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The map label for this gene is cbiL [H]

Identifier: 238923513

GI number: 238923513

Start: 1047967

End: 1048740

Strand: Direct

Name: cbiL [H]

Synonym: EUBREC_1133

Alternate gene names: 238923513

Gene position: 1047967-1048740 (Clockwise)

Preceding gene: 238923512

Following gene: 238923514

Centisome position: 30.38

GC content: 41.86

Gene sequence:

>774_bases
ATGTGGTATAGAAAGCAGGAAATTATAAAGATGGACAAGCAGATAGAAAGAGCAGGTGATGACAATAAAAATAATATTGG
TGTGTTATATGGCATCGGTGTAGGTCCGGGAGATCCCGAGCTTATGACTTTAAAGGCTATTAATACAATAAAAGCATGTG
ATATAATTGCAATCCCTGCAGTTTCAAAAGAGGAATGCTATGCGTACAGCATAGTGCAGGCTGTTTTACCGGAGATAGAG
AAAAAACAGATTATGTGCACTCCGTTTCCAATGATAAAGGACAAGGAAAAGCTTACTATATCACACAATAAGATATACTG
TGACATAGTAAGTGAGCTTGAAGATGGGAAAAATGTGGCAATGCTTACAATCGGCGATCCAAGCGTGTATTCGACATATA
TGTATATCCATAAGCGTGTCATGCAGGCAGGTTTTACGGCAGTGATGATAAGCGGTGTGCCATCGTTTTGTGCAGCTGCA
GCGCGGCTTGGCATTTCGCTTGGAGAGATGATGGATGAGATACATATCATACCGGCTTCGTATGATGTGAGGGATACTGT
GGGCTACGGTGGAACCTGTGTATACATGAAATCCGGAAAGAAGCTTGCAGAGCTTATAGAGGTGCTTCGCACAGGAGATG
CTATCAGAAAAAAGAAAATGACAGTGTATGGTGTGACAAACTGTGGCATGGAGTCTGAGCGTGTGTACAGGGGGCTGGAT
GAGCTTACTGAAGCAAAAGGATATCTGACAATAGTTATAGTGAAATATAGCTAA

Upstream 100 bases:

>100_bases
TGATAGTTGTGGATGATAATGGTGCAGAGACGATAATTGATACAAGAAGAATATATGATATCGATTTGTGATGATTTTGT
TAGGAATGCATTACTTGTAA

Downstream 100 bases:

>100_bases
AATGGGAGTTTACTTTTTGTGCACAATTGCTATAATAGTATGGTGAACCGAATATTTATATATCTGAATATAGAAAAGAG
CTGAAATATCACATGAGTAT

Product: precorrin-2 methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MWYRKQEIIKMDKQIERAGDDNKNNIGVLYGIGVGPGDPELMTLKAINTIKACDIIAIPAVSKEECYAYSIVQAVLPEIE
KKQIMCTPFPMIKDKEKLTISHNKIYCDIVSELEDGKNVAMLTIGDPSVYSTYMYIHKRVMQAGFTAVMISGVPSFCAAA
ARLGISLGEMMDEIHIIPASYDVRDTVGYGGTCVYMKSGKKLAELIEVLRTGDAIRKKKMTVYGVTNCGMESERVYRGLD
ELTEAKGYLTIVIVKYS

Sequences:

>Translated_257_residues
MWYRKQEIIKMDKQIERAGDDNKNNIGVLYGIGVGPGDPELMTLKAINTIKACDIIAIPAVSKEECYAYSIVQAVLPEIE
KKQIMCTPFPMIKDKEKLTISHNKIYCDIVSELEDGKNVAMLTIGDPSVYSTYMYIHKRVMQAGFTAVMISGVPSFCAAA
ARLGISLGEMMDEIHIIPASYDVRDTVGYGGTCVYMKSGKKLAELIEVLRTGDAIRKKKMTVYGVTNCGMESERVYRGLD
ELTEAKGYLTIVIVKYS
>Mature_257_residues
MWYRKQEIIKMDKQIERAGDDNKNNIGVLYGIGVGPGDPELMTLKAINTIKACDIIAIPAVSKEECYAYSIVQAVLPEIE
KKQIMCTPFPMIKDKEKLTISHNKIYCDIVSELEDGKNVAMLTIGDPSVYSTYMYIHKRVMQAGFTAVMISGVPSFCAAA
ARLGISLGEMMDEIHIIPASYDVRDTVGYGGTCVYMKSGKKLAELIEVLRTGDAIRKKKMTVYGVTNCGMESERVYRGLD
ELTEAKGYLTIVIVKYS

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 28540; Mature: 28540

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWYRKQEIIKMDKQIERAGDDNKNNIGVLYGIGVGPGDPELMTLKAINTIKACDIIAIPA
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEEEEECCHHHHCCEEEECC
VSKEECYAYSIVQAVLPEIEKKQIMCTPFPMIKDKEKLTISHNKIYCDIVSELEDGKNVA
CCHHHHHHHHHHHHHHCCHHCCCEEECCCCCCCCCCEEEEECCEEEEEEHHHHCCCCCEE
MLTIGDPSVYSTYMYIHKRVMQAGFTAVMISGVPSFCAAAARLGISLGEMMDEIHIIPAS
EEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHEEEEECC
YDVRDTVGYGGTCVYMKSGKKLAELIEVLRTGDAIRKKKMTVYGVTNCGMESERVYRGLD
CCCHHCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHCCEEEEEECCCCCCHHHHHHHHH
ELTEAKGYLTIVIVKYS
HHHHCCCEEEEEEEEEC
>Mature Secondary Structure
MWYRKQEIIKMDKQIERAGDDNKNNIGVLYGIGVGPGDPELMTLKAINTIKACDIIAIPA
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEEEEECCHHHHCCEEEECC
VSKEECYAYSIVQAVLPEIEKKQIMCTPFPMIKDKEKLTISHNKIYCDIVSELEDGKNVA
CCHHHHHHHHHHHHHHCCHHCCCEEECCCCCCCCCCEEEEECCEEEEEEHHHHCCCCCEE
MLTIGDPSVYSTYMYIHKRVMQAGFTAVMISGVPSFCAAAARLGISLGEMMDEIHIIPAS
EEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHEEEEECC
YDVRDTVGYGGTCVYMKSGKKLAELIEVLRTGDAIRKKKMTVYGVTNCGMESERVYRGLD
CCCHHCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHCCEEEEEECCCCCCHHHHHHHHH
ELTEAKGYLTIVIVKYS
HHHHCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]