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The map label for this gene is mcpB [H]

Identifier: 238923523

GI number: 238923523

Start: 1057123

End: 1059147

Strand: Direct

Name: mcpB [H]

Synonym: EUBREC_1143

Alternate gene names: 238923523

Gene position: 1057123-1059147 (Clockwise)

Preceding gene: 238923521

Following gene: 238923524

Centisome position: 30.64

GC content: 43.16

Gene sequence:

>2025_bases
ATGAGAGAAAGGGAGAAGGTAATGAAACAAAAAGGACAAAAGAAAACAACTTCCATTAAGACAAAGCTTCTGGGGACGAT
TCTTCCAGTTGTCATTGTGATTGGGCTTGTACTGGTAGGTGTGTCATATTTTGTATCAAAGCAGATAATCACAGAATATG
CCACAGATTTGCTGAATTCATCCATTGAAAATCAGGCAAATGAGATTGAATCCTGGCTGGGGGAAAATCTGGCAGCATTC
CAGATGGCAAAGGAGACGATTGAGGGGCTGGATGCAGATGATGCACAGCTTCAGGATATATTGGATAGATATTATGGCTA
TGATGACGACTATCCAAATGGACTTTACATCGCAGACGCTGATGGAAAACTGATGAAAGCAGGCGGATCAGATAAGACAG
AGAGCAATCCGACAGATTCCGTGTGGTATAAGGATGGTCTTACCAGATTAAACATGGCCTTTACTGATGCTTATACAAAT
GCGGATGAAGAGGCTGTTATCAGTGCGTCTGGTATTTTGAATGATGGCTCAGCGGCTATGAAGGTTATATCAGTAGACTT
GTCATTACAGCGTATCAGTATTATTGTAAACAGCTTTGTACAGATGGATGATGCGCAGGCGATTCTGGTAGATACCAAGG
ATGGCACAATACTTGCAGCCCGTGACAGCAGTTTGATTTTCTCAAAGTTAAGCGGGTCTGATGACAGCTTTTACAAGAGA
ATTGAAGAAAAAAGAGTATCCGGTGATTATGTTATGGAAGAGATTGATAACAGGATGGTTGCCTGTGCAGAGGTATCTGG
AACTGACTGGCTTTTGGTATCCTATGTTCCAACAGCCACAGTTTATTCGGGGATTAACACTGTCAGAATGGTAATGGCAC
TTATCGGAATAATTTCTCTTCTAATATTAGCTGTTATCATCGAGCGTACAGTCCATGTGGTAATAAAGCCTGTAAAAGAG
CTGACCAGCGTAATTACAGCCATGACAGATGGTGATTTCACAGTGAGCGTGGATGTAAAAAGTGATGATGAAATCGGTGT
GATGAGCCAGTGTGTACAGCACTTTATCCAGTCTATGAGGGGCATGATTTTGTCTATCCATGGAGTATCGGACAAGCTGC
ATGAGCAGGCGGATAACAGCAGCCTGATATCGGGTCAGATGTATGATGCATCCAGAACCCAGAGCCAGTCTATGCAGGAA
TTAAATAATACAGTAGAGCAGCTCTCACTTTCAGTTAATGAGATTGCAGAAAATGCCACAACTCTGGCAATGGTAGTTTC
AGACACCAGAGAAGAGGGCAGTCAGGTTGATTTGAAGATGAAGGACACTGTGGAAGTGTCAAGAAAGGGCAAGGCCGACA
TGCAGAATGTGGGCGATGCAATGCAGAATATCAATCAATCTGTGCTTAAACTGCAGCAGGCAATAGACAAGGTAGGAAAA
GCTTCTGAGGAGATTACAAATATCACAGGTGTAATCAGTGGAATTGCTGAGGAGACTAACTTACTTTCATTAAATGCTTC
TATAGAGGCAGCAAGAGCAGGGGAAGCCGGCAAGGGCTTTGCTGTTGTAGCTACTGAGATAGGCCAGCTTGCAAAGAACA
GCGCAGAGTCAGTACAAAATATCGAAAAACTTATATCAGAGATAAATGTACTGGTAAAGGATGCTGTATTGCAGGCGGAT
GACAGCGTTGAAAATATCAACAGCAGCGGCGAATTAGTCGGTGACGCTTTAAAGACTTTTGATGTCATATTTGGTAATAT
TGATGAGGTAAGCACCCTGGTTCGTCAGATGATTGAGAAAGTAGAAAAGGTAGATGAAGTGGCAAACAATGTAGCCGCCA
TTTCAGAGGAACAGGCAGCCAGCTCAGAGGAAATACTGGCTACGTCTGATAACATGGTAGAGCATGCTAATAGTATCACA
GGAAACAGTGAGACAGTAGCAAGCGATGCCAGGGAACTTACCACTTCGGCTAAGGAGCTGGCAAATCAGGTGGATGCATT
TAAGGTTGAAAAGGAGGGATACTAG

Upstream 100 bases:

>100_bases
AGATACATGGGAAGTAGTAAAAATTTATAAAATATAGTATTTTTATCATGAATGCTTGTGAAAAATAGACAAAGGGCTTA
TAATGTAAACTATACAAAAC

Downstream 100 bases:

>100_bases
AATGAAAAGGAAGCTGGCATACATGTTAAGTATATTGCTATGTGGAGTATTCCTGGCTACAGGCTGTGGCAGTCAGACCA
CAGGTGCAGGCAGCAGTAAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 674; Mature: 674

Protein sequence:

>674_residues
MREREKVMKQKGQKKTTSIKTKLLGTILPVVIVIGLVLVGVSYFVSKQIITEYATDLLNSSIENQANEIESWLGENLAAF
QMAKETIEGLDADDAQLQDILDRYYGYDDDYPNGLYIADADGKLMKAGGSDKTESNPTDSVWYKDGLTRLNMAFTDAYTN
ADEEAVISASGILNDGSAAMKVISVDLSLQRISIIVNSFVQMDDAQAILVDTKDGTILAARDSSLIFSKLSGSDDSFYKR
IEEKRVSGDYVMEEIDNRMVACAEVSGTDWLLVSYVPTATVYSGINTVRMVMALIGIISLLILAVIIERTVHVVIKPVKE
LTSVITAMTDGDFTVSVDVKSDDEIGVMSQCVQHFIQSMRGMILSIHGVSDKLHEQADNSSLISGQMYDASRTQSQSMQE
LNNTVEQLSLSVNEIAENATTLAMVVSDTREEGSQVDLKMKDTVEVSRKGKADMQNVGDAMQNINQSVLKLQQAIDKVGK
ASEEITNITGVISGIAEETNLLSLNASIEAARAGEAGKGFAVVATEIGQLAKNSAESVQNIEKLISEINVLVKDAVLQAD
DSVENINSSGELVGDALKTFDVIFGNIDEVSTLVRQMIEKVEKVDEVANNVAAISEEQAASSEEILATSDNMVEHANSIT
GNSETVASDARELTTSAKELANQVDAFKVEKEGY

Sequences:

>Translated_674_residues
MREREKVMKQKGQKKTTSIKTKLLGTILPVVIVIGLVLVGVSYFVSKQIITEYATDLLNSSIENQANEIESWLGENLAAF
QMAKETIEGLDADDAQLQDILDRYYGYDDDYPNGLYIADADGKLMKAGGSDKTESNPTDSVWYKDGLTRLNMAFTDAYTN
ADEEAVISASGILNDGSAAMKVISVDLSLQRISIIVNSFVQMDDAQAILVDTKDGTILAARDSSLIFSKLSGSDDSFYKR
IEEKRVSGDYVMEEIDNRMVACAEVSGTDWLLVSYVPTATVYSGINTVRMVMALIGIISLLILAVIIERTVHVVIKPVKE
LTSVITAMTDGDFTVSVDVKSDDEIGVMSQCVQHFIQSMRGMILSIHGVSDKLHEQADNSSLISGQMYDASRTQSQSMQE
LNNTVEQLSLSVNEIAENATTLAMVVSDTREEGSQVDLKMKDTVEVSRKGKADMQNVGDAMQNINQSVLKLQQAIDKVGK
ASEEITNITGVISGIAEETNLLSLNASIEAARAGEAGKGFAVVATEIGQLAKNSAESVQNIEKLISEINVLVKDAVLQAD
DSVENINSSGELVGDALKTFDVIFGNIDEVSTLVRQMIEKVEKVDEVANNVAAISEEQAASSEEILATSDNMVEHANSIT
GNSETVASDARELTTSAKELANQVDAFKVEKEGY
>Mature_674_residues
MREREKVMKQKGQKKTTSIKTKLLGTILPVVIVIGLVLVGVSYFVSKQIITEYATDLLNSSIENQANEIESWLGENLAAF
QMAKETIEGLDADDAQLQDILDRYYGYDDDYPNGLYIADADGKLMKAGGSDKTESNPTDSVWYKDGLTRLNMAFTDAYTN
ADEEAVISASGILNDGSAAMKVISVDLSLQRISIIVNSFVQMDDAQAILVDTKDGTILAARDSSLIFSKLSGSDDSFYKR
IEEKRVSGDYVMEEIDNRMVACAEVSGTDWLLVSYVPTATVYSGINTVRMVMALIGIISLLILAVIIERTVHVVIKPVKE
LTSVITAMTDGDFTVSVDVKSDDEIGVMSQCVQHFIQSMRGMILSIHGVSDKLHEQADNSSLISGQMYDASRTQSQSMQE
LNNTVEQLSLSVNEIAENATTLAMVVSDTREEGSQVDLKMKDTVEVSRKGKADMQNVGDAMQNINQSVLKLQQAIDKVGK
ASEEITNITGVISGIAEETNLLSLNASIEAARAGEAGKGFAVVATEIGQLAKNSAESVQNIEKLISEINVLVKDAVLQAD
DSVENINSSGELVGDALKTFDVIFGNIDEVSTLVRQMIEKVEKVDEVANNVAAISEEQAASSEEILATSDNMVEHANSIT
GNSETVASDARELTTSAKELANQVDAFKVEKEGY

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=368, Percent_Identity=26.0869565217391, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI2367378, Length=329, Percent_Identity=29.1793313069909, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788194, Length=385, Percent_Identity=26.7532467532467, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788195, Length=315, Percent_Identity=27.6190476190476, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789453, Length=304, Percent_Identity=25.6578947368421, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 73005; Mature: 73005

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREREKVMKQKGQKKTTSIKTKLLGTILPVVIVIGLVLVGVSYFVSKQIITEYATDLLNS
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIENQANEIESWLGENLAAFQMAKETIEGLDADDAQLQDILDRYYGYDDDYPNGLYIADA
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECC
DGKLMKAGGSDKTESNPTDSVWYKDGLTRLNMAFTDAYTNADEEAVISASGILNDGSAAM
CCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCHHEEECCCCCCCCHHHE
KVISVDLSLQRISIIVNSFVQMDDAQAILVDTKDGTILAARDSSLIFSKLSGSDDSFYKR
EHHEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHHHHHCCCCCHHHHHH
IEEKRVSGDYVMEEIDNRMVACAEVSGTDWLLVSYVPTATVYSGINTVRMVMALIGIISL
HHHHHCCHHHHHHHHCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LILAVIIERTVHVVIKPVKELTSVITAMTDGDFTVSVDVKSDDEIGVMSQCVQHFIQSMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
GMILSIHGVSDKLHEQADNSSLISGQMYDASRTQSQSMQELNNTVEQLSLSVNEIAENAT
HHEEEEECCCHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TLAMVVSDTREEGSQVDLKMKDTVEVSRKGKADMQNVGDAMQNINQSVLKLQQAIDKVGK
HEEHEEHHHHCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASEEITNITGVISGIAEETNLLSLNASIEAARAGEAGKGFAVVATEIGQLAKNSAESVQN
HHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IEKLISEINVLVKDAVLQADDSVENINSSGELVGDALKTFDVIFGNIDEVSTLVRQMIEK
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VEKVDEVANNVAAISEEQAASSEEILATSDNMVEHANSITGNSETVASDARELTTSAKEL
HHHHHHHHHHHHHHCHHHCCCCCHHEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ANQVDAFKVEKEGY
HHHHHHEEECCCCC
>Mature Secondary Structure
MREREKVMKQKGQKKTTSIKTKLLGTILPVVIVIGLVLVGVSYFVSKQIITEYATDLLNS
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIENQANEIESWLGENLAAFQMAKETIEGLDADDAQLQDILDRYYGYDDDYPNGLYIADA
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECC
DGKLMKAGGSDKTESNPTDSVWYKDGLTRLNMAFTDAYTNADEEAVISASGILNDGSAAM
CCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCHHEEECCCCCCCCHHHE
KVISVDLSLQRISIIVNSFVQMDDAQAILVDTKDGTILAARDSSLIFSKLSGSDDSFYKR
EHHEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHHHHHCCCCCHHHHHH
IEEKRVSGDYVMEEIDNRMVACAEVSGTDWLLVSYVPTATVYSGINTVRMVMALIGIISL
HHHHHCCHHHHHHHHCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LILAVIIERTVHVVIKPVKELTSVITAMTDGDFTVSVDVKSDDEIGVMSQCVQHFIQSMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
GMILSIHGVSDKLHEQADNSSLISGQMYDASRTQSQSMQELNNTVEQLSLSVNEIAENAT
HHEEEEECCCHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TLAMVVSDTREEGSQVDLKMKDTVEVSRKGKADMQNVGDAMQNINQSVLKLQQAIDKVGK
HEEHEEHHHHCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASEEITNITGVISGIAEETNLLSLNASIEAARAGEAGKGFAVVATEIGQLAKNSAESVQN
HHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IEKLISEINVLVKDAVLQADDSVENINSSGELVGDALKTFDVIFGNIDEVSTLVRQMIEK
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VEKVDEVANNVAAISEEQAASSEEILATSDNMVEHANSITGNSETVASDARELTTSAKEL
HHHHHHHHHHHHHHCHHHCCCCCHHEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ANQVDAFKVEKEGY
HHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]