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The map label for this gene is adhB [H]

Identifier: 238923581

GI number: 238923581

Start: 1109466

End: 1110620

Strand: Direct

Name: adhB [H]

Synonym: EUBREC_1203

Alternate gene names: 238923581

Gene position: 1109466-1110620 (Clockwise)

Preceding gene: 238923580

Following gene: 238923582

Centisome position: 32.16

GC content: 40.78

Gene sequence:

>1155_bases
ATGAGTTATCAGATTAAAATTCCGTCATGTATCTTTGGCGGAGCAGGAAGCATTGAGAATGTGAAAGCGGTAATAGAAAA
AGAGAATGCAAAAAAAGTAATAATTTTTACTGATAAAGGCATTCGCTCAACAGGACTTTTAGATCTGCTGACAGACATTC
TTGAGGAAAACAAGACAGAGTATCAGGTATTTGATGATCTTGCTTGTGAACCATCATATCAGGATGTTGAAAAGGTTATG
AAGGAAGTGGAGAACACATCAGGTGATCTTATCATAGCAATCGGTGGGGGAAGCGTTATGGATGCAGCAAAGCTTTGCTG
CGTATTAAAAGATGCAGACTATACTATAAAAGATTTGCTCAATGATCCGATGCTTGCAAAGAAACAGATTAAGACGGTTA
TGATTCCGACAACATGCGGAACAGGATCTGAGGCAACCTGCAATGCAATCGTTGCGGTTCCGGAGGAACAGTCAAAGAAA
GGAATTGTAAATGACAGTATGATTCCGGACTATGTGGTATTGGATTCGAATATGATCAGAAAGCTTCCAAAATCAATTGT
GGCAGCAACAGGTGTAGATGCATTGGCCCATGTGGTTGAGTGCTTCACCTCAAAGAAAGCAACACCGTTTTCCGATACCT
ATGCAGCAGCCGGAGCCAAGCTTATTTTCCATAATATCAGGGAAGCTTATAACAATCCGGACAATATGGAAGCAAAAAGC
AATATGATGACCGGAGCCTTCTATGGCGGAGTCGCAATTACAGGAAGCGGAACAACAGCAGTTCATGCGCTTTCATATCC
ACTGGGAGGCAAATATCACATTGCTCACGGTGTATCAAATGCCATACTTTTTGCACATGTTATGGAATTTAACAAGGACG
CATGCAGCAAGAGACTTGCAATACTTTGCGATGCTGTTTACCCTGAGCTTGCAGGAAAATCTGAGGATGAGAAAGCACAG
TACATGATCGATCAGATTGCTGACATTGTAAAGGTTACAAACATTCCAACAGATTTAAAGGAATTCGGTGTTAAGCCGGA
GGACCTGGATTTCCTTGTTGATGCCGGAAGCAAACAGCAGAGACTTCTTGTAAACAATATGAAAGAATTAAGTCTTGACG
ATATCAGAAACATATATCTTAAGGTGTTAAAATAA

Upstream 100 bases:

>100_bases
CGTTGAACGTGGCTCAAAAAACAGATATTATATGATTAGTTCAAAGAGATGTTCAAAAATAAAACACAAGAATAACAATA
TAACAAAGGAGAGGTAATAT

Downstream 100 bases:

>100_bases
AGGAGGACCTATGAAAAAGCCAATTATCGGAATTACAATGGGAGATCCTGCAGGAAACGGTTCTGAGATTTCAGTAAAAG
CGTTATCAAGATCGGAAATA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSYQIKIPSCIFGGAGSIENVKAVIEKENAKKVIIFTDKGIRSTGLLDLLTDILEENKTEYQVFDDLACEPSYQDVEKVM
KEVENTSGDLIIAIGGGSVMDAAKLCCVLKDADYTIKDLLNDPMLAKKQIKTVMIPTTCGTGSEATCNAIVAVPEEQSKK
GIVNDSMIPDYVVLDSNMIRKLPKSIVAATGVDALAHVVECFTSKKATPFSDTYAAAGAKLIFHNIREAYNNPDNMEAKS
NMMTGAFYGGVAITGSGTTAVHALSYPLGGKYHIAHGVSNAILFAHVMEFNKDACSKRLAILCDAVYPELAGKSEDEKAQ
YMIDQIADIVKVTNIPTDLKEFGVKPEDLDFLVDAGSKQQRLLVNNMKELSLDDIRNIYLKVLK

Sequences:

>Translated_384_residues
MSYQIKIPSCIFGGAGSIENVKAVIEKENAKKVIIFTDKGIRSTGLLDLLTDILEENKTEYQVFDDLACEPSYQDVEKVM
KEVENTSGDLIIAIGGGSVMDAAKLCCVLKDADYTIKDLLNDPMLAKKQIKTVMIPTTCGTGSEATCNAIVAVPEEQSKK
GIVNDSMIPDYVVLDSNMIRKLPKSIVAATGVDALAHVVECFTSKKATPFSDTYAAAGAKLIFHNIREAYNNPDNMEAKS
NMMTGAFYGGVAITGSGTTAVHALSYPLGGKYHIAHGVSNAILFAHVMEFNKDACSKRLAILCDAVYPELAGKSEDEKAQ
YMIDQIADIVKVTNIPTDLKEFGVKPEDLDFLVDAGSKQQRLLVNNMKELSLDDIRNIYLKVLK
>Mature_383_residues
SYQIKIPSCIFGGAGSIENVKAVIEKENAKKVIIFTDKGIRSTGLLDLLTDILEENKTEYQVFDDLACEPSYQDVEKVMK
EVENTSGDLIIAIGGGSVMDAAKLCCVLKDADYTIKDLLNDPMLAKKQIKTVMIPTTCGTGSEATCNAIVAVPEEQSKKG
IVNDSMIPDYVVLDSNMIRKLPKSIVAATGVDALAHVVECFTSKKATPFSDTYAAAGAKLIFHNIREAYNNPDNMEAKSN
MMTGAFYGGVAITGSGTTAVHALSYPLGGKYHIAHGVSNAILFAHVMEFNKDACSKRLAILCDAVYPELAGKSEDEKAQY
MIDQIADIVKVTNIPTDLKEFGVKPEDLDFLVDAGSKQQRLLVNNMKELSLDDIRNIYLKVLK

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=287, Percent_Identity=25.7839721254355, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI48994951, Length=346, Percent_Identity=31.5028901734104, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI87082107, Length=376, Percent_Identity=26.8617021276596, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789163, Length=383, Percent_Identity=26.3707571801567, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1787493, Length=408, Percent_Identity=26.2254901960784, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789386, Length=387, Percent_Identity=23.5142118863049, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17537053, Length=395, Percent_Identity=26.5822784810127, Blast_Score=144, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6321181, Length=350, Percent_Identity=31.7142857142857, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24657991, Length=423, Percent_Identity=26.241134751773, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41728; Mature: 41596

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQIKIPSCIFGGAGSIENVKAVIEKENAKKVIIFTDKGIRSTGLLDLLTDILEENKTE
CCEEEECCCEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCH
YQVFDDLACEPSYQDVEKVMKEVENTSGDLIIAIGGGSVMDAAKLCCVLKDADYTIKDLL
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHC
NDPMLAKKQIKTVMIPTTCGTGSEATCNAIVAVPEEQSKKGIVNDSMIPDYVVLDSNMIR
CCCHHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCHHHH
KLPKSIVAATGVDALAHVVECFTSKKATPFSDTYAAAGAKLIFHNIREAYNNPDNMEAKS
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
NMMTGAFYGGVAITGSGTTAVHALSYPLGGKYHIAHGVSNAILFAHVMEFNKDACSKRLA
CCCEEEEECCEEEECCCCCEEEEEECCCCCEEEEHHCCHHHHHHHHHHHHCHHHHHHHHH
ILCDAVYPELAGKSEDEKAQYMIDQIADIVKVTNIPTDLKEFGVKPEDLDFLVDAGSKQQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHEECCCCCCH
RLLVNNMKELSLDDIRNIYLKVLK
HHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SYQIKIPSCIFGGAGSIENVKAVIEKENAKKVIIFTDKGIRSTGLLDLLTDILEENKTE
CEEEECCCEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCH
YQVFDDLACEPSYQDVEKVMKEVENTSGDLIIAIGGGSVMDAAKLCCVLKDADYTIKDLL
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHC
NDPMLAKKQIKTVMIPTTCGTGSEATCNAIVAVPEEQSKKGIVNDSMIPDYVVLDSNMIR
CCCHHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCHHHH
KLPKSIVAATGVDALAHVVECFTSKKATPFSDTYAAAGAKLIFHNIREAYNNPDNMEAKS
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
NMMTGAFYGGVAITGSGTTAVHALSYPLGGKYHIAHGVSNAILFAHVMEFNKDACSKRLA
CCCEEEEECCEEEECCCCCEEEEEECCCCCEEEEHHCCHHHHHHHHHHHHCHHHHHHHHH
ILCDAVYPELAGKSEDEKAQYMIDQIADIVKVTNIPTDLKEFGVKPEDLDFLVDAGSKQQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHEECCCCCCH
RLLVNNMKELSLDDIRNIYLKVLK
HHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]