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The map label for this gene is atpA [H]

Identifier: 238922548

GI number: 238922548

Start: 116375

End: 117880

Strand: Direct

Name: atpA [H]

Synonym: EUBREC_0122

Alternate gene names: 238922548

Gene position: 116375-117880 (Clockwise)

Preceding gene: 238922547

Following gene: 238922549

Centisome position: 3.37

GC content: 48.01

Gene sequence:

>1506_bases
ATGAATCTAAAGCCGGAAGAAATCAGCTCAGTAATAAAGGAGCAGATTAAAAGATACGCTTCCCAGCTCGAAGTCGCTGA
TGTAGGAACAGTCATTCAGGTGGCAGACGGAATCGCACGTATTCATGGTCTTGAGAATGCGATGCAGGGAGAGCTTTTGG
AATTTCCAGGGGAAGTATATGGAATGGTATTAAACCTCGAGGAGGACAATGTCGGTGCTGTTTTACTTGGACAGCAGCGC
AATATCAACGAGGGAGATACAGTTAAGACCACAGGACGAGTGGTAGAGGTGCCGGTAGGCGATGCGATGCTCGGCCGAGT
AGTAAATGCGCTCGGACAGCCAATCGACGGAAAGGGACCTATCCAGTCGGACAAATATCGTCAGATAGAGAGAGTAGCAT
CGGGAGTTATCTCGAGAAAGTCAGTAGATACACCGCTTCAGACCGGTATAAAGGCTATTGACTCAATGGTTCCTATCGGA
CGAGGACAAAGAGAGCTTATTATCGGAGACAGACAGACCGGAAAGACGGCTATCGCGATAGATACCATCATCAACCAGAA
GGGACAGGGTGTGAAATGTATCTATGTAGCTATCGGTCAGAAGGCTTCTACGGTTGCATCCATAGTAAATGAGCTCGAGG
AGTTCGGAGCCATGAGCTACACGACAGTAGTGGCTGCGACAGCATCAGAGCTTGCACCGTTACAGTATATCGCACCATAC
TCAGGCTGCGCTATAGGTGAGGAATGGATGGAAAACGGACAGGATGTGCTCATAGTTTACGATGATCTGAGTAAGCATGC
AGCAGCATACCGTACACTTTCACTCCTCTTAAAGAGAGCGCCCGGACGAGAGGCTTATCCGGGAGATGTTTTCTATCTCC
ATTCAAGGCTTCTGGAGAGAGCAGCGAGACTGTCAGACAAGCTGGGTGGAGGCTCACTCACAGCCCTTCCTATCATTGAG
ACACAGGCGGGTGATGTATCGGCATATATCCCGACCAATGTTATCTCAATCACAGACGGTCAGATATATCTCGAGACAGA
GATGTTCAACGCGGGCTTCAGACCTGCCATAAATGCCGGACTTTCAGTTTCACGAGTTGGAGGCTCGGCACAGATAAAGG
CAATGAAAAAGATTGCAGCACCTATCCGAGTAGAGCTGGCTCAGTACAGAGAGCTTGCAGCGTTCTCACAGTTTGGCTCA
GAGCTTGATGCAAGCACAGCAGAGCAGCTCGCACAGGGAGCACGAATCAAGGAGATTTTAAAGCAGCCGCAGTACAAGCC
GATGCCTGTAGAGAAGCAGGTTATCATAATATACGCTGCGACAAAGAAGTATCTTATCGATATCAAAATCGAGGATATTT
TAAGATTTGAGGCAGAGCTGTTTGATTTCATTGATACCAGATATCCTGAGATTCCTGAAGCAATCAGGGAGAAAAAGGTG
ATGGACGATGATACGGAGCAGGCACTTATAAAGGCAATCGAGGAATGCAAAAAGCAGTTCCGTTAG

Upstream 100 bases:

>100_bases
GAATCGGGGACAGAGTGGTGGATTCATCTGTCAGCAGCAGATTAGAAAGACTCACCCGCGATTTGACAAAAATACAATTG
AAAGTAGGTGAATGCGCTCC

Downstream 100 bases:

>100_bases
ACGGTTGGATATTAGTAGAAGGCAGGTGGTAAAATGGCTTCGATGCGAGACATAAAGCGCAGAAAAAGCAGTATTACAAG
TACTCAGCAGATCACAAAGG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MNLKPEEISSVIKEQIKRYASQLEVADVGTVIQVADGIARIHGLENAMQGELLEFPGEVYGMVLNLEEDNVGAVLLGQQR
NINEGDTVKTTGRVVEVPVGDAMLGRVVNALGQPIDGKGPIQSDKYRQIERVASGVISRKSVDTPLQTGIKAIDSMVPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGQGVKCIYVAIGQKASTVASIVNELEEFGAMSYTTVVAATASELAPLQYIAPY
SGCAIGEEWMENGQDVLIVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLERAARLSDKLGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLETEMFNAGFRPAINAGLSVSRVGGSAQIKAMKKIAAPIRVELAQYRELAAFSQFGS
ELDASTAEQLAQGARIKEILKQPQYKPMPVEKQVIIIYAATKKYLIDIKIEDILRFEAELFDFIDTRYPEIPEAIREKKV
MDDDTEQALIKAIEECKKQFR

Sequences:

>Translated_501_residues
MNLKPEEISSVIKEQIKRYASQLEVADVGTVIQVADGIARIHGLENAMQGELLEFPGEVYGMVLNLEEDNVGAVLLGQQR
NINEGDTVKTTGRVVEVPVGDAMLGRVVNALGQPIDGKGPIQSDKYRQIERVASGVISRKSVDTPLQTGIKAIDSMVPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGQGVKCIYVAIGQKASTVASIVNELEEFGAMSYTTVVAATASELAPLQYIAPY
SGCAIGEEWMENGQDVLIVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLERAARLSDKLGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLETEMFNAGFRPAINAGLSVSRVGGSAQIKAMKKIAAPIRVELAQYRELAAFSQFGS
ELDASTAEQLAQGARIKEILKQPQYKPMPVEKQVIIIYAATKKYLIDIKIEDILRFEAELFDFIDTRYPEIPEAIREKKV
MDDDTEQALIKAIEECKKQFR
>Mature_501_residues
MNLKPEEISSVIKEQIKRYASQLEVADVGTVIQVADGIARIHGLENAMQGELLEFPGEVYGMVLNLEEDNVGAVLLGQQR
NINEGDTVKTTGRVVEVPVGDAMLGRVVNALGQPIDGKGPIQSDKYRQIERVASGVISRKSVDTPLQTGIKAIDSMVPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGQGVKCIYVAIGQKASTVASIVNELEEFGAMSYTTVVAATASELAPLQYIAPY
SGCAIGEEWMENGQDVLIVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLERAARLSDKLGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLETEMFNAGFRPAINAGLSVSRVGGSAQIKAMKKIAAPIRVELAQYRELAAFSQFGS
ELDASTAEQLAQGARIKEILKQPQYKPMPVEKQVIIIYAATKKYLIDIKIEDILRFEAELFDFIDTRYPEIPEAIREKKV
MDDDTEQALIKAIEECKKQFR

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=491, Percent_Identity=58.4521384928717, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI4757810, Length=491, Percent_Identity=58.4521384928717, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI19913426, Length=305, Percent_Identity=28.5245901639344, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913428, Length=306, Percent_Identity=28.4313725490196, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI32189394, Length=310, Percent_Identity=25.1612903225806, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1790172, Length=508, Percent_Identity=57.8740157480315, Blast_Score=603, Evalue=1e-174,
Organism=Escherichia coli, GI1790170, Length=302, Percent_Identity=25.4966887417219, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=27.5735294117647, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=503, Percent_Identity=57.6540755467197, Blast_Score=586, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI71988080, Length=503, Percent_Identity=57.6540755467197, Blast_Score=584, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI71988074, Length=491, Percent_Identity=54.5824847250509, Blast_Score=526, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17570191, Length=330, Percent_Identity=28.1818181818182, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=302, Percent_Identity=28.476821192053, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=310, Percent_Identity=24.8387096774194, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=64.7058823529412, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319370, Length=505, Percent_Identity=56.039603960396, Blast_Score=572, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=28.5245901639344, Blast_Score=119, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=373, Percent_Identity=26.2734584450402, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24658560, Length=471, Percent_Identity=60.0849256900212, Blast_Score=573, Evalue=1e-163,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24638766, Length=310, Percent_Identity=26.1290322580645, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI28574560, Length=329, Percent_Identity=26.4437689969605, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583988, Length=245, Percent_Identity=24.8979591836735, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583986, Length=245, Percent_Identity=24.8979591836735, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583984, Length=245, Percent_Identity=24.8979591836735, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583992, Length=245, Percent_Identity=24.8979591836735, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54736; Mature: 54736

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKPEEISSVIKEQIKRYASQLEVADVGTVIQVADGIARIHGLENAMQGELLEFPGEVY
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCE
GMVLNLEEDNVGAVLLGQQRNINEGDTVKTTGRVVEVPVGDAMLGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEECCCCCCCCCCCEEECCCEEEECCCHHHHHHHHHHHCCCCCCCCC
IQSDKYRQIERVASGVISRKSVDTPLQTGIKAIDSMVPIGRGQRELIIGDRQTGKTAIAI
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
DTIINQKGQGVKCIYVAIGQKASTVASIVNELEEFGAMSYTTVVAATASELAPLQYIAPY
EHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCC
SGCAIGEEWMENGQDVLIVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLER
CCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AARLSDKLGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLETEMFNAGFRPAINAG
HHHHHHCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEEHHCCCCCHHHHCC
LSVSRVGGSAQIKAMKKIAAPIRVELAQYRELAAFSQFGSELDASTAEQLAQGARIKEIL
CEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
KQPQYKPMPVEKQVIIIYAATKKYLIDIKIEDILRFEAELFDFIDTRYPEIPEAIREKKV
HCCCCCCCCCCCEEEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
MDDDTEQALIKAIEECKKQFR
CCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLKPEEISSVIKEQIKRYASQLEVADVGTVIQVADGIARIHGLENAMQGELLEFPGEVY
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCE
GMVLNLEEDNVGAVLLGQQRNINEGDTVKTTGRVVEVPVGDAMLGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEECCCCCCCCCCCEEECCCEEEECCCHHHHHHHHHHHCCCCCCCCC
IQSDKYRQIERVASGVISRKSVDTPLQTGIKAIDSMVPIGRGQRELIIGDRQTGKTAIAI
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
DTIINQKGQGVKCIYVAIGQKASTVASIVNELEEFGAMSYTTVVAATASELAPLQYIAPY
EHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCC
SGCAIGEEWMENGQDVLIVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLER
CCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AARLSDKLGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLETEMFNAGFRPAINAG
HHHHHHCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEEHHCCCCCHHHHCC
LSVSRVGGSAQIKAMKKIAAPIRVELAQYRELAAFSQFGSELDASTAEQLAQGARIKEIL
CEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
KQPQYKPMPVEKQVIIIYAATKKYLIDIKIEDILRFEAELFDFIDTRYPEIPEAIREKKV
HCCCCCCCCCCCEEEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
MDDDTEQALIKAIEECKKQFR
CCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA