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The map label for this gene is yhaO [H]

Identifier: 238923552

GI number: 238923552

Start: 1081356

End: 1082420

Strand: Direct

Name: yhaO [H]

Synonym: EUBREC_1172

Alternate gene names: 238923552

Gene position: 1081356-1082420 (Clockwise)

Preceding gene: 238923551

Following gene: 238923553

Centisome position: 31.35

GC content: 43.76

Gene sequence:

>1065_bases
ATGAAAATTATCCACTGTGCAGACCTGCATCTGGATTCGAAGATGACCTCGAATCTGTCAAAGGAGCAGGCAAAAGAGAG
AAAAATGGAAATACTGCGTACATATTCAAGGATGATAGAGTACGCCAGAAATAACGATGTAAAGGCGATTATCATAGCAG
GCGATTTATTTGATACGAGAAATGTGTCAGCGACTGCCAGAAATCTGGTAAAGGATTCGATTACGTCAAATCCGGATATT
GATTTCTATTATCTTAAGGGTAATCACGACTCGGACAATTTCATATCGAAGCTCGATGAAATCCCTGAAAATCTTAAGCT
TTTTTCTAATCAGTGGACCTCATACAGCTATGGGAATATCACAATAACAGGTCTTGAGATAGACAAGTCTAACCAGGCTG
TTATGTACAATTCTCTTGTGCTCGACAATGACAATTACAACGTTGTCACTCTCCACGGACAGCTCGGTGATGAGATTTCC
ACAGGCGACCTTAAGAATAAGGGCATTGATTATCTCGCACTCGGTCATGTGCATGAGTATCAGAGCGGACAGCTTGACAA
CCGTGGCATGTACTGCTATAGCGGCTGCTTAGAGGGAAGAGGCTTTGATGAGTGCGGACAAAAAGGCTTTGTGGTGCTTG
ATATAGATGATGAGAAGCTCACGGCAGGCTTTAGCTTTGTACCGTTTGCGTACAGGAGCCTCTACACGCTGTATGTGGAT
GTGACAGGAGCTATGACCACACAGGATGTGGCTGTGAAGATGGAAAAGGCCATTTCGGACAGTGAATATTCATCGAGAAG
CATGGTAAAGTTCGTGCTTGTAGGTGAGGTGGACGTGGATTGTGAGATAAACACAGATTTCCTCAAGGATATGTTCGAGG
AATATTTCTACTATGAAAAGGTGTATGATGAGACAAGACTTCTCATCAATTACAGTGAATACGAAAAGGATGCATCACTT
AAGGGTGAGTTCATACGGATGGTGCTTGGCTCAGATATGACCGAGGAGCAGAAGTCTGAGGTCATCAGGTGTGGTATATC
GGCGCTTAGCGGGGAGGAGATTTAG

Upstream 100 bases:

>100_bases
GTGAATTGGCTGTAAATGATGCAACAAGGCTATGCGTAATGAATCTATGTGTAGTCTGTAATGATTTATAAACGTTCATA
TATCAAGAGGAATTGGAAAA

Downstream 100 bases:

>100_bases
AAATTGAAGTTAATAGCTTGTCACATAAACAACTTCGGAAAGCTGTCCGATCTTAATATCAATTTCAATGATGGAGTCAA
TGTCATAAACCAGCCAAACG

Product: DNA repair exonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKIIHCADLHLDSKMTSNLSKEQAKERKMEILRTYSRMIEYARNNDVKAIIIAGDLFDTRNVSATARNLVKDSITSNPDI
DFYYLKGNHDSDNFISKLDEIPENLKLFSNQWTSYSYGNITITGLEIDKSNQAVMYNSLVLDNDNYNVVTLHGQLGDEIS
TGDLKNKGIDYLALGHVHEYQSGQLDNRGMYCYSGCLEGRGFDECGQKGFVVLDIDDEKLTAGFSFVPFAYRSLYTLYVD
VTGAMTTQDVAVKMEKAISDSEYSSRSMVKFVLVGEVDVDCEINTDFLKDMFEEYFYYEKVYDETRLLINYSEYEKDASL
KGEFIRMVLGSDMTEEQKSEVIRCGISALSGEEI

Sequences:

>Translated_354_residues
MKIIHCADLHLDSKMTSNLSKEQAKERKMEILRTYSRMIEYARNNDVKAIIIAGDLFDTRNVSATARNLVKDSITSNPDI
DFYYLKGNHDSDNFISKLDEIPENLKLFSNQWTSYSYGNITITGLEIDKSNQAVMYNSLVLDNDNYNVVTLHGQLGDEIS
TGDLKNKGIDYLALGHVHEYQSGQLDNRGMYCYSGCLEGRGFDECGQKGFVVLDIDDEKLTAGFSFVPFAYRSLYTLYVD
VTGAMTTQDVAVKMEKAISDSEYSSRSMVKFVLVGEVDVDCEINTDFLKDMFEEYFYYEKVYDETRLLINYSEYEKDASL
KGEFIRMVLGSDMTEEQKSEVIRCGISALSGEEI
>Mature_354_residues
MKIIHCADLHLDSKMTSNLSKEQAKERKMEILRTYSRMIEYARNNDVKAIIIAGDLFDTRNVSATARNLVKDSITSNPDI
DFYYLKGNHDSDNFISKLDEIPENLKLFSNQWTSYSYGNITITGLEIDKSNQAVMYNSLVLDNDNYNVVTLHGQLGDEIS
TGDLKNKGIDYLALGHVHEYQSGQLDNRGMYCYSGCLEGRGFDECGQKGFVVLDIDDEKLTAGFSFVPFAYRSLYTLYVD
VTGAMTTQDVAVKMEKAISDSEYSSRSMVKFVLVGEVDVDCEINTDFLKDMFEEYFYYEKVYDETRLLINYSEYEKDASL
KGEFIRMVLGSDMTEEQKSEVIRCGISALSGEEI

Specific function: Sbccd Cleaves DNA Hairpin Structures. These Structures Can Inhibit DNA Replication And Are Intermediates In Certain DNA Recombination Reactions. The Complex Acts As A 3'->5' Double Strand Exonuclease That Can Open Hairpins. It Also Has A 5' Single-Strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR014576 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 40260; Mature: 40260

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIHCADLHLDSKMTSNLSKEQAKERKMEILRTYSRMIEYARNNDVKAIIIAGDLFDTR
CEEEEEECCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
NVSATARNLVKDSITSNPDIDFYYLKGNHDSDNFISKLDEIPENLKLFSNQWTSYSYGNI
CCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHCHHHHHHHHCCCCCEECCCE
TITGLEIDKSNQAVMYNSLVLDNDNYNVVTLHGQLGDEISTGDLKNKGIDYLALGHVHEY
EEEEEEECCCCCEEEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCEECC
QSGQLDNRGMYCYSGCLEGRGFDECGQKGFVVLDIDDEKLTAGFSFVPFAYRSLYTLYVD
CCCCCCCCCEEEEECCCCCCCHHHHCCCCEEEEEECCCCEECCCCCHHHHHHEEEEEEEE
VTGAMTTQDVAVKMEKAISDSEYSSRSMVKFVLVGEVDVDCEINTDFLKDMFEEYFYYEK
ECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECEECCEEECHHHHHHHHHHHHHHHH
VYDETRLLINYSEYEKDASLKGEFIRMVLGSDMTEEQKSEVIRCGISALSGEEI
HHCCEEEEEEEHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKIIHCADLHLDSKMTSNLSKEQAKERKMEILRTYSRMIEYARNNDVKAIIIAGDLFDTR
CEEEEEECCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
NVSATARNLVKDSITSNPDIDFYYLKGNHDSDNFISKLDEIPENLKLFSNQWTSYSYGNI
CCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHCHHHHHHHHCCCCCEECCCE
TITGLEIDKSNQAVMYNSLVLDNDNYNVVTLHGQLGDEISTGDLKNKGIDYLALGHVHEY
EEEEEEECCCCCEEEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCEECC
QSGQLDNRGMYCYSGCLEGRGFDECGQKGFVVLDIDDEKLTAGFSFVPFAYRSLYTLYVD
CCCCCCCCCEEEEECCCCCCCHHHHCCCCEEEEEECCCCEECCCCCHHHHHHEEEEEEEE
VTGAMTTQDVAVKMEKAISDSEYSSRSMVKFVLVGEVDVDCEINTDFLKDMFEEYFYYEK
ECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECEECCEEECHHHHHHHHHHHHHHHH
VYDETRLLINYSEYEKDASLKGEFIRMVLGSDMTEEQKSEVIRCGISALSGEEI
HHCCEEEEEEEHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]