCIV

Sequences:

>Translated_331_residues
MREHFVNEFMAVLSNKLTEDALSIVYQSLTLFVSNYEISERNTEVVPYTGYLPECYETYFVTRKIEGMSMKSLELYNLVL
KDFFFKLNKEICKISTNDIRVYLYKNQQERNLSNSTLDTKRTIIHAFFEWAANEGYIGSNPCRNIKPIKYERPKRKPLTG
IELEKVRNACDNLKDKALLELFYSTGCRVTEMERLDISDIDFQTKEVLLFGKGDKHRISYLNAKAEIAIRNYLDSRNDNE
EALFVSDRKPYGRLKKPAIEKRIRVLGEKSGIGRRLYPHLIRHTTATDGLDRGMPVEEVQQILGHVNIATTMIYAEVSRA
NVKNNHRKCIV
>Mature_331_residues
MREHFVNEFMAVLSNKLTEDALSIVYQSLTLFVSNYEISERNTEVVPYTGYLPECYETYFVTRKIEGMSMKSLELYNLVL
KDFFFKLNKEICKISTNDIRVYLYKNQQERNLSNSTLDTKRTIIHAFFEWAANEGYIGSNPCRNIKPIKYERPKRKPLTG
IELEKVRNACDNLKDKALLELFYSTGCRVTEMERLDISDIDFQTKEVLLFGKGDKHRISYLNAKAEIAIRNYLDSRNDNE
EALFVSDRKPYGRLKKPAIEKRIRVLGEKSGIGRRLYPHLIRHTTATDGLDRGMPVEEVQQILGHVNIATTMIYAEVSRA
NVKNNHRKCIV

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=220, Percent_Identity=29.0909090909091, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789261, Length=216, Percent_Identity=30.0925925925926, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38504; Mature: 38504

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREHFVNEFMAVLSNKLTEDALSIVYQSLTLFVSNYEISERNTEVVPYTGYLPECYETYF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCHHHHHHHH
VTRKIEGMSMKSLELYNLVLKDFFFKLNKEICKISTNDIRVYLYKNQQERNLSNSTLDTK
HHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCHHCCCCCCCHHHH
RTIIHAFFEWAANEGYIGSNPCRNIKPIKYERPKRKPLTGIELEKVRNACDNLKDKALLE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHH
LFYSTGCRVTEMERLDISDIDFQTKEVLLFGKGDKHRISYLNAKAEIAIRNYLDSRNDNE
HHHHCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCCCC
EALFVSDRKPYGRLKKPAIEKRIRVLGEKSGIGRRLYPHLIRHTTATDGLDRGMPVEEVQ
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHH
QILGHVNIATTMIYAEVSRANVKNNHRKCIV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MREHFVNEFMAVLSNKLTEDALSIVYQSLTLFVSNYEISERNTEVVPYTGYLPECYETYF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCHHHHHHHH
VTRKIEGMSMKSLELYNLVLKDFFFKLNKEICKISTNDIRVYLYKNQQERNLSNSTLDTK
HHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCHHCCCCCCCHHHH
RTIIHAFFEWAANEGYIGSNPCRNIKPIKYERPKRKPLTGIELEKVRNACDNLKDKALLE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHH
LFYSTGCRVTEMERLDISDIDFQTKEVLLFGKGDKHRISYLNAKAEIAIRNYLDSRNDNE
HHHHCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCCCC
EALFVSDRKPYGRLKKPAIEKRIRVLGEKSGIGRRLYPHLIRHTTATDGLDRGMPVEEVQ
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHH
QILGHVNIATTMIYAEVSRANVKNNHRKCIV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA