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The map label for this gene is yesM [H]

Identifier: 238922894

GI number: 238922894

Start: 439872

End: 441665

Strand: Direct

Name: yesM [H]

Synonym: EUBREC_0482

Alternate gene names: 238922894

Gene position: 439872-441665 (Clockwise)

Preceding gene: 238922893

Following gene: 238922895

Centisome position: 12.75

GC content: 41.64

Gene sequence:

>1794_bases
ATGAGAAGAATAAGGTATAAATCAGGCAATATACAATCCATAATAATGCTCTCATTCTCACTGCTGTCGTTTGCAATAAT
GCTTGTCACAGTTGTGGTGATGTATATAAAATTTGCCGATGCATCGCAGGACAGTATCATAGAGAGCAATCATAAGGTGA
TGGACCAGACAATAGACAGTGTGGAAAGCTATCTGGTCAATATGAGGCAGGTTTCGGATGCGGCGTATTATAATGTAATA
AAGGAGAATGATATTTTAAAGCAGTCTGACAGCATACACGATGGCATGAGCCTGCTCTATGAGTCAAACAAGGAATATCT
GCGCAGTATTGCCTTGTATAATCAGTATGGAAGCCTTATAGCTGCAGAGCCTGTTGTGTCCCAGAAGGAGGACCCGGATG
TGACAAAACAGGACTGGTTCATAGAAGCTATGGAGCGCATGGAAAATATACATTTTTCAACACCTCATGTACAGAATCTG
TTTGACGATGGTTCCATGAGATATCATCTGGTCATATCATCAAGCCGTGCCGTGGAGCTGACCTCAGGTTCAGAATCACA
GATGGGTGTGATGCTTGTGGACATGGATTATTCGAGTGTATCAAGGATGCTTGAGAGGATAAATACATCGGGAAAAGGAC
AGTATTATTATCTGTGTGATGCAAAGGGCAATATTATTTACCATCCGCATCAGATACAGTTTGATGGAGATGTTCCGGAA
AACAGCGATGTTGCGGCAAAGTCGCAAAACAGTATATATGATGATTATCTGAATGGAGTGCATCGTAAGATTATGGTAGA
TACAATCAGCTACACAGGCTGGAAGCTTGTATGTGTGATGCCATACTCCATCTTTACCAATAAGATGGCGGATGTGAAGC
AGTTTGTTTTTGTTATAATGATTATTATGGCTATGATGTTTGTGTGGATAAACAGAGTGATAGCTATACGTATTTCAAAG
CCGATAATGAAGCTGGATGATTCTGTGAAAAGGTATGAGAATGGCAATGAAGCAGATATTTATGTAGGTGGTTCCTCAGA
GATACGGCATCTGGGATACTCTATACGTAATTCATATAAGCAGAACAATGAGCTCATGAAAAAGATCGTATGGGAGCAGA
ACGAGAGACGAAAGAGCGAGCTTGATGTGCTTCAAAGCCAGATTAATCCGCACTTTTTGTATAATACTCTTGACTCCATC
ACATGGATGATTGAAGGAGGCAAAAACGAGGAGGCCTCGTTTATGATTACGCAGCTTGCAAAACTTTTCCGTATCAGTCT
GTCGAAGGGACATACCATAATACCTGTACGAGATGAGCTTTTGCACGCAAAAAGCTACATGAATATTCAGAAGGTGCGCT
ATAAGAACAAATTTGAGGTGAGCTTTGAGGTAGACGAGGAAATAATGGACTACTGTGCGGTGAAGCTGGTGCTTCAGCCG
ATTTTGGAAAACGCACTAAATTACGGAATCAGAGAGCTGGACGATTTCGGAGAGATAGTAGTCGGAGGCCAAAAAGTGGG
AGAGGATATCATCATAACGGTATCAGACAACGGAATGGGCATTCCGGAGAATGAAATTCCGTTTTTGCTGACAAATACGG
ACAGGGTTCACAAGAAGGGCTCGGGAGTAGGGCTTGTCAATGTAAATAACAGGATAAAGATACTGTTTGGAGAGCGCTAT
GGCCTGCATATAGAAAGTGAGCTTGATGAGGGAACAGTTGTGACAATCAAAATCCCGGCAATTGTCTATTCAGAGGAAAA
CAGACTTCAATTTGAGGAGCATCATATAGTATGA

Upstream 100 bases:

>100_bases
TATGTCATAGCCCAGAATGTAGGCTATGCGGATCCGAACTATTTCAGTTATGTTTTTAAGAGAAAGTATGGGGTTTCCCC
ATCCAGGTACAGGACAGAGT

Downstream 100 bases:

>100_bases
AGCAAGTACAATTCCCTTGCTGCATGGGAGGTGTGAGAGTGACAGTGAAAAATAAATGGACAAATATGAGCAAGAATAAG
AGAAACTTCATCATAACAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MRRIRYKSGNIQSIIMLSFSLLSFAIMLVTVVVMYIKFADASQDSIIESNHKVMDQTIDSVESYLVNMRQVSDAAYYNVI
KENDILKQSDSIHDGMSLLYESNKEYLRSIALYNQYGSLIAAEPVVSQKEDPDVTKQDWFIEAMERMENIHFSTPHVQNL
FDDGSMRYHLVISSSRAVELTSGSESQMGVMLVDMDYSSVSRMLERINTSGKGQYYYLCDAKGNIIYHPHQIQFDGDVPE
NSDVAAKSQNSIYDDYLNGVHRKIMVDTISYTGWKLVCVMPYSIFTNKMADVKQFVFVIMIIMAMMFVWINRVIAIRISK
PIMKLDDSVKRYENGNEADIYVGGSSEIRHLGYSIRNSYKQNNELMKKIVWEQNERRKSELDVLQSQINPHFLYNTLDSI
TWMIEGGKNEEASFMITQLAKLFRISLSKGHTIIPVRDELLHAKSYMNIQKVRYKNKFEVSFEVDEEIMDYCAVKLVLQP
ILENALNYGIRELDDFGEIVVGGQKVGEDIIITVSDNGMGIPENEIPFLLTNTDRVHKKGSGVGLVNVNNRIKILFGERY
GLHIESELDEGTVVTIKIPAIVYSEENRLQFEEHHIV

Sequences:

>Translated_597_residues
MRRIRYKSGNIQSIIMLSFSLLSFAIMLVTVVVMYIKFADASQDSIIESNHKVMDQTIDSVESYLVNMRQVSDAAYYNVI
KENDILKQSDSIHDGMSLLYESNKEYLRSIALYNQYGSLIAAEPVVSQKEDPDVTKQDWFIEAMERMENIHFSTPHVQNL
FDDGSMRYHLVISSSRAVELTSGSESQMGVMLVDMDYSSVSRMLERINTSGKGQYYYLCDAKGNIIYHPHQIQFDGDVPE
NSDVAAKSQNSIYDDYLNGVHRKIMVDTISYTGWKLVCVMPYSIFTNKMADVKQFVFVIMIIMAMMFVWINRVIAIRISK
PIMKLDDSVKRYENGNEADIYVGGSSEIRHLGYSIRNSYKQNNELMKKIVWEQNERRKSELDVLQSQINPHFLYNTLDSI
TWMIEGGKNEEASFMITQLAKLFRISLSKGHTIIPVRDELLHAKSYMNIQKVRYKNKFEVSFEVDEEIMDYCAVKLVLQP
ILENALNYGIRELDDFGEIVVGGQKVGEDIIITVSDNGMGIPENEIPFLLTNTDRVHKKGSGVGLVNVNNRIKILFGERY
GLHIESELDEGTVVTIKIPAIVYSEENRLQFEEHHIV
>Mature_597_residues
MRRIRYKSGNIQSIIMLSFSLLSFAIMLVTVVVMYIKFADASQDSIIESNHKVMDQTIDSVESYLVNMRQVSDAAYYNVI
KENDILKQSDSIHDGMSLLYESNKEYLRSIALYNQYGSLIAAEPVVSQKEDPDVTKQDWFIEAMERMENIHFSTPHVQNL
FDDGSMRYHLVISSSRAVELTSGSESQMGVMLVDMDYSSVSRMLERINTSGKGQYYYLCDAKGNIIYHPHQIQFDGDVPE
NSDVAAKSQNSIYDDYLNGVHRKIMVDTISYTGWKLVCVMPYSIFTNKMADVKQFVFVIMIIMAMMFVWINRVIAIRISK
PIMKLDDSVKRYENGNEADIYVGGSSEIRHLGYSIRNSYKQNNELMKKIVWEQNERRKSELDVLQSQINPHFLYNTLDSI
TWMIEGGKNEEASFMITQLAKLFRISLSKGHTIIPVRDELLHAKSYMNIQKVRYKNKFEVSFEVDEEIMDYCAVKLVLQP
ILENALNYGIRELDDFGEIVVGGQKVGEDIIITVSDNGMGIPENEIPFLLTNTDRVHKKGSGVGLVNVNNRIKILFGERY
GLHIESELDEGTVVTIKIPAIVYSEENRLQFEEHHIV

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=221, Percent_Identity=30.316742081448, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788723, Length=203, Percent_Identity=34.4827586206897, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68488; Mature: 68488

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIRYKSGNIQSIIMLSFSLLSFAIMLVTVVVMYIKFADASQDSIIESNHKVMDQTIDS
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHH
VESYLVNMRQVSDAAYYNVIKENDILKQSDSIHDGMSLLYESNKEYLRSIALYNQYGSLI
HHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCEE
AAEPVVSQKEDPDVTKQDWFIEAMERMENIHFSTPHVQNLFDDGSMRYHLVISSSRAVEL
EECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEECCCEEEE
TSGSESQMGVMLVDMDYSSVSRMLERINTSGKGQYYYLCDAKGNIIYHPHQIQFDGDVPE
ECCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEECCEEEEECCCCCC
NSDVAAKSQNSIYDDYLNGVHRKIMVDTISYTGWKLVCVMPYSIFTNKMADVKQFVFVIM
CCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHH
IIMAMMFVWINRVIAIRISKPIMKLDDSVKRYENGNEADIYVGGSSEIRHLGYSIRNSYK
HHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
QNNELMKKIVWEQNERRKSELDVLQSQINPHFLYNTLDSITWMIEGGKNEEASFMITQLA
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCHHHHHHHHH
KLFRISLSKGHTIIPVRDELLHAKSYMNIQKVRYKNKFEVSFEVDEEIMDYCAVKLVLQP
HHHHHHHCCCCEEEEEHHHHHHHHHHCCHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHH
ILENALNYGIRELDDFGEIVVGGQKVGEDIIITVSDNGMGIPENEIPFLLTNTDRVHKKG
HHHHHHHCCHHHHHCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCEEEECCHHHHCCC
SGVGLVNVNNRIKILFGERYGLHIESELDEGTVVTIKIPAIVYSEENRLQFEEHHIV
CCEEEEEECCEEEEEEECCCCEEEECCCCCCEEEEEEEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure
MRRIRYKSGNIQSIIMLSFSLLSFAIMLVTVVVMYIKFADASQDSIIESNHKVMDQTIDS
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHH
VESYLVNMRQVSDAAYYNVIKENDILKQSDSIHDGMSLLYESNKEYLRSIALYNQYGSLI
HHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCEE
AAEPVVSQKEDPDVTKQDWFIEAMERMENIHFSTPHVQNLFDDGSMRYHLVISSSRAVEL
EECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEECCCEEEE
TSGSESQMGVMLVDMDYSSVSRMLERINTSGKGQYYYLCDAKGNIIYHPHQIQFDGDVPE
ECCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEECCEEEEECCCCCC
NSDVAAKSQNSIYDDYLNGVHRKIMVDTISYTGWKLVCVMPYSIFTNKMADVKQFVFVIM
CCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHH
IIMAMMFVWINRVIAIRISKPIMKLDDSVKRYENGNEADIYVGGSSEIRHLGYSIRNSYK
HHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
QNNELMKKIVWEQNERRKSELDVLQSQINPHFLYNTLDSITWMIEGGKNEEASFMITQLA
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCHHHHHHHHH
KLFRISLSKGHTIIPVRDELLHAKSYMNIQKVRYKNKFEVSFEVDEEIMDYCAVKLVLQP
HHHHHHHCCCCEEEEEHHHHHHHHHHCCHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHH
ILENALNYGIRELDDFGEIVVGGQKVGEDIIITVSDNGMGIPENEIPFLLTNTDRVHKKG
HHHHHHHCCHHHHHCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCEEEECCHHHHCCC
SGVGLVNVNNRIKILFGERYGLHIESELDEGTVVTIKIPAIVYSEENRLQFEEHHIV
CCEEEEEECCEEEEEEECCCCEEEECCCCCCEEEEEEEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]