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The map label for this gene is yecS [H]

Identifier: 238922609

GI number: 238922609

Start: 174796

End: 175554

Strand: Direct

Name: yecS [H]

Synonym: EUBREC_0183

Alternate gene names: 238922609

Gene position: 174796-175554 (Clockwise)

Preceding gene: 238922608

Following gene: 238922610

Centisome position: 5.07

GC content: 41.24

Gene sequence:

>759_bases
ATGATGATAAGTAATCCAAGTAATTCGTTAGAATGGATGGTATTTCTGGCGCAGAAATATTCAAGCATGTTTATCAAAGG
AACCTGGCTTACGCTGTACATATCGGTAGTTGGTACATTGCTTGGCTTCGTATTGGGATATATCGTAGGCATAGTAAATG
ATGTAAAGCTTAACGATGGCGACAACATCGTAAAAAAGGTCCTTATCCGTATAGTAAAGGTGATATTTACAGTTTATGTT
GAAGTATTCAGGGACACACCAATGATAGTTCAGGCGATGATTGTGTATTATGGAATACGTCAGATGGGCTATGAAAACCT
GACACCTGTATTTGCAGGTATTCTCGTAACTGTATTAAATACAGGGGCCTACATGGGAGAGACAGTCAGAGCAGGAATCG
GTTCAATAGATATGGGACAGCGCGAGGGCGCATGGGCCATGGGAATGTCACCGTTTAAGACAATGCTCTATGTAGTTTTG
CCGCAGGCATTCAAGAACATCATTCCTGAGATGGCAAATACATTCCTTTTAAATCTGAAGATGACATCAGTGCTCAATGT
TATCGCTGTGCAGGAGCTTTTCATGGCTGCCAAGACAGTCGGTGGAAACTACTACAAGTACTTTGAGTCATATCTGGTCA
TCGCAGTAATTTACTTTGTACTTTGCTTTGTATTTGATAAGCTCTTCAAGCTGATTGAAAAGAAGCTGCAGGGCAAGACA
GACTATGCACTCGCAGTTGAGTACATGGACAATGAATAG

Upstream 100 bases:

>100_bases
AGATGAAAGACTGTGGGATGATGTTATATCGCATCATCCCACAATAGTCTGATAAACCGGCGTAAGCTGGGGATTAGAGA
GATAAAAGTGAGGTAGCAGT

Downstream 100 bases:

>100_bases
GAGGCACAATATGAGTGAGACAGTAATTTCAATTAAGGATTTAAGCAAATCATTTGGTGATCATGAGGTACTTAGAAAGA
TTGATATTGATGTGCATTCC

Product: ABC-type amino acid transport/signal transduction system, periplasmic component/domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MMISNPSNSLEWMVFLAQKYSSMFIKGTWLTLYISVVGTLLGFVLGYIVGIVNDVKLNDGDNIVKKVLIRIVKVIFTVYV
EVFRDTPMIVQAMIVYYGIRQMGYENLTPVFAGILVTVLNTGAYMGETVRAGIGSIDMGQREGAWAMGMSPFKTMLYVVL
PQAFKNIIPEMANTFLLNLKMTSVLNVIAVQELFMAAKTVGGNYYKYFESYLVIAVIYFVLCFVFDKLFKLIEKKLQGKT
DYALAVEYMDNE

Sequences:

>Translated_252_residues
MMISNPSNSLEWMVFLAQKYSSMFIKGTWLTLYISVVGTLLGFVLGYIVGIVNDVKLNDGDNIVKKVLIRIVKVIFTVYV
EVFRDTPMIVQAMIVYYGIRQMGYENLTPVFAGILVTVLNTGAYMGETVRAGIGSIDMGQREGAWAMGMSPFKTMLYVVL
PQAFKNIIPEMANTFLLNLKMTSVLNVIAVQELFMAAKTVGGNYYKYFESYLVIAVIYFVLCFVFDKLFKLIEKKLQGKT
DYALAVEYMDNE
>Mature_252_residues
MMISNPSNSLEWMVFLAQKYSSMFIKGTWLTLYISVVGTLLGFVLGYIVGIVNDVKLNDGDNIVKKVLIRIVKVIFTVYV
EVFRDTPMIVQAMIVYYGIRQMGYENLTPVFAGILVTVLNTGAYMGETVRAGIGSIDMGQREGAWAMGMSPFKTMLYVVL
PQAFKNIIPEMANTFLLNLKMTSVLNVIAVQELFMAAKTVGGNYYKYFESYLVIAVIYFVLCFVFDKLFKLIEKKLQGKT
DYALAVEYMDNE

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=213, Percent_Identity=35.2112676056338, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1787030, Length=218, Percent_Identity=29.8165137614679, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788645, Length=167, Percent_Identity=29.940119760479, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082239, Length=187, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787087, Length=182, Percent_Identity=24.7252747252747, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786874, Length=245, Percent_Identity=25.3061224489796, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786873, Length=165, Percent_Identity=28.4848484848485, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788646, Length=241, Percent_Identity=21.5767634854772, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787086, Length=226, Percent_Identity=26.5486725663717, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28448; Mature: 28448

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEEEEECCCC
>Mature Secondary Structure
MMISNPSNSLEWMVFLAQKYSSMFIKGTWLTLYISVVGTLLGFVLGYIVGIVNDVKLNDG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC
DNIVKKVLIRIVKVIFTVYVEVFRDTPMIVQAMIVYYGIRQMGYENLTPVFAGILVTVLN
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TGAYMGETVRAGIGSIDMGQREGAWAMGMSPFKTMLYVVLPQAFKNIIPEMANTFLLNLK
CCHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSVLNVIAVQELFMAAKTVGGNYYKYFESYLVIAVIYFVLCFVFDKLFKLIEKKLQGKT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DYALAVEYMDNE
CCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]