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The map label for this gene is cymR [H]

Identifier: 238922731

GI number: 238922731

Start: 285014

End: 285448

Strand: Direct

Name: cymR [H]

Synonym: EUBREC_0307

Alternate gene names: 238922731

Gene position: 285014-285448 (Clockwise)

Preceding gene: 238922730

Following gene: 238922732

Centisome position: 8.26

GC content: 45.06

Gene sequence:

>435_bases
ATGAAAATTTCAACAAAAGGACGTTATGCTCTTCGCCTCATGATGGATCTTGCAGAGAACAACACTGGTTCACCCATCAG
CCTGAAGGATGTAGCGAAGAGACAGGATATTTCAGATAAATATCTTGAACAGATTATATCCATTTTAAACAAGGCGGGCT
ACGTCAGAAGTGTCAGAGGCGCCCAGGGTGGATACATGCTGAAGATGGAACCGCAGAACTACACAGTCGGCATGATTCTC
AGACAGACTGAGGGCAGCCTTGCGCCGGTAGCATGTATAGAGGATGACGAGATAGTCTGTGACAGACAGCAGCAGTGCGT
CACATCTATTGTGTACAAGAAGATCAATGATGCAATCTCAGGTGTGGTTGACAATATCACCTTGCAGGATCTGGTAGACT
GGCAGAACGAGAAGAATGGAAATTATGTCATATAA

Upstream 100 bases:

>100_bases
ATTAAGCCTGACAAATGAAATGATTTCTGTTTTTCGGCTTGACAAAGGCGATTTCTGAATGTATAGTAAAGCAGTAGGAA
ATGAAACAGAGGTGCTATAA

Downstream 100 bases:

>100_bases
AGAAAGAAGGTTATCATAGATGAGCAGATTAATTTATTTGGATAATGCGGCAACCACACAGGTATATCCGGAGGTTGTGG
ATGCAATGCTTCCTTACTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKISTKGRYALRLMMDLAENNTGSPISLKDVAKRQDISDKYLEQIISILNKAGYVRSVRGAQGGYMLKMEPQNYTVGMIL
RQTEGSLAPVACIEDDEIVCDRQQQCVTSIVYKKINDAISGVVDNITLQDLVDWQNEKNGNYVI

Sequences:

>Translated_144_residues
MKISTKGRYALRLMMDLAENNTGSPISLKDVAKRQDISDKYLEQIISILNKAGYVRSVRGAQGGYMLKMEPQNYTVGMIL
RQTEGSLAPVACIEDDEIVCDRQQQCVTSIVYKKINDAISGVVDNITLQDLVDWQNEKNGNYVI
>Mature_144_residues
MKISTKGRYALRLMMDLAENNTGSPISLKDVAKRQDISDKYLEQIISILNKAGYVRSVRGAQGGYMLKMEPQNYTVGMIL
RQTEGSLAPVACIEDDEIVCDRQQQCVTSIVYKKINDAISGVVDNITLQDLVDWQNEKNGNYVI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=135, Percent_Identity=37.037037037037, Blast_Score=94, Evalue=3e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16136; Mature: 16136

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYALRLMMDLAENNTGSPISLKDVAKRQDISDKYLEQIISILNKAGYVRSVRG
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCC
AQGGYMLKMEPQNYTVGMILRQTEGSLAPVACIEDDEIVCDRQQQCVTSIVYKKINDAIS
CCCCEEEEECCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GVVDNITLQDLVDWQNEKNGNYVI
HHHCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKISTKGRYALRLMMDLAENNTGSPISLKDVAKRQDISDKYLEQIISILNKAGYVRSVRG
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCC
AQGGYMLKMEPQNYTVGMILRQTEGSLAPVACIEDDEIVCDRQQQCVTSIVYKKINDAIS
CCCCEEEEECCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GVVDNITLQDLVDWQNEKNGNYVI
HHHCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]