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The map label for this gene is ctpC [H]

Identifier: 238923612

GI number: 238923612

Start: 1131790

End: 1133871

Strand: Direct

Name: ctpC [H]

Synonym: EUBREC_1234

Alternate gene names: 238923612

Gene position: 1131790-1133871 (Clockwise)

Preceding gene: 238923611

Following gene: 238923613

Centisome position: 32.81

GC content: 45.34

Gene sequence:

>2082_bases
ATGAAATTTACGATTAAGCATGAGTCAAGAGGCCGTATGCGTGTTCATATGGAGCAGTACCGCATGACATATGAGCAGGC
GGACACTCTGCTTTATGTGATTCACAATCACAGGAATGTTACCTTTGTAAAGGTTTATGACAGGACGGCTGATGCTGTGA
TTGAGTATGTAGGAGACAGAGAGCAGATTATAGAGCTGCTTCGCCACTTTCATTATGAGAGCGCCAATGTGCCACAGACT
GTTATTAAGACATCAGGAAGAGAGCTTAATAATTCATATCAGGAAAAACTTATCGGAAGTGTTGTCTGGCATTACAGTAA
AAAGCTCCTGCTGCCTTTGCCAATCAGGATAGCGCTTACTATTGGACGATCTGTAAAGTATATTGGAATTGGGCTTAAGT
GTCTGCTGCAGAGAAAAATTGAAGTGCCGGTGCTTGATGCTACTGCCATCACGGTTTCGCTTGTCACAAAGGATTTTTCT
ACCGCAAGCTCTATTATGTTTCTGCTTGGAATAGGTGAGCTTTTGGAGGAATGGACACACAAGAAGTCTGTTGATGACCT
GGCCAGAAGCATGTCGCTTAATGTGAGCAAGGTATGGCTTAGGACACCTGAGAATCAGGAGATACTCGTTGAGTCCTCAA
AGATTGAAAAGGGCGACAAGGTTGTTGTCCACATGGGAAATGTCATACCGTTCGACGGAGAGGTATTAGATGGCGATGCG
ATGGTCAATCAGGCTTCCCTGACAGGTGAGTCGGTTCCGGTTCAAAGAACTGTCGGCAATACTGTGTTTGCAGGCACTGT
TGTCGAGGAGGGCGAGATTACTATCAGGGTCAAGGAGGTTGAAGGAAACAACCGTTTTGACCAGATTGTTACTATGATAG
AGGAGTCCGAAAAGCTTAAATCTGAGCTGGAGGGAAAGGCTGAGCACTATGCTGACAAGCTTGTGCCGTGGACGCTTGGA
GCTACAGGGCTTACATATCTTCTGACAAGAAATGTGACAAAGGCTATGTCAATTCTCATGGTGGATTTCTGCTGTGCACT
CAAGCTTGCTATGCCAATCTCTGTGCTTTCTGCTATCAGAGAGGCAAGCCTTTATAATGTAACAGTAAAGGGAGGAAAGT
TCCTTGAGGCTGTTGCGGAGGCTGATACCATCGTCTTTGACAAGACCGGTACACTCACAAAGGCACATCCGACTGTGGTT
GATGTGGTGAACTTCAATGATGAGTATTCATCTGATGACATGCTTCGTGTTGCAGCCTGTCTGGAGGAGCATTTCCCTCA
TTCAATGGCAAAGGCAGTGGTAGACGCTGCGTCTAAGAAGGGGCTTTCCCACGAGGAAATGCATACAAAGGTGGAGTATA
TTGTGGCTCATGGAATTGCAACCTCCATCAATGGCAAGCGTACTGTTATCGGAAGCTATCATTTTGTCTTTGAGGATGAA
AAATGTGTTGTTCCTGCAGGAAAGGAGCCACTGTTTGAGTCGCTTCCGCTGTATTATTCTCACCTGTATCTGGCTATTGA
GGGTAAGCTTTCGGCAGTTATCTGTATAGAGGATCCTCTGCGTGATGAGGCAGCAGCAGTTGTTACTTCATTAAAGAAGG
CAGGCATATCAAAGGTTGTCATGATGACAGGAGACAGTGAGCGTACAGCTTCTGTCATTGCGAAAAAAGTAGGTGTAGAT
GAATACTACGCCGAGGTTTTACCTGAGGACAAGGCTGCCTTTGTGGAGAGAGAAAAGGATAAGGGCAGAAAGGTCATTAT
GATTGGTGACGGCATAAATGATTCACCGGCTCTTTCTGCGGCAAATGTCGGTATTGCAATCAGTGACGGCGCTGAAATTG
CCCGCGAGATTGCTGATATTACGGTGGGCTCGGATGATCTCTACCAGATTGTAACTCTTAAATATATAAGTAATGCTCTT
ATGAAACGTATAAAGAGCAACTATCGAAAGATTGTTGGTTTTAACTCAGGGCTCATTGCTCTTGGTGTGGCAGGTGTGCT
TCCGCCGACTACGACAGCACTTTTGCACAATGGATCGACAATTCTTATCAGTGTGAACAGTATGAAGAATCTGCTTGAGT
AG

Upstream 100 bases:

>100_bases
TGAGGATGTATGCGAGTGTGCTAAGGCTGATGAGCAGGAAGCAGAGCAGGCTGAGGTTACAGCAGAGACTGCTGAGGCAT
AGAAGATAAGAGGCGGTCAT

Downstream 100 bases:

>100_bases
ATTTTGGATGTCAATGTTTATTGATGTAGTACGGGGCGCTGCCGCGGGTACCGTGGTGGCACACGTACTATCCCGCGTGC
TACGCTTCGTGGGTAAGATA

Product: hypothetical protein

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MKFTIKHESRGRMRVHMEQYRMTYEQADTLLYVIHNHRNVTFVKVYDRTADAVIEYVGDREQIIELLRHFHYESANVPQT
VIKTSGRELNNSYQEKLIGSVVWHYSKKLLLPLPIRIALTIGRSVKYIGIGLKCLLQRKIEVPVLDATAITVSLVTKDFS
TASSIMFLLGIGELLEEWTHKKSVDDLARSMSLNVSKVWLRTPENQEILVESSKIEKGDKVVVHMGNVIPFDGEVLDGDA
MVNQASLTGESVPVQRTVGNTVFAGTVVEEGEITIRVKEVEGNNRFDQIVTMIEESEKLKSELEGKAEHYADKLVPWTLG
ATGLTYLLTRNVTKAMSILMVDFCCALKLAMPISVLSAIREASLYNVTVKGGKFLEAVAEADTIVFDKTGTLTKAHPTVV
DVVNFNDEYSSDDMLRVAACLEEHFPHSMAKAVVDAASKKGLSHEEMHTKVEYIVAHGIATSINGKRTVIGSYHFVFEDE
KCVVPAGKEPLFESLPLYYSHLYLAIEGKLSAVICIEDPLRDEAAAVVTSLKKAGISKVVMMTGDSERTASVIAKKVGVD
EYYAEVLPEDKAAFVEREKDKGRKVIMIGDGINDSPALSAANVGIAISDGAEIAREIADITVGSDDLYQIVTLKYISNAL
MKRIKSNYRKIVGFNSGLIALGVAGVLPPTTTALLHNGSTILISVNSMKNLLE

Sequences:

>Translated_693_residues
MKFTIKHESRGRMRVHMEQYRMTYEQADTLLYVIHNHRNVTFVKVYDRTADAVIEYVGDREQIIELLRHFHYESANVPQT
VIKTSGRELNNSYQEKLIGSVVWHYSKKLLLPLPIRIALTIGRSVKYIGIGLKCLLQRKIEVPVLDATAITVSLVTKDFS
TASSIMFLLGIGELLEEWTHKKSVDDLARSMSLNVSKVWLRTPENQEILVESSKIEKGDKVVVHMGNVIPFDGEVLDGDA
MVNQASLTGESVPVQRTVGNTVFAGTVVEEGEITIRVKEVEGNNRFDQIVTMIEESEKLKSELEGKAEHYADKLVPWTLG
ATGLTYLLTRNVTKAMSILMVDFCCALKLAMPISVLSAIREASLYNVTVKGGKFLEAVAEADTIVFDKTGTLTKAHPTVV
DVVNFNDEYSSDDMLRVAACLEEHFPHSMAKAVVDAASKKGLSHEEMHTKVEYIVAHGIATSINGKRTVIGSYHFVFEDE
KCVVPAGKEPLFESLPLYYSHLYLAIEGKLSAVICIEDPLRDEAAAVVTSLKKAGISKVVMMTGDSERTASVIAKKVGVD
EYYAEVLPEDKAAFVEREKDKGRKVIMIGDGINDSPALSAANVGIAISDGAEIAREIADITVGSDDLYQIVTLKYISNAL
MKRIKSNYRKIVGFNSGLIALGVAGVLPPTTTALLHNGSTILISVNSMKNLLE
>Mature_693_residues
MKFTIKHESRGRMRVHMEQYRMTYEQADTLLYVIHNHRNVTFVKVYDRTADAVIEYVGDREQIIELLRHFHYESANVPQT
VIKTSGRELNNSYQEKLIGSVVWHYSKKLLLPLPIRIALTIGRSVKYIGIGLKCLLQRKIEVPVLDATAITVSLVTKDFS
TASSIMFLLGIGELLEEWTHKKSVDDLARSMSLNVSKVWLRTPENQEILVESSKIEKGDKVVVHMGNVIPFDGEVLDGDA
MVNQASLTGESVPVQRTVGNTVFAGTVVEEGEITIRVKEVEGNNRFDQIVTMIEESEKLKSELEGKAEHYADKLVPWTLG
ATGLTYLLTRNVTKAMSILMVDFCCALKLAMPISVLSAIREASLYNVTVKGGKFLEAVAEADTIVFDKTGTLTKAHPTVV
DVVNFNDEYSSDDMLRVAACLEEHFPHSMAKAVVDAASKKGLSHEEMHTKVEYIVAHGIATSINGKRTVIGSYHFVFEDE
KCVVPAGKEPLFESLPLYYSHLYLAIEGKLSAVICIEDPLRDEAAAVVTSLKKAGISKVVMMTGDSERTASVIAKKVGVD
EYYAEVLPEDKAAFVEREKDKGRKVIMIGDGINDSPALSAANVGIAISDGAEIAREIADITVGSDDLYQIVTLKYISNAL
MKRIKSNYRKIVGFNSGLIALGVAGVLPPTTTALLHNGSTILISVNSMKNLLE

Specific function: Involved In Copper Efflux. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=586, Percent_Identity=26.962457337884, Blast_Score=219, Evalue=6e-57,
Organism=Homo sapiens, GI115529486, Length=602, Percent_Identity=26.578073089701, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI55743073, Length=533, Percent_Identity=28.1425891181989, Blast_Score=202, Evalue=9e-52,
Organism=Escherichia coli, GI1786691, Length=536, Percent_Identity=31.3432835820896, Blast_Score=236, Evalue=5e-63,
Organism=Escherichia coli, GI1789879, Length=556, Percent_Identity=29.3165467625899, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1786914, Length=444, Percent_Identity=29.0540540540541, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI2367363, Length=136, Percent_Identity=33.8235294117647, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556548, Length=597, Percent_Identity=28.4757118927973, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17554158, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71988506, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193210130, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319772, Length=552, Percent_Identity=25.9057971014493, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6320475, Length=548, Percent_Identity=28.8321167883212, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6321430, Length=588, Percent_Identity=23.6394557823129, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321271, Length=203, Percent_Identity=27.0935960591133, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321432, Length=156, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221329854, Length=177, Percent_Identity=37.8531073446328, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24762455, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762453, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762447, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762457, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762449, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762445, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762451, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136664, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 76416; Mature: 76416

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTIKHESRGRMRVHMEQYRMTYEQADTLLYVIHNHRNVTFVKVYDRTADAVIEYVGDR
CEEEEEECCCCCEEEEHHHHHHHHHHCCEEEEEEECCCCEEEEEEECCCHHHHHHHHCCH
EQIIELLRHFHYESANVPQTVIKTSGRELNNSYQEKLIGSVVWHYSKKLLLPLPIRIALT
HHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEE
IGRSVKYIGIGLKCLLQRKIEVPVLDATAITVSLVTKDFSTASSIMFLLGIGELLEEWTH
ECCCEEEEEHHHHHHHHHCCCCCEEEHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KKSVDDLARSMSLNVSKVWLRTPENQEILVESSKIEKGDKVVVHMGNVIPFDGEVLDGDA
CCCHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCEECCHH
MVNQASLTGESVPVQRTVGNTVFAGTVVEEGEITIRVKEVEGNNRFDQIVTMIEESEKLK
HEEHHHCCCCCCCCHHHCCCEEEEEEEEECCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
SELEGKAEHYADKLVPWTLGATGLTYLLTRNVTKAMSILMVDFCCALKLAMPISVLSAIR
HHHCCHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EASLYNVTVKGGKFLEAVAEADTIVFDKTGTLTKAHPTVVDVVNFNDEYSSDDMLRVAAC
HCCEEEEEECCCHHHHHHHCCCEEEEECCCCCEECCCCEEEEEECCCCCCCCHHHHHHHH
LEEHFPHSMAKAVVDAASKKGLSHEEMHTKVEYIVAHGIATSINGKRTVIGSYHFVFEDE
HHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCEEEEEEEEEEEECC
KCVVPAGKEPLFESLPLYYSHLYLAIEGKLSAVICIEDPLRDEAAAVVTSLKKAGISKVV
EEEECCCCCCHHHHCCHHEEEEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEE
MMTGDSERTASVIAKKVGVDEYYAEVLPEDKAAFVEREKDKGRKVIMIGDGINDSPALSA
EEECCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCEE
ANVGIAISDGAEIAREIADITVGSDDLYQIVTLKYISNALMKRIKSNYRKIVGFNSGLIA
CCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
LGVAGVLPPTTTALLHNGSTILISVNSMKNLLE
HHHHCCCCCCCCEEEECCCEEEEEEHHHHHHCC
>Mature Secondary Structure
MKFTIKHESRGRMRVHMEQYRMTYEQADTLLYVIHNHRNVTFVKVYDRTADAVIEYVGDR
CEEEEEECCCCCEEEEHHHHHHHHHHCCEEEEEEECCCCEEEEEEECCCHHHHHHHHCCH
EQIIELLRHFHYESANVPQTVIKTSGRELNNSYQEKLIGSVVWHYSKKLLLPLPIRIALT
HHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEE
IGRSVKYIGIGLKCLLQRKIEVPVLDATAITVSLVTKDFSTASSIMFLLGIGELLEEWTH
ECCCEEEEEHHHHHHHHHCCCCCEEEHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KKSVDDLARSMSLNVSKVWLRTPENQEILVESSKIEKGDKVVVHMGNVIPFDGEVLDGDA
CCCHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCEECCHH
MVNQASLTGESVPVQRTVGNTVFAGTVVEEGEITIRVKEVEGNNRFDQIVTMIEESEKLK
HEEHHHCCCCCCCCHHHCCCEEEEEEEEECCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
SELEGKAEHYADKLVPWTLGATGLTYLLTRNVTKAMSILMVDFCCALKLAMPISVLSAIR
HHHCCHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EASLYNVTVKGGKFLEAVAEADTIVFDKTGTLTKAHPTVVDVVNFNDEYSSDDMLRVAAC
HCCEEEEEECCCHHHHHHHCCCEEEEECCCCCEECCCCEEEEEECCCCCCCCHHHHHHHH
LEEHFPHSMAKAVVDAASKKGLSHEEMHTKVEYIVAHGIATSINGKRTVIGSYHFVFEDE
HHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCEEEEEEEEEEEECC
KCVVPAGKEPLFESLPLYYSHLYLAIEGKLSAVICIEDPLRDEAAAVVTSLKKAGISKVV
EEEECCCCCCHHHHCCHHEEEEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEE
MMTGDSERTASVIAKKVGVDEYYAEVLPEDKAAFVEREKDKGRKVIMIGDGINDSPALSA
EEECCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCEE
ANVGIAISDGAEIAREIADITVGSDDLYQIVTLKYISNALMKRIKSNYRKIVGFNSGLIA
CCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
LGVAGVLPPTTTALLHNGSTILISVNSMKNLLE
HHHHCCCCCCCCEEEECCCEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]