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The map label for this gene is mtnU [H]

Identifier: 238923044

GI number: 238923044

Start: 577932

End: 578774

Strand: Direct

Name: mtnU [H]

Synonym: EUBREC_0634

Alternate gene names: 238923044

Gene position: 577932-578774 (Clockwise)

Preceding gene: 238923043

Following gene: 238923045

Centisome position: 16.75

GC content: 34.99

Gene sequence:

>843_bases
ATGTTCAAGGTTGCTATACTACAAAAACGTTCTATTAATGAACAAATAGATAAGAATATTGAAACTATCATTATGGCAAT
GGAAGAGGCTTCGGAAAAACATGCAGATATTCTATTGTTGCCAGAATGTTTTATTACAGGATATGATTTGCCTATGTCAT
ATGAAAAAAGCATTGCAGATAATGATATAAGAATTGCCCAAATATGTGAGAATGCTAAAAAATATAAAATAGGCGTAGTA
CTTACTGCATTTACAAAAGGTAGTAAGCAACCACAGAACTCAGCCTTTGTTATCAATAAGTCGGGAAATATATTGATGAA
ATACTCTAAGGTGCATACCTGTGATTTCGCAGATGAAAGAGATGTTGAATCAGGGAAAGAATTTAAGGTGTGTGATTTTG
AAGGAATACAATTAGGTATTATGATTTGTTATGACAGAGAATACCCGGAAAGTGCAAGAATACTTATGTTAAAAGGTGCA
GAAGTTATTCTTGTACCAAATGATTGTGGTTCCATGCAAGCAAGAATCAGGGCACTTTCGACAAGAGCTTATGAAAATAT
GGTTGCAGTCGCTATGGCAAATCCGAATGGAGATAATGCTGGATGTTCCTGCGCATATAGTCCAATTTGCTGGGATAGAA
ATGGAAAATGTGTTGATAACACAGTTTTGCTGGCTGATGATAAAACTGAGGGGATTTTTTATGCGGAGTTTGATATGGAA
GCTATTAGAGAATACAGGAATCGGGAAATGTTAGGAAACACATTTCGTAAGGTAGAATCATATAGTCGGTTGTTAAGTAA
AGAAATCAAGGAACCATTTATAAGGGATGGCCAGAATAGATAA

Upstream 100 bases:

>100_bases
ATTTGGAAGTTTGTGGACTGTAATGGACGAGAGTGAAAAAGCCGATATTGAAGTTAATAACTTATCTGACATTTTGAATT
ATCTATAGGAGGGAAAGTGA

Downstream 100 bases:

>100_bases
ATCAGAAGTAACAAGAGGAATATTTTATCGAGGTTCAGATGTAGAATGTCAATTGCTCTATGTAATGGGTGATATGGAGG
CGGATATCAGAACACATCAT

Product: amidohydrolase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MFKVAILQKRSINEQIDKNIETIIMAMEEASEKHADILLLPECFITGYDLPMSYEKSIADNDIRIAQICENAKKYKIGVV
LTAFTKGSKQPQNSAFVINKSGNILMKYSKVHTCDFADERDVESGKEFKVCDFEGIQLGIMICYDREYPESARILMLKGA
EVILVPNDCGSMQARIRALSTRAYENMVAVAMANPNGDNAGCSCAYSPICWDRNGKCVDNTVLLADDKTEGIFYAEFDME
AIREYRNREMLGNTFRKVESYSRLLSKEIKEPFIRDGQNR

Sequences:

>Translated_280_residues
MFKVAILQKRSINEQIDKNIETIIMAMEEASEKHADILLLPECFITGYDLPMSYEKSIADNDIRIAQICENAKKYKIGVV
LTAFTKGSKQPQNSAFVINKSGNILMKYSKVHTCDFADERDVESGKEFKVCDFEGIQLGIMICYDREYPESARILMLKGA
EVILVPNDCGSMQARIRALSTRAYENMVAVAMANPNGDNAGCSCAYSPICWDRNGKCVDNTVLLADDKTEGIFYAEFDME
AIREYRNREMLGNTFRKVESYSRLLSKEIKEPFIRDGQNR
>Mature_280_residues
MFKVAILQKRSINEQIDKNIETIIMAMEEASEKHADILLLPECFITGYDLPMSYEKSIADNDIRIAQICENAKKYKIGVV
LTAFTKGSKQPQNSAFVINKSGNILMKYSKVHTCDFADERDVESGKEFKVCDFEGIQLGIMICYDREYPESARILMLKGA
EVILVPNDCGSMQARIRALSTRAYENMVAVAMANPNGDNAGCSCAYSPICWDRNGKCVDNTVLLADDKTEGIFYAEFDME
AIREYRNREMLGNTFRKVESYSRLLSKEIKEPFIRDGQNR

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=286, Percent_Identity=25.8741258741259, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323383, Length=282, Percent_Identity=26.9503546099291, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355835, Length=272, Percent_Identity=23.8970588235294, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31736; Mature: 31736

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKVAILQKRSINEQIDKNIETIIMAMEEASEKHADILLLPECFITGYDLPMSYEKSIAD
CEEEEEEHHHCHHHHHHCCHHHHHHHHHHHCCCCCCEEEECHHHEECCCCCCCHHHCCCC
NDIRIAQICENAKKYKIGVVLTAFTKGSKQPQNSAFVINKSGNILMKYSKVHTCDFADER
CCCHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCCCC
DVESGKEFKVCDFEGIQLGIMICYDREYPESARILMLKGAEVILVPNDCGSMQARIRALS
CCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCEEEEEECCCCHHHHHHHHHH
TRAYENMVAVAMANPNGDNAGCSCAYSPICWDRNGKCVDNTVLLADDKTEGIFYAEFDME
HHHHHCEEEEEEECCCCCCCCCEEECCCEEECCCCCEECCEEEEECCCCCCEEEEECCHH
AIREYRNREMLGNTFRKVESYSRLLSKEIKEPFIRDGQNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCC
>Mature Secondary Structure
MFKVAILQKRSINEQIDKNIETIIMAMEEASEKHADILLLPECFITGYDLPMSYEKSIAD
CEEEEEEHHHCHHHHHHCCHHHHHHHHHHHCCCCCCEEEECHHHEECCCCCCCHHHCCCC
NDIRIAQICENAKKYKIGVVLTAFTKGSKQPQNSAFVINKSGNILMKYSKVHTCDFADER
CCCHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCCCC
DVESGKEFKVCDFEGIQLGIMICYDREYPESARILMLKGAEVILVPNDCGSMQARIRALS
CCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCEEEEEECCCCHHHHHHHHHH
TRAYENMVAVAMANPNGDNAGCSCAYSPICWDRNGKCVDNTVLLADDKTEGIFYAEFDME
HHHHHCEEEEEEECCCCCCCCCEEECCCEEECCCCCEECCEEEEECCCCCCEEEEECCHH
AIREYRNREMLGNTFRKVESYSRLLSKEIKEPFIRDGQNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]