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The map label for this gene is clpX

Identifier: 238923370

GI number: 238923370

Start: 884416

End: 885687

Strand: Direct

Name: clpX

Synonym: EUBREC_0990

Alternate gene names: 238923370

Gene position: 884416-885687 (Clockwise)

Preceding gene: 238923369

Following gene: 238923371

Centisome position: 25.64

GC content: 43.79

Gene sequence:

>1272_bases
ATGGCAGGAAAAAACGACGGAAAGATTCGCTGCTCATTTTGCGGTAAGACACAGGACCAGGTAAATCGTTTGATTTCCGG
ACCTAATGGAGCTTTTATCTGCGATGAGTGTATAGATATATGTGCCGAGATTCTTGAGGAAGAAGGCGTAGATGGCCATG
AGGACAAAAGCAGCGCTAAGGATGATATAAATCTTGTTACTCCGGAGGAGCTTAAGGCGTTTCTGGACGATTATGTAATA
GGACAGGACCAGGCAAAGAAGGTGCTTTCGGTTGCTGTTTACAATCACTATAAGAGAGTTCTGGCAGGTGATACATCAGA
TGTAGAGCTTCAGAAGAGTAATATTCTCATGCTTGGACCTACAGGCTCAGGAAAGACACTTCTTGCGCAGACACTTGCCA
GAGTGATAAATGTTCCATTTGCTATCGCTGATGCTACAACACTTACAGAGGCAGGATACGTAGGTGAGGATGTGGAGAAT
ATCCTATTAAAGCTTATTCAGGCGGCAGATTATGATATCGAGCGTGCAGAGCATGGTATCATTTATATAGATGAGATAGA
TAAAATTACAAAGAAATCAGAGAATGTCTCAATCACCAGAGATGTGTCAGGCGAGGGTGTACAGCAGGCTCTTTTAAAGA
TTCTTGAGGGCACAGAAGCATCTGTACCGCCACAGGGCGGAAGAAAGCATCCGCAGCAGGAGCTTATTCCTATTGATACT
ACTAATATACTTTTTATCTGCGGTGGAGCATTTGATGGTCTGGAAAAAATTATCGACAGTCGTATGGATACATCATCTAT
AGGCTTCAATTCAGATGTAAAGTCAAAGACAGAGCTCAATGTAGGAGAGGCGTTTAAGCATGCACTTCCACAGGATTTTG
TAAAGTTTGGATTGATTCCTGAGTTTATCGGACGTGTACCTATTACCGTTTCTCTCGAGGCACTCGACAGGGATGCACTT
ATCCGTATACTTAAGGAGCCTAAGAACTCGCTTATCAAGCAGTACACCAAGCTTTTTGAACTTGACGGAGTAGGTCTTGA
GTTCACAGACGATGCAGTAAATGCCATCGCTGACAAGGCACTTGAGAGAAAGACAGGAGCCAGAGGACTTCGTGCCATCA
TGGAGGCTGTTATGCTTGACCTTATGTATCGTATACCATCAGACAAGAGCATCAGCAAGTGCGTAATCGACAAGGATACA
GTTGAGGAAAACTTAAAGCTTGATGGTGATTGCGTGCCTGAGGCATATATCGAGGAAAAAGCGGCATCGTAA

Upstream 100 bases:

>100_bases
GTCTCATAGACAGTGTAATAACAAACAGATAATCAGAAGTTAGATGAATTTAAGAGGGTACCCCATATGGGATGCCCTCA
TGCAATAAAAGGAGTTAATA

Downstream 100 bases:

>100_bases
GTACATGGCGGTATTTTACAAAAGATACAGCATCGGATAATATAAATTGCACAGCGGTTTGTTATGCATGGCTGTGCAAT
AATACAGGAGATATAAGTGG

Product: ATP-dependent protease ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MAGKNDGKIRCSFCGKTQDQVNRLISGPNGAFICDECIDICAEILEEEGVDGHEDKSSAKDDINLVTPEELKAFLDDYVI
GQDQAKKVLSVAVYNHYKRVLAGDTSDVELQKSNILMLGPTGSGKTLLAQTLARVINVPFAIADATTLTEAGYVGEDVEN
ILLKLIQAADYDIERAEHGIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTEASVPPQGGRKHPQQELIPIDT
TNILFICGGAFDGLEKIIDSRMDTSSIGFNSDVKSKTELNVGEAFKHALPQDFVKFGLIPEFIGRVPITVSLEALDRDAL
IRILKEPKNSLIKQYTKLFELDGVGLEFTDDAVNAIADKALERKTGARGLRAIMEAVMLDLMYRIPSDKSISKCVIDKDT
VEENLKLDGDCVPEAYIEEKAAS

Sequences:

>Translated_423_residues
MAGKNDGKIRCSFCGKTQDQVNRLISGPNGAFICDECIDICAEILEEEGVDGHEDKSSAKDDINLVTPEELKAFLDDYVI
GQDQAKKVLSVAVYNHYKRVLAGDTSDVELQKSNILMLGPTGSGKTLLAQTLARVINVPFAIADATTLTEAGYVGEDVEN
ILLKLIQAADYDIERAEHGIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTEASVPPQGGRKHPQQELIPIDT
TNILFICGGAFDGLEKIIDSRMDTSSIGFNSDVKSKTELNVGEAFKHALPQDFVKFGLIPEFIGRVPITVSLEALDRDAL
IRILKEPKNSLIKQYTKLFELDGVGLEFTDDAVNAIADKALERKTGARGLRAIMEAVMLDLMYRIPSDKSISKCVIDKDT
VEENLKLDGDCVPEAYIEEKAAS
>Mature_422_residues
AGKNDGKIRCSFCGKTQDQVNRLISGPNGAFICDECIDICAEILEEEGVDGHEDKSSAKDDINLVTPEELKAFLDDYVIG
QDQAKKVLSVAVYNHYKRVLAGDTSDVELQKSNILMLGPTGSGKTLLAQTLARVINVPFAIADATTLTEAGYVGEDVENI
LLKLIQAADYDIERAEHGIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTEASVPPQGGRKHPQQELIPIDTT
NILFICGGAFDGLEKIIDSRMDTSSIGFNSDVKSKTELNVGEAFKHALPQDFVKFGLIPEFIGRVPITVSLEALDRDALI
RILKEPKNSLIKQYTKLFELDGVGLEFTDDAVNAIADKALERKTGARGLRAIMEAVMLDLMYRIPSDKSISKCVIDKDTV
EENLKLDGDCVPEAYIEEKAAS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=326, Percent_Identity=48.159509202454, Blast_Score=302, Evalue=4e-82,
Organism=Escherichia coli, GI1786642, Length=399, Percent_Identity=62.1553884711779, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI1790366, Length=234, Percent_Identity=35.4700854700855, Blast_Score=104, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71982908, Length=301, Percent_Identity=44.8504983388704, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=301, Percent_Identity=44.8504983388704, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=429, Percent_Identity=37.0629370629371, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI71988660, Length=268, Percent_Identity=38.0597014925373, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=40.9836065573771, Blast_Score=280, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24648291, Length=302, Percent_Identity=47.0198675496689, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24648289, Length=302, Percent_Identity=47.0198675496689, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_EUBR3 (C4ZGF5)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002936886.1
- GeneID:   7964964
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_0990
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46225; Mature: 46094

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKNDGKIRCSFCGKTQDQVNRLISGPNGAFICDECIDICAEILEEEGVDGHEDKSSAK
CCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCC
DDINLVTPEELKAFLDDYVIGQDQAKKVLSVAVYNHYKRVLAGDTSDVELQKSNILMLGP
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEECC
TGSGKTLLAQTLARVINVPFAIADATTLTEAGYVGEDVENILLKLIQAADYDIERAEHGI
CCCCHHHHHHHHHHHHCCCHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCCCE
IYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTEASVPPQGGRKHPQQELIPIDT
EEEECHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCC
TNILFICGGAFDGLEKIIDSRMDTSSIGFNSDVKSKTELNVGEAFKHALPQDFVKFGLIP
CCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCHHHHHHHHCHHHHHHHCCCH
EFIGRVPITVSLEALDRDALIRILKEPKNSLIKQYTKLFELDGVGLEFTDDAVNAIADKA
HHHCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHH
LERKTGARGLRAIMEAVMLDLMYRIPSDKSISKCVIDKDTVEENLKLDGDCVPEAYIEEK
HHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCCCCCCCCCHHHHHHH
AAS
CCC
>Mature Secondary Structure 
AGKNDGKIRCSFCGKTQDQVNRLISGPNGAFICDECIDICAEILEEEGVDGHEDKSSAK
CCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCC
DDINLVTPEELKAFLDDYVIGQDQAKKVLSVAVYNHYKRVLAGDTSDVELQKSNILMLGP
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEECC
TGSGKTLLAQTLARVINVPFAIADATTLTEAGYVGEDVENILLKLIQAADYDIERAEHGI
CCCCHHHHHHHHHHHHCCCHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCCCE
IYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTEASVPPQGGRKHPQQELIPIDT
EEEECHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCC
TNILFICGGAFDGLEKIIDSRMDTSSIGFNSDVKSKTELNVGEAFKHALPQDFVKFGLIP
CCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCHHHHHHHHCHHHHHHHCCCH
EFIGRVPITVSLEALDRDALIRILKEPKNSLIKQYTKLFELDGVGLEFTDDAVNAIADKA
HHHCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHH
LERKTGARGLRAIMEAVMLDLMYRIPSDKSISKCVIDKDTVEENLKLDGDCVPEAYIEEK
HHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCCCCCCCCCHHHHHHH
AAS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA