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The map label for this gene is clpX [H]

Identifier: 238923551

GI number: 238923551

Start: 1079705

End: 1081234

Strand: Direct

Name: clpX [H]

Synonym: EUBREC_1171

Alternate gene names: 238923551

Gene position: 1079705-1081234 (Clockwise)

Preceding gene: 238923550

Following gene: 238923552

Centisome position: 31.3

GC content: 44.38

Gene sequence:

>1530_bases
ATGAATAATGATGATTTCAAGGAAGTACCTGACAATATTCAGGATAATAATGGAGAAACTACAAATAACATAGATAATAC
AAACGATAACAAGTCAAACGACTACGAGGATGTCTGCTATATCTGCCGCAGACCGGAGAGCGTGGCAGGAAAGATGATAC
ATATCCAGCCGAACCTGTGCATCTGCAACGATTGTATGCAAAAGACCTTTGACTCCATGAGCAACGGTAATTTTGGCAAC
CTCGGAAATCTGGGAAATATAAGCAATATGGATTTTGGCAATATGCCCAATATCAGCATGATAAATTTGTCAGATCTGAC
AGGAGGCATACCAAACAGCCAGAAGCTTAAGAAGAAAAAACCAAAGGAAGAGAAAAAGGTCGAGCCGATTCTTGACATTC
ACTCAATTCCTGCACCGCATAGGATCAAGGCAAGTCTTGATGACTATGTGGTAGGTCAGGAGCATGCAAAGAAGGTCATG
TCGGTTGCAGTATATAACCACTACAAGCGTGTCATGGCTGACAATAAGCATAAGGCGCAGGAAGAGAACACCACTGCAAA
GCAGGCTTCAAATAAATATGATGGTGTGGAGATTGAGAAATCAAATATGCTCATGATCGGACCTACAGGTTCAGGAAAGA
CATATCTCGTAAAGACTCTTGCAAAGCTTTTAGATGTGCCACTTGCCATAACAGATGCCACATCACTTACTGAGGCCGGA
TATATCGGTGACGATATCGAAAGTGTGGTAAGTAAGCTTCTTGCGGCTGCAGATAATGACGTGGAGAGAGCTGAGCACGG
TATCATTTTTATAGATGAGATAGACAAGCTTGCAAAGAAGAGAAATGCCAACCAGCGTGATGTGAGCGGAGAGTCAGTGC
AGCAGGGTATGCTTAAGCTTTTAGAGGGATCAGAGGTTGAGGTGCCGGTTGGTGCCAGCAGCAAGAATGCCATGGTTCCG
ATGACCACAGTTGACACGAGAAATATTCTCTTTATATGCGGAGGTGCTTTCCCGGGACTTGAGGATATCATAAAGGAGCG
CCTGAACAAGGAGGCTTCTATAGGCTTCAAGGCTGATTTGAAGGACAAGTATGATGGGGATGAAAACCTGCTCATGCAGG
CAACTGTTGATGATATCCGCAAATTCGGAATGATTCCTGAGTTTATCGGACGACTTCCTATCATGTTCTCACTTGAGGCG
CTCACCGAGGATATGCTTGTAAAGATATTGAAGGAGCCAAAGAATGCCATTATCAAGCAGTATCAGAAGCTCCTTGAGAT
GGATGAGGTAAGGCTTGAGTTCGACGATGATGCGCTTTATGCCATTGCCAAGATGGCAAAGGAAAAGAAGGTCGGAGCCA
GAGCTCTTCGTGCGATTATAGAGGATTTCATGCTCGATATCATGTATGAGATACCAAAGGATGACAATATCGGCACGGTT
ACAATCACTAAGGACTATGTGGAGAAGAAGGGTGGCCCGCTCATTCAGATGAGAGGTACACCTGAGCTTGCAGACAGTCA
GCACGTTTAA

Upstream 100 bases:

>100_bases
TCAAAAGCGCCTCAGCTTGCTTGCACGCATTTATTCAGTAGTGTATAATAGTTAAATGGCTGATAAAGCAGCTAAATGAT
ACAAAGGCGGTAATTCACCT

Downstream 100 bases:

>100_bases
TAGTTAAATGATTATGAAATTGTGAATTGGCTGTAAATGATGCAACAAGGCTATGCGTAATGAATCTATGTGTAGTCTGT
AATGATTTATAAACGTTCAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MNNDDFKEVPDNIQDNNGETTNNIDNTNDNKSNDYEDVCYICRRPESVAGKMIHIQPNLCICNDCMQKTFDSMSNGNFGN
LGNLGNISNMDFGNMPNISMINLSDLTGGIPNSQKLKKKKPKEEKKVEPILDIHSIPAPHRIKASLDDYVVGQEHAKKVM
SVAVYNHYKRVMADNKHKAQEENTTAKQASNKYDGVEIEKSNMLMIGPTGSGKTYLVKTLAKLLDVPLAITDATSLTEAG
YIGDDIESVVSKLLAAADNDVERAEHGIIFIDEIDKLAKKRNANQRDVSGESVQQGMLKLLEGSEVEVPVGASSKNAMVP
MTTVDTRNILFICGGAFPGLEDIIKERLNKEASIGFKADLKDKYDGDENLLMQATVDDIRKFGMIPEFIGRLPIMFSLEA
LTEDMLVKILKEPKNAIIKQYQKLLEMDEVRLEFDDDALYAIAKMAKEKKVGARALRAIIEDFMLDIMYEIPKDDNIGTV
TITKDYVEKKGGPLIQMRGTPELADSQHV

Sequences:

>Translated_509_residues
MNNDDFKEVPDNIQDNNGETTNNIDNTNDNKSNDYEDVCYICRRPESVAGKMIHIQPNLCICNDCMQKTFDSMSNGNFGN
LGNLGNISNMDFGNMPNISMINLSDLTGGIPNSQKLKKKKPKEEKKVEPILDIHSIPAPHRIKASLDDYVVGQEHAKKVM
SVAVYNHYKRVMADNKHKAQEENTTAKQASNKYDGVEIEKSNMLMIGPTGSGKTYLVKTLAKLLDVPLAITDATSLTEAG
YIGDDIESVVSKLLAAADNDVERAEHGIIFIDEIDKLAKKRNANQRDVSGESVQQGMLKLLEGSEVEVPVGASSKNAMVP
MTTVDTRNILFICGGAFPGLEDIIKERLNKEASIGFKADLKDKYDGDENLLMQATVDDIRKFGMIPEFIGRLPIMFSLEA
LTEDMLVKILKEPKNAIIKQYQKLLEMDEVRLEFDDDALYAIAKMAKEKKVGARALRAIIEDFMLDIMYEIPKDDNIGTV
TITKDYVEKKGGPLIQMRGTPELADSQHV
>Mature_509_residues
MNNDDFKEVPDNIQDNNGETTNNIDNTNDNKSNDYEDVCYICRRPESVAGKMIHIQPNLCICNDCMQKTFDSMSNGNFGN
LGNLGNISNMDFGNMPNISMINLSDLTGGIPNSQKLKKKKPKEEKKVEPILDIHSIPAPHRIKASLDDYVVGQEHAKKVM
SVAVYNHYKRVMADNKHKAQEENTTAKQASNKYDGVEIEKSNMLMIGPTGSGKTYLVKTLAKLLDVPLAITDATSLTEAG
YIGDDIESVVSKLLAAADNDVERAEHGIIFIDEIDKLAKKRNANQRDVSGESVQQGMLKLLEGSEVEVPVGASSKNAMVP
MTTVDTRNILFICGGAFPGLEDIIKERLNKEASIGFKADLKDKYDGDENLLMQATVDDIRKFGMIPEFIGRLPIMFSLEA
LTEDMLVKILKEPKNAIIKQYQKLLEMDEVRLEFDDDALYAIAKMAKEKKVGARALRAIIEDFMLDIMYEIPKDDNIGTV
TITKDYVEKKGGPLIQMRGTPELADSQHV

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=47.8658536585366, Blast_Score=281, Evalue=7e-76,
Organism=Escherichia coli, GI1786642, Length=385, Percent_Identity=48.5714285714286, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1790366, Length=236, Percent_Identity=33.8983050847458, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71982908, Length=431, Percent_Identity=33.6426914153132, Blast_Score=252, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI71982905, Length=317, Percent_Identity=40.0630914826498, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI71988663, Length=405, Percent_Identity=37.7777777777778, Blast_Score=245, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=254, Percent_Identity=39.7637795275591, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=421, Percent_Identity=38.7173396674584, Blast_Score=253, Evalue=6e-68,
Organism=Drosophila melanogaster, GI24648291, Length=315, Percent_Identity=46.6666666666667, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24648289, Length=315, Percent_Identity=46.6666666666667, Blast_Score=283, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 56590; Mature: 56590

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNDDFKEVPDNIQDNNGETTNNIDNTNDNKSNDYEDVCYICRRPESVAGKMIHIQPNLC
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCEEEECCCCE
ICNDCMQKTFDSMSNGNFGNLGNLGNISNMDFGNMPNISMINLSDLTGGIPNSQKLKKKK
EHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCHHHHHHCC
PKEEKKVEPILDIHSIPAPHRIKASLDDYVVGQEHAKKVMSVAVYNHYKRVMADNKHKAQ
CCHHHHCCCHHHHHCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EENTTAKQASNKYDGVEIEKSNMLMIGPTGSGKTYLVKTLAKLLDVPLAITDATSLTEAG
HHHHHHHHHCCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCC
YIGDDIESVVSKLLAAADNDVERAEHGIIFIDEIDKLAKKRNANQRDVSGESVQQGMLKL
CCCHHHHHHHHHHHHHCCCCHHHHHCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LEGSEVEVPVGASSKNAMVPMTTVDTRNILFICGGAFPGLEDIIKERLNKEASIGFKADL
HCCCCEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHCCCHHCCCEEECC
KDKYDGDENLLMQATVDDIRKFGMIPEFIGRLPIMFSLEALTEDMLVKILKEPKNAIIKQ
CCCCCCCCCEEEEHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQKLLEMDEVRLEFDDDALYAIAKMAKEKKVGARALRAIIEDFMLDIMYEIPKDDNIGTV
HHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
TITKDYVEKKGGPLIQMRGTPELADSQHV
EEEHHHHHHCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNNDDFKEVPDNIQDNNGETTNNIDNTNDNKSNDYEDVCYICRRPESVAGKMIHIQPNLC
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCEEEECCCCE
ICNDCMQKTFDSMSNGNFGNLGNLGNISNMDFGNMPNISMINLSDLTGGIPNSQKLKKKK
EHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCHHHHHHCC
PKEEKKVEPILDIHSIPAPHRIKASLDDYVVGQEHAKKVMSVAVYNHYKRVMADNKHKAQ
CCHHHHCCCHHHHHCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EENTTAKQASNKYDGVEIEKSNMLMIGPTGSGKTYLVKTLAKLLDVPLAITDATSLTEAG
HHHHHHHHHCCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCC
YIGDDIESVVSKLLAAADNDVERAEHGIIFIDEIDKLAKKRNANQRDVSGESVQQGMLKL
CCCHHHHHHHHHHHHHCCCCHHHHHCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LEGSEVEVPVGASSKNAMVPMTTVDTRNILFICGGAFPGLEDIIKERLNKEASIGFKADL
HCCCCEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHCCCHHCCCEEECC
KDKYDGDENLLMQATVDDIRKFGMIPEFIGRLPIMFSLEALTEDMLVKILKEPKNAIIKQ
CCCCCCCCCEEEEHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQKLLEMDEVRLEFDDDALYAIAKMAKEKKVGARALRAIIEDFMLDIMYEIPKDDNIGTV
HHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
TITKDYVEKKGGPLIQMRGTPELADSQHV
EEEHHHHHHCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA