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The map label for this gene is dgkA [H]

Identifier: 238923074

GI number: 238923074

Start: 606810

End: 607178

Strand: Direct

Name: dgkA [H]

Synonym: EUBREC_0664

Alternate gene names: 238923074

Gene position: 606810-607178 (Clockwise)

Preceding gene: 238923070

Following gene: 238923075

Centisome position: 17.59

GC content: 46.34

Gene sequence:

>369_bases
ATGAAAAAAGCAAAGAAACCACCTCTGTACAAAAGCTTCGGATATGCCTTCGAGGGCATATTTACATGCATCAGAAATGA
GCGCAATATCAAGATACACTGCACTGTCGCGATACTTGTAGTGATAGCAGGAGCGGTACTTGGGATAACACCGACTGAGT
GGTGCATCTGCCTGACGCTGTTTGGATTGGTGATAGCCCTGGAGCTGGTCAACACTGCGATTGAGTCAGTTGTAGATTTG
GTAACGACAGAGCGAAAGCCGCTTGCCAAGACAGCTAAGGATACGGCAGCAGGAGCAGTGCTTGTTGCAGCAATAATGGC
TGCGATAGTTGGACTTATCATTTTTGTGCCAAGGATTGTTTCACTATAA

Upstream 100 bases:

>100_bases
TGCACAATCCTCTTTTATTTTGAACCAAAAAGTTATACAATAGTACCATAGTAAAAGGTATCAAAACTAATTCCAAAATT
AAATCACGAGAGGTATCAAC

Downstream 100 bases:

>100_bases
TAACAGGAAACGGAGGATTTTACCATGGAAAGACTTACAGACGGATTAAAGAAGATTATACTTGCAGGAATAGGAACAGT
GGCAGTGACCGCTGAGAAAT

Product: diacylglycerol kinase

Products: NA

Alternate protein names: UdpK [H]

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MKKAKKPPLYKSFGYAFEGIFTCIRNERNIKIHCTVAILVVIAGAVLGITPTEWCICLTLFGLVIALELVNTAIESVVDL
VTTERKPLAKTAKDTAAGAVLVAAIMAAIVGLIIFVPRIVSL

Sequences:

>Translated_122_residues
MKKAKKPPLYKSFGYAFEGIFTCIRNERNIKIHCTVAILVVIAGAVLGITPTEWCICLTLFGLVIALELVNTAIESVVDL
VTTERKPLAKTAKDTAAGAVLVAAIMAAIVGLIIFVPRIVSL
>Mature_122_residues
MKKAKKPPLYKSFGYAFEGIFTCIRNERNIKIHCTVAILVVIAGAVLGITPTEWCICLTLFGLVIALELVNTAIESVVDL
VTTERKPLAKTAKDTAAGAVLVAAIMAAIVGLIIFVPRIVSL

Specific function: Catalyzes the phosphorylation of undecaprenol, which is probably the primary physiological substrate. Is also able to phosphorylate diacylglycerol, albeit with very low efficiency. May play a role in adaptability to environmental stress conditions such as

COG id: COG0818

COG function: function code M; Diacylglycerol kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial diacylglycerol kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000829 [H]

Pfam domain/function: PF01219 DAGK_prokar [H]

EC number: =2.7.1.66 [H]

Molecular weight: Translated: 13055; Mature: 13055

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS01069 DAGK_PROKAR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAKKPPLYKSFGYAFEGIFTCIRNERNIKIHCTVAILVVIAGAVLGITPTEWCICLTL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FGLVIALELVNTAIESVVDLVTTERKPLAKTAKDTAAGAVLVAAIMAAIVGLIIFVPRIV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SL
CC
>Mature Secondary Structure
MKKAKKPPLYKSFGYAFEGIFTCIRNERNIKIHCTVAILVVIAGAVLGITPTEWCICLTL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FGLVIALELVNTAIESVVDLVTTERKPLAKTAKDTAAGAVLVAAIMAAIVGLIIFVPRIV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8407794; 9422608; 12397186 [H]