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The map label for this gene is araD [H]

Identifier: 238923079

GI number: 238923079

Start: 612977

End: 613672

Strand: Direct

Name: araD [H]

Synonym: EUBREC_0669

Alternate gene names: 238923079

Gene position: 612977-613672 (Clockwise)

Preceding gene: 238923078

Following gene: 238923080

Centisome position: 17.77

GC content: 47.56

Gene sequence:

>696_bases
ATGCTTGAAGAATTAAAGAAACAGGTTTACGAAGCAAACATGGAGCTCCCAAGAAGAGGGCTTATCACATATACATGGGG
CAATGTCAGTGGAATTGACAGGGAAACAGGCTATTTTGTCATCAAGCCAAGTGGAGTGGATTATGATGTGCTCACCCCTG
ATGATATGGTAGTCATGGATCTTGAAGGAAATAAGATAGAGGGAAAATACAAGCCTTCGTCAGACACAGCAACACACTTA
GAGCTCTACAAAAAGTATCCGGATATTGGAGGAATTGTACATACGCACTCACCTGAGGCGGTTGCCTGGGCACAGGCCGG
CAGGGATATTCCGCTCTACGGCACCACTCACGCAGACTATTTCCTGGGCTCAATTCCATGTGCGAGAAATCTCACCACAG
AGGAAATCAACGAAGCCTATGAGAAAAACACAGGCCTTGTCATCATAGAGACATTTGAGAACAGAAAAATCAATCCTGTA
TACACACCGGCTGTGCTCTGTCAGAATCACGGACCGTTTGCCTGGGGAAAGGATGCGGCTGAGGCTGTGCACAACGCCGT
TGTCCTTGAGGAAGTGGCAAAGATGGCCAGACTCACAGAGTCAGTAAATCCTGACGTGAAGCCAGCCCCGGACAACATAA
AGGAGAAGCATTTCTACCGTAAGCATGGTGCTAACGCATACTATGGCCAGAACTGA

Upstream 100 bases:

>100_bases
GTACATAAATACATATAAGGCGGCAATTGAGGCAGAGCGTGCCATGGTAAAGGCGCTCCCGCTGTAATAGCAGTAAAAAA
TAATAAGAGAGGAACAAAAA

Downstream 100 bases:

>100_bases
TTTGTAACTGTTATATGTGGCCTAAGTGCCGGTTTCCGGGGTGCACATGCTCTCGTGTTCGCTACGCTGCATCACTAAGA
TACTGTACGAATTATGCTTT

Product: L-ribulose-5-phosphate 4-epimerase

Products: NA

Alternate protein names: Phosphoribulose isomerase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLEELKKQVYEANMELPRRGLITYTWGNVSGIDRETGYFVIKPSGVDYDVLTPDDMVVMDLEGNKIEGKYKPSSDTATHL
ELYKKYPDIGGIVHTHSPEAVAWAQAGRDIPLYGTTHADYFLGSIPCARNLTTEEINEAYEKNTGLVIIETFENRKINPV
YTPAVLCQNHGPFAWGKDAAEAVHNAVVLEEVAKMARLTESVNPDVKPAPDNIKEKHFYRKHGANAYYGQN

Sequences:

>Translated_231_residues
MLEELKKQVYEANMELPRRGLITYTWGNVSGIDRETGYFVIKPSGVDYDVLTPDDMVVMDLEGNKIEGKYKPSSDTATHL
ELYKKYPDIGGIVHTHSPEAVAWAQAGRDIPLYGTTHADYFLGSIPCARNLTTEEINEAYEKNTGLVIIETFENRKINPV
YTPAVLCQNHGPFAWGKDAAEAVHNAVVLEEVAKMARLTESVNPDVKPAPDNIKEKHFYRKHGANAYYGQN
>Mature_231_residues
MLEELKKQVYEANMELPRRGLITYTWGNVSGIDRETGYFVIKPSGVDYDVLTPDDMVVMDLEGNKIEGKYKPSSDTATHL
ELYKKYPDIGGIVHTHSPEAVAWAQAGRDIPLYGTTHADYFLGSIPCARNLTTEEINEAYEKNTGLVIIETFENRKINPV
YTPAVLCQNHGPFAWGKDAAEAVHNAVVLEEVAKMARLTESVNPDVKPAPDNIKEKHFYRKHGANAYYGQN

Specific function: Probable Pentulose-5-Phosphate-4-Epimerase. Probably Involved In A Metabolic Pathway With Sgah And Sgau. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790642, Length=229, Percent_Identity=62.4454148471616, Blast_Score=307, Evalue=3e-85,
Organism=Escherichia coli, GI1790008, Length=231, Percent_Identity=59.3073593073593, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1786247, Length=231, Percent_Identity=59.7402597402597, Blast_Score=289, Evalue=1e-79,
Organism=Escherichia coli, GI1789164, Length=210, Percent_Identity=30, Blast_Score=73, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322484, Length=231, Percent_Identity=26.8398268398268, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004661 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =5.1.3.4 [H]

Molecular weight: Translated: 25875; Mature: 25875

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEELKKQVYEANMELPRRGLITYTWGNVSGIDRETGYFVIKPSGVDYDVLTPDDMVVMD
CHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEECCCCEEEEE
LEGNKIEGKYKPSSDTATHLELYKKYPDIGGIVHTHSPEAVAWAQAGRDIPLYGTTHADY
CCCCEECCEECCCCCCHHHHHHHHHCCCCCCEEECCCCCEEEHHHCCCCCCEEECCCHHH
FLGSIPCARNLTTEEINEAYEKNTGLVIIETFENRKINPVYTPAVLCQNHGPFAWGKDAA
HHCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCEEECCCCCCCCCCHHH
EAVHNAVVLEEVAKMARLTESVNPDVKPAPDNIKEKHFYRKHGANAYYGQN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLEELKKQVYEANMELPRRGLITYTWGNVSGIDRETGYFVIKPSGVDYDVLTPDDMVVMD
CHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEECCCCEEEEE
LEGNKIEGKYKPSSDTATHLELYKKYPDIGGIVHTHSPEAVAWAQAGRDIPLYGTTHADY
CCCCEECCEECCCCCCHHHHHHHHHCCCCCCEEECCCCCEEEHHHCCCCCCEEECCCHHH
FLGSIPCARNLTTEEINEAYEKNTGLVIIETFENRKINPVYTPAVLCQNHGPFAWGKDAA
HHCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCEEECCCCCCCCCCHHH
EAVHNAVVLEEVAKMARLTESVNPDVKPAPDNIKEKHFYRKHGANAYYGQN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA