Click here to switch to the map view.

The map label for this gene is mglB [H]

Identifier: 238922896

GI number: 238922896

Start: 442756

End: 443772

Strand: Direct

Name: mglB [H]

Synonym: EUBREC_0484

Alternate gene names: 238922896

Gene position: 442756-443772 (Clockwise)

Preceding gene: 238922895

Following gene: 238922898

Centisome position: 12.83

GC content: 45.72

Gene sequence:

>1017_bases
ATGATGATACTGTGTTTTGCACTGATATTGTCATTTGTCTCGTGCAGCAACACAAGAGTTGACGAGAAAAAACAGATATA
TATAGGTGTGACCTGTTATGACCAGAAGGATACATTTATCGGGGAGCTGATAGAAACTTTCAAAAAGGAGTGCGCAAGTC
TTGATACAGACAAATACGATATCAGCATGACAATCATGGATGCTGCAGGCTCACAGCGTGCACAGGATGATCAGGTGCAG
GAGATGATAGAGGACGGCTGCAATGTGCTGTGTATTAATCTGGCAGACAGAACAGATTTGTCGCATATTATAAATGCTGC
AATGGAGAAGGACATCCCGATTATTTTCTTTAACAGGGAGCCGGTTGATGAGGATTTAAATCGCTGGGATAAGCTGTACT
ATGTCGGGGCCAAGGCAAAGCAGTCAGGTCAGATGCAGGGGGAACTCATCGCCGATTATATAAAGAATAATCCGGGTGTG
GATAAAAACGGTGATGGCAGGATACAGTACGTCATCCTGGAGGGAGAGATGGGACATCAGGATGCCATCGTCAGGACAGA
GAGTGTGACAGAGAGCATGAAGAATAACGGTCTTCAGATAGAAAAGCTGAGCTGTCAGATAGCAAACTGGAATCGTGCTC
AGGCGCAGAACCGTATGACACAGCTTATAGGTCAGTATAAAAACAGCATAGAGCTGGTTATTGCAAACAACGATGCAATG
GCACTCGGAGCGATAGACGCATACGAAAAGCTTGGTGTGACGGAGTCGAATGTACCTGCATTTTTTGGAGTGGACGGCAC
AGACGATGGGCTTGAAGCAGTGCAGCAGTCGAAGCTTGCGGCAACAGTCTACAATGACAAGGAGGGACAGGCAATGGCTA
TGGCTCAGCTTGCTTATCTGGCAGCCACCGGGGGCAGCATGAAAAACATAAAGTTTGAGGATAAAAAGTATGTTTATCTG
CCGTATGAGAAGGTGACCCCTGACAATGTAAATGAATTTGTGAAGGATGAACAGTGA

Upstream 100 bases:

>100_bases
TTACCAGAAAAAATCTGTTTGATGAAGAAAACAAGAAGCTTTTGTATGCAATCAGCCAGTAGTGGGGGAACAATAAATGA
GAAGCAGAATAAGAAATACC

Downstream 100 bases:

>100_bases
GCTTATTTATGCTCGTTCCTCCACTCCCTCGGAGCCACTCCGTAGATATTTTTAAAGGCGCGTGAGAAATGAAGCTGATT
TTCGTATCCAACGGCAGAAC

Product: D-galactose-binding periplasmic protein precursor

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: GBP; D-galactose/ D-glucose-binding protein; GGBP [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MMILCFALILSFVSCSNTRVDEKKQIYIGVTCYDQKDTFIGELIETFKKECASLDTDKYDISMTIMDAAGSQRAQDDQVQ
EMIEDGCNVLCINLADRTDLSHIINAAMEKDIPIIFFNREPVDEDLNRWDKLYYVGAKAKQSGQMQGELIADYIKNNPGV
DKNGDGRIQYVILEGEMGHQDAIVRTESVTESMKNNGLQIEKLSCQIANWNRAQAQNRMTQLIGQYKNSIELVIANNDAM
ALGAIDAYEKLGVTESNVPAFFGVDGTDDGLEAVQQSKLAATVYNDKEGQAMAMAQLAYLAATGGSMKNIKFEDKKYVYL
PYEKVTPDNVNEFVKDEQ

Sequences:

>Translated_338_residues
MMILCFALILSFVSCSNTRVDEKKQIYIGVTCYDQKDTFIGELIETFKKECASLDTDKYDISMTIMDAAGSQRAQDDQVQ
EMIEDGCNVLCINLADRTDLSHIINAAMEKDIPIIFFNREPVDEDLNRWDKLYYVGAKAKQSGQMQGELIADYIKNNPGV
DKNGDGRIQYVILEGEMGHQDAIVRTESVTESMKNNGLQIEKLSCQIANWNRAQAQNRMTQLIGQYKNSIELVIANNDAM
ALGAIDAYEKLGVTESNVPAFFGVDGTDDGLEAVQQSKLAATVYNDKEGQAMAMAQLAYLAATGGSMKNIKFEDKKYVYL
PYEKVTPDNVNEFVKDEQ
>Mature_338_residues
MMILCFALILSFVSCSNTRVDEKKQIYIGVTCYDQKDTFIGELIETFKKECASLDTDKYDISMTIMDAAGSQRAQDDQVQ
EMIEDGCNVLCINLADRTDLSHIINAAMEKDIPIIFFNREPVDEDLNRWDKLYYVGAKAKQSGQMQGELIADYIKNNPGV
DKNGDGRIQYVILEGEMGHQDAIVRTESVTESMKNNGLQIEKLSCQIANWNRAQAQNRMTQLIGQYKNSIELVIANNDAM
ALGAIDAYEKLGVTESNVPAFFGVDGTDDGLEAVQQSKLAATVYNDKEGQAMAMAQLAYLAATGGSMKNIKFEDKKYVYL
PYEKVTPDNVNEFVKDEQ

Specific function: This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788473, Length=311, Percent_Identity=38.5852090032154, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1790192, Length=235, Percent_Identity=26.3829787234043, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: 4720 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1320 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37760; Mature: 37760

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILCFALILSFVSCSNTRVDEKKQIYIGVTCYDQKDTFIGELIETFKKECASLDTDKYD
CHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEE
ISMTIMDAAGSQRAQDDQVQEMIEDGCNVLCINLADRTDLSHIINAAMEKDIPIIFFNRE
EEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCC
PVDEDLNRWDKLYYVGAKAKQSGQMQGELIADYIKNNPGVDKNGDGRIQYVILEGEMGHQ
CCHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCC
DAIVRTESVTESMKNNGLQIEKLSCQIANWNRAQAQNRMTQLIGQYKNSIELVIANNDAM
CCEEEHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEE
ALGAIDAYEKLGVTESNVPAFFGVDGTDDGLEAVQQSKLAATVYNDKEGQAMAMAQLAYL
EEECHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHH
AATGGSMKNIKFEDKKYVYLPYEKVTPDNVNEFVKDEQ
HHCCCCCCCEEECCCEEEEECCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MMILCFALILSFVSCSNTRVDEKKQIYIGVTCYDQKDTFIGELIETFKKECASLDTDKYD
CHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEE
ISMTIMDAAGSQRAQDDQVQEMIEDGCNVLCINLADRTDLSHIINAAMEKDIPIIFFNRE
EEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCC
PVDEDLNRWDKLYYVGAKAKQSGQMQGELIADYIKNNPGVDKNGDGRIQYVILEGEMGHQ
CCHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCC
DAIVRTESVTESMKNNGLQIEKLSCQIANWNRAQAQNRMTQLIGQYKNSIELVIANNDAM
CCEEEHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEE
ALGAIDAYEKLGVTESNVPAFFGVDGTDDGLEAVQQSKLAATVYNDKEGQAMAMAQLAYL
EEECHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHH
AATGGSMKNIKFEDKKYVYLPYEKVTPDNVNEFVKDEQ
HHCCCCCCCEEECCCEEEEECCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA