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The map label for this gene is add [H]

Identifier: 238922806

GI number: 238922806

Start: 359744

End: 360691

Strand: Direct

Name: add [H]

Synonym: EUBREC_0394

Alternate gene names: 238922806

Gene position: 359744-360691 (Clockwise)

Preceding gene: 238922805

Following gene: 238922809

Centisome position: 10.43

GC content: 34.07

Gene sequence:

>948_bases
GTGAATGGTTTTACAGATGCATTGGAACAAAGAAATCTGGAAGAGTTAAGAAAGTATCCTAAGGCAGATTTGCACAATCA
TTTTGTGCTTGGCGGAAATAGACGGTTCATATATCAGGAAACTCGAAAAAAAATTGAGCCATTAGCTAATCCTTTGTCAT
CAATGGATGAGATGAATCAATGGAGTCAAAAATATATTAGTCAAGACTTTAATAGCACTGCGATGAGAAAATTTTTGATC
AGAGCAACATTTCAACAAGCCAGAGAGGATGGAGTAACTGTGCTTGAAATTGGTGAAGATGTGTGGGGCTTAAACGAATT
TTTTAATAATGATATTGATGAGTTGGTTAATGCTTTTACAAGTGCTCAAAAAGAAATCGCTCCCGATATAGAATTAAGGC
TTCAAATTGGATTATCAAGACATTGTTCGATCAGTTATTTAGAAGATTGTTTATCATATTTTTGGGGAAATAAGAATTTT
TATTCTATTGATTTGTACGGTGATGAATTAGCACAACCTATCGAAAATTTTAAAGGAATTTATCGGCGTGCAAAAAAAGA
AGGATTAAGGCTAAAAGCACACGTCGGAGAATGGGGGACTGCTAAAGACGTAAGAACAGCCGTAGAAGAATTAGAACTTG
ATGAGGTTCAGCATGGGATAGCGGCAGTCAGTGATGAATCAGTAATCCGTTTTTTGGCAGATAATAAAATTAGATTAAAT
ATTACACCAACAAGTAATATTTTACTTGGAAGGGTAGCAGATATGTCTATGCATCCGATTGGAAAACTGTATCGTAGTGG
TGTTGATGTTACTATAAATTCCGATGATGTATTAATATTTGATTCAGATGTATCCAAAGAATATCTACGGCTTTATGAGT
TTCAGTGCTTAACAGCAGAAGAATTAGAAAACATAAGAAAAAATGGACTAAAACCTATAATTATATAG

Upstream 100 bases:

>100_bases
TCATGCCCTGTTTTTTATGGTAGTCGGGATGAGGGAAAAGTGCTACAATTAAAAGGAAAAAATTGTAGAGAAAATTAAAA
ACATAGGAGGAAACGTATTT

Downstream 100 bases:

>100_bases
ACAAATTGAAATTGCAGACTTCCTTATTGATCATATCTAAACATGGTGCTAGCACCATGTAATAAAGGTAATTAAGGAGA
AAATCGGTATTTTTGGAGTG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNGFTDALEQRNLEELRKYPKADLHNHFVLGGNRRFIYQETRKKIEPLANPLSSMDEMNQWSQKYISQDFNSTAMRKFLI
RATFQQAREDGVTVLEIGEDVWGLNEFFNNDIDELVNAFTSAQKEIAPDIELRLQIGLSRHCSISYLEDCLSYFWGNKNF
YSIDLYGDELAQPIENFKGIYRRAKKEGLRLKAHVGEWGTAKDVRTAVEELELDEVQHGIAAVSDESVIRFLADNKIRLN
ITPTSNILLGRVADMSMHPIGKLYRSGVDVTINSDDVLIFDSDVSKEYLRLYEFQCLTAEELENIRKNGLKPIII

Sequences:

>Translated_315_residues
MNGFTDALEQRNLEELRKYPKADLHNHFVLGGNRRFIYQETRKKIEPLANPLSSMDEMNQWSQKYISQDFNSTAMRKFLI
RATFQQAREDGVTVLEIGEDVWGLNEFFNNDIDELVNAFTSAQKEIAPDIELRLQIGLSRHCSISYLEDCLSYFWGNKNF
YSIDLYGDELAQPIENFKGIYRRAKKEGLRLKAHVGEWGTAKDVRTAVEELELDEVQHGIAAVSDESVIRFLADNKIRLN
ITPTSNILLGRVADMSMHPIGKLYRSGVDVTINSDDVLIFDSDVSKEYLRLYEFQCLTAEELENIRKNGLKPIII
>Mature_315_residues
MNGFTDALEQRNLEELRKYPKADLHNHFVLGGNRRFIYQETRKKIEPLANPLSSMDEMNQWSQKYISQDFNSTAMRKFLI
RATFQQAREDGVTVLEIGEDVWGLNEFFNNDIDELVNAFTSAQKEIAPDIELRLQIGLSRHCSISYLEDCLSYFWGNKNF
YSIDLYGDELAQPIENFKGIYRRAKKEGLRLKAHVGEWGTAKDVRTAVEELELDEVQHGIAAVSDESVIRFLADNKIRLN
ITPTSNILLGRVADMSMHPIGKLYRSGVDVTINSDDVLIFDSDVSKEYLRLYEFQCLTAEELENIRKNGLKPIII

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=172, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787910, Length=175, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36254; Mature: 36254

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFTDALEQRNLEELRKYPKADLHNHFVLGGNRRFIYQETRKKIEPLANPLSSMDEMNQ
CCCHHHHHHHCCHHHHHCCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
WSQKYISQDFNSTAMRKFLIRATFQQAREDGVTVLEIGEDVWGLNEFFNNDIDELVNAFT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHHHH
SAQKEIAPDIELRLQIGLSRHCSISYLEDCLSYFWGNKNFYSIDLYGDELAQPIENFKGI
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHH
YRRAKKEGLRLKAHVGEWGTAKDVRTAVEELELDEVQHGIAAVSDESVIRFLADNKIRLN
HHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEE
ITPTSNILLGRVADMSMHPIGKLYRSGVDVTINSDDVLIFDSDVSKEYLRLYEFQCLTAE
ECCCCCCHHHHHHCCCCCHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHCCCHH
ELENIRKNGLKPIII
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MNGFTDALEQRNLEELRKYPKADLHNHFVLGGNRRFIYQETRKKIEPLANPLSSMDEMNQ
CCCHHHHHHHCCHHHHHCCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
WSQKYISQDFNSTAMRKFLIRATFQQAREDGVTVLEIGEDVWGLNEFFNNDIDELVNAFT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHHHH
SAQKEIAPDIELRLQIGLSRHCSISYLEDCLSYFWGNKNFYSIDLYGDELAQPIENFKGI
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHH
YRRAKKEGLRLKAHVGEWGTAKDVRTAVEELELDEVQHGIAAVSDESVIRFLADNKIRLN
HHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEE
ITPTSNILLGRVADMSMHPIGKLYRSGVDVTINSDDVLIFDSDVSKEYLRLYEFQCLTAE
ECCCCCCHHHHHHCCCCCHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHCCCHH
ELENIRKNGLKPIII
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]