Click here to switch to the map view.

The map label for this gene is exuR [H]

Identifier: 238923453

GI number: 238923453

Start: 977794

End: 978804

Strand: Direct

Name: exuR [H]

Synonym: EUBREC_1073

Alternate gene names: 238923453

Gene position: 977794-978804 (Clockwise)

Preceding gene: 238923451

Following gene: 238923454

Centisome position: 28.34

GC content: 44.11

Gene sequence:

>1011_bases
ATGGTATCACTGAAAGACATAGCACAAAGATGTGGTGTTTCGACAGCGACAGTAAGCAAGGCATTACATGACCAGAAGGA
TATTGGCGCTGAGACCAAAAACAGAATAAAGAAGATAGCTAAGGAAATGGGATATCTTCCTAATGCTGCGGCCAGAGTTC
TTAAGACAAACGAGTCGAACAACATCGGAGTACTGTATTTCGATGAGGCGGCGATGGGGCTTACGCATGAGTATTTTGCC
GGAGTGCTAAACGGAATCAAGGCACAGGCTGAGATGCTTGGATATGATATTACATTTATCAATACAAGTCCGGTCGGAAA
AAAATTATCATACCTGGAGCACTGTAAGTACAGAAATTTCGATGGAGTCGTAATCGTATGTGCAAGGTTTCAGGACAATG
AGGTGCAGGAACTGATGAGCAGCGACATACCGGTGGTCACAATTGACTACGTACACTATAGCTGTTCGGCAGTAAGTTCC
AACAATGTAAAGTGTATGGGCGAGCTGCTTGATTACATAATAAGCATGGGACATAAGAAAATCGCTTACATACATGGACA
GGATTTTTCGAGTGTTACACGTGACAGGCTGGCAGCATATTACAGGGCACTTGAGAAGCATGGAATAGATATTCCTGAGG
AGTATGTCAGGGAAGCAAGGTATCTGGAAACAGAGGATGTTGCAAATCAGACAGAATATTTACTCGATTTACCTGACAAA
CCTACATGTATCATCTATCCGGATGACACGGCGGCAATCGGAGGCATCAATGTTATAAGAAGCAGAGGGCTTAGGATTCC
GGAGGATATATCAATAGCAGGATACGATGGTACAAGAGTTTCACAGATGCTAAGCCCGAAGCTCACCACTATCAGACAGG
ACACTGACAAGATAGGCAGGGAGGCAGCGGACAGGTTGATAAGCATCATTAAAAAGCCTAAAACAGCACTTGTGGAGAGA
GCTGTTGTTGAAGGAATTTTGCTGGAGGGGGAATCCGTAGGCAGAATTTAA

Upstream 100 bases:

>100_bases
AAATGTTGAAAATGTAAATTAGGGGTTGCAATAATAATGAATTGTGGTATAGTGAAGATACGAAAACGATTAAGAAACCA
ATTCGAAATGAGGAAACGAT

Downstream 100 bases:

>100_bases
TATATTTTACTACTTTTTTACTAACATTTACTAACAGGTTTAAACCTGAAGCGAGAAGGAGGATTTTTCTATGAAAAAGA
AACTCGTAAGCGCATTACTT

Product: transcriptional regulator (LacI family)

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MVSLKDIAQRCGVSTATVSKALHDQKDIGAETKNRIKKIAKEMGYLPNAAARVLKTNESNNIGVLYFDEAAMGLTHEYFA
GVLNGIKAQAEMLGYDITFINTSPVGKKLSYLEHCKYRNFDGVVIVCARFQDNEVQELMSSDIPVVTIDYVHYSCSAVSS
NNVKCMGELLDYIISMGHKKIAYIHGQDFSSVTRDRLAAYYRALEKHGIDIPEEYVREARYLETEDVANQTEYLLDLPDK
PTCIIYPDDTAAIGGINVIRSRGLRIPEDISIAGYDGTRVSQMLSPKLTTIRQDTDKIGREAADRLISIIKKPKTALVER
AVVEGILLEGESVGRI

Sequences:

>Translated_336_residues
MVSLKDIAQRCGVSTATVSKALHDQKDIGAETKNRIKKIAKEMGYLPNAAARVLKTNESNNIGVLYFDEAAMGLTHEYFA
GVLNGIKAQAEMLGYDITFINTSPVGKKLSYLEHCKYRNFDGVVIVCARFQDNEVQELMSSDIPVVTIDYVHYSCSAVSS
NNVKCMGELLDYIISMGHKKIAYIHGQDFSSVTRDRLAAYYRALEKHGIDIPEEYVREARYLETEDVANQTEYLLDLPDK
PTCIIYPDDTAAIGGINVIRSRGLRIPEDISIAGYDGTRVSQMLSPKLTTIRQDTDKIGREAADRLISIIKKPKTALVER
AVVEGILLEGESVGRI
>Mature_336_residues
MVSLKDIAQRCGVSTATVSKALHDQKDIGAETKNRIKKIAKEMGYLPNAAARVLKTNESNNIGVLYFDEAAMGLTHEYFA
GVLNGIKAQAEMLGYDITFINTSPVGKKLSYLEHCKYRNFDGVVIVCARFQDNEVQELMSSDIPVVTIDYVHYSCSAVSS
NNVKCMGELLDYIISMGHKKIAYIHGQDFSSVTRDRLAAYYRALEKHGIDIPEEYVREARYLETEDVANQTEYLLDLPDK
PTCIIYPDDTAAIGGINVIRSRGLRIPEDISIAGYDGTRVSQMLSPKLTTIRQDTDKIGREAADRLISIIKKPKTALVER
AVVEGILLEGESVGRI

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=28.8288288288288, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790369, Length=303, Percent_Identity=30.03300330033, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=28.4431137724551, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=25.9493670886076, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786540, Length=314, Percent_Identity=27.3885350318471, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789068, Length=327, Percent_Identity=25.3822629969419, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994940, Length=314, Percent_Identity=26.7515923566879, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788474, Length=301, Percent_Identity=24.9169435215947, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789456, Length=322, Percent_Identity=26.0869565217391, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790715, Length=323, Percent_Identity=29.1021671826625, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789202, Length=297, Percent_Identity=24.5791245791246, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787906, Length=328, Percent_Identity=23.1707317073171, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37308; Mature: 37308

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKDIAQRCGVSTATVSKALHDQKDIGAETKNRIKKIAKEMGYLPNAAARVLKTNESN
CCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCC
NIGVLYFDEAAMGLTHEYFAGVLNGIKAQAEMLGYDITFINTSPVGKKLSYLEHCKYRNF
CEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHCCCCC
DGVVIVCARFQDNEVQELMSSDIPVVTIDYVHYSCSAVSSNNVKCMGELLDYIISMGHKK
CCEEEEEEECCCHHHHHHHHCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCE
IAYIHGQDFSSVTRDRLAAYYRALEKHGIDIPEEYVREARYLETEDVANQTEYLLDLPDK
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCHHHHEEECCCC
PTCIIYPDDTAAIGGINVIRSRGLRIPEDISIAGYDGTRVSQMLSPKLTTIRQDTDKIGR
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHH
EAADRLISIIKKPKTALVERAVVEGILLEGESVGRI
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVSLKDIAQRCGVSTATVSKALHDQKDIGAETKNRIKKIAKEMGYLPNAAARVLKTNESN
CCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCC
NIGVLYFDEAAMGLTHEYFAGVLNGIKAQAEMLGYDITFINTSPVGKKLSYLEHCKYRNF
CEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHCCCCC
DGVVIVCARFQDNEVQELMSSDIPVVTIDYVHYSCSAVSSNNVKCMGELLDYIISMGHKK
CCEEEEEEECCCHHHHHHHHCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCE
IAYIHGQDFSSVTRDRLAAYYRALEKHGIDIPEEYVREARYLETEDVANQTEYLLDLPDK
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCHHHHEEECCCC
PTCIIYPDDTAAIGGINVIRSRGLRIPEDISIAGYDGTRVSQMLSPKLTTIRQDTDKIGR
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHH
EAADRLISIIKKPKTALVERAVVEGILLEGESVGRI
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]