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The map label for this gene is trxA [H]

Identifier: 238923286

GI number: 238923286

Start: 803044

End: 803361

Strand: Direct

Name: trxA [H]

Synonym: EUBREC_0897

Alternate gene names: 238923286

Gene position: 803044-803361 (Clockwise)

Preceding gene: 238923285

Following gene: 238923287

Centisome position: 23.28

GC content: 43.71

Gene sequence:

>318_bases
ATGGCAGCAAGAATTTCAAAGGCTGATTTCGATGAAAAAGTATTAAAAAGCAAGCTTCCGGTAATTGTTGATTTTTACTC
GGATTCATGTGTGGCCTGCAAGAAGCTGGCACCGGTTCTCGGAGATATCGAGGATGATTATGAGGATAAGCTTCACGTAT
ACAAGGTCAACACAAACTTTGACGGAGAGCTCGCTGATGAGTATGAGGTGACTGCGAATCCGACACTGCTTTTCGTAAAA
GACGCAGAGGTCTTAGATAGAAAGGTCGGCGCACAAAAGCCTGCCGATTTGAAGGCATGGGTTGAAGAATTATTATAG

Upstream 100 bases:

>100_bases
TTCCAAGAAGCATGAAGGAAGAGGGACACAAGATACTTAAGCTCGAGGACAACGAGGATGGAACATACACTCTTTACGTC
AGAAAGGTTGAGGACTAATC

Downstream 100 bases:

>100_bases
TCTTTAGATTATTATATAAAGCAGTCTGATACAGGATAATAACACATACAGATACCACAATCTGTGACACAGGAGGAAAT
AAAATGACTATCACAGTAGC

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MAARISKADFDEKVLKSKLPVIVDFYSDSCVACKKLAPVLGDIEDDYEDKLHVYKVNTNFDGELADEYEVTANPTLLFVK
DAEVLDRKVGAQKPADLKAWVEELL

Sequences:

>Translated_105_residues
MAARISKADFDEKVLKSKLPVIVDFYSDSCVACKKLAPVLGDIEDDYEDKLHVYKVNTNFDGELADEYEVTANPTLLFVK
DAEVLDRKVGAQKPADLKAWVEELL
>Mature_104_residues
AARISKADFDEKVLKSKLPVIVDFYSDSCVACKKLAPVLGDIEDDYEDKLHVYKVNTNFDGELADEYEVTANPTLLFVKD
AEVLDRKVGAQKPADLKAWVEELL

Specific function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=97, Percent_Identity=37.1134020618557, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082331, Length=93, Percent_Identity=39.7849462365591, Blast_Score=73, Evalue=3e-15,
Organism=Escherichia coli, GI1788936, Length=94, Percent_Identity=32.9787234042553, Blast_Score=70, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212646193, Length=97, Percent_Identity=34.020618556701, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28573567, Length=98, Percent_Identity=33.6734693877551, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11779; Mature: 11648

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARISKADFDEKVLKSKLPVIVDFYSDSCVACKKLAPVLGDIEDDYEDKLHVYKVNTNF
CCCCCCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
DGELADEYEVTANPTLLFVKDAEVLDRKVGAQKPADLKAWVEELL
CCCCCCCEEECCCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHHC
>Mature Secondary Structure 
AARISKADFDEKVLKSKLPVIVDFYSDSCVACKKLAPVLGDIEDDYEDKLHVYKVNTNF
CCCCCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
DGELADEYEVTANPTLLFVKDAEVLDRKVGAQKPADLKAWVEELL
CCCCCCCEEECCCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA