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The map label for this gene is yrbG [C]

Identifier: 238922152

GI number: 238922152

Start: 343042

End: 344160

Strand: Reverse

Name: yrbG [C]

Synonym: EUBELI_20387

Alternate gene names: 238922152

Gene position: 344160-343042 (Counterclockwise)

Preceding gene: 238922153

Following gene: 238922151

Centisome position: 54.91

GC content: 36.1

Gene sequence:

>1119_bases
ATGAGACTCATGTATATCAATTATTTTCAGTGTGCAATATCACTGAATCTGGTTGATATACATGAGTTTTTTTATATCCC
TCGGAAAAAGAAAAAGCAGAAAAATAAGGAGATTTATATGGGTGATTTTATTAATAACGCGCCATTTGCGCTTGTAATTG
TGTTCCTGATTATTGGATTTGTGCTGCTTATTAAAGGTGCAGACTTTTTCGTAGAAGGAAGCTCAAGTGTAGCAAAGAGA
CTACATGTTCCGTCTATTATTATTGGACTTACAATTGTTGCAATGGGAACATCGCTTCCAGAAACGGCGGTCAGTGTATC
TGCATCAATTACAGGCAACAATGAACTTGCAGTAAGTAATGTAGTCGGTTCTAATATATTTAACCTGATGGTTGTTATTG
GCGTGTGTGCAATGATTGCAACAGTAAATGTTGCAAAAGAAACAATAAAAAGAGATATCCCATTTTCACTTATCTGTGCA
GGACTTTTATTGATTTTAGGAATCCTTGGGGTTGGTGATAAGTCAGGAATGATGCTTGGACATTTTGATGGTGTAATATT
TATCGGTGCATTTGCAGGATACATTTTTTACATGATTAAGATTGCACTAAAGGCAAGCAAAGAAGGCAAAAAAATCGAGA
TTGAGGGCGGTTCTGATGAAGATATTAAGTTGATTTCAGTTCCGCTTAGTATTCTGTTTATTATTGGCGGTGCGGCTGCG
ATTGCAGTAGGCGGAGATATTACCGTAGACGCTGCCTCAAGGATAGCGAGTGACCTTGGAATGAGCCAGACACTTATCGG
ACTTACAATAGTTTCAATAGGAACATCACTTCCAGAACTTGTAACTTCAATAGTTGCAGCCAGAAAGAATGAAGTCGATA
TGGCACTTGGTAATGCAATTGGTTCAAATGTATTTAACATACTTATGGTACTTGGTATTGCATCAGCAATCAGTCCAATC
AGCATAATTACAGAAAATATTATAGATTTGTGTGTGCTTATTGTATTTACAATATGTGTATGGATATTTGCTGGAACAAA
GAAGAAAATCGGAAGAATCGAAGGTTTTTCAATGGTTGCACTTTATGTGATATATGCAGTTTATATCATAATAAGATAA

Upstream 100 bases:

>100_bases
TCAAGTAACTTAATATTCCATGAGGGAGTAGTTAGCGCGTAAGTGTGATTTGTCAACATTCTGATTATAATAGAGAGTAT
AATCTGGCAAATCTTAAATA

Downstream 100 bases:

>100_bases
ATGAGGTAACATACAAATGCTGTTGTTTTTAAAAGTGTTTTTTACTGAATTCATAGCTGAGATGGGCGATAAAACCCAGC
TCATGCTTATTGCTCTTACT

Product: hypothetical protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRLMYINYFQCAISLNLVDIHEFFYIPRKKKKQKNKEIYMGDFINNAPFALVIVFLIIGFVLLIKGADFFVEGSSSVAKR
LHVPSIIIGLTIVAMGTSLPETAVSVSASITGNNELAVSNVVGSNIFNLMVVIGVCAMIATVNVAKETIKRDIPFSLICA
GLLLILGILGVGDKSGMMLGHFDGVIFIGAFAGYIFYMIKIALKASKEGKKIEIEGGSDEDIKLISVPLSILFIIGGAAA
IAVGGDITVDAASRIASDLGMSQTLIGLTIVSIGTSLPELVTSIVAARKNEVDMALGNAIGSNVFNILMVLGIASAISPI
SIITENIIDLCVLIVFTICVWIFAGTKKKIGRIEGFSMVALYVIYAVYIIIR

Sequences:

>Translated_372_residues
MRLMYINYFQCAISLNLVDIHEFFYIPRKKKKQKNKEIYMGDFINNAPFALVIVFLIIGFVLLIKGADFFVEGSSSVAKR
LHVPSIIIGLTIVAMGTSLPETAVSVSASITGNNELAVSNVVGSNIFNLMVVIGVCAMIATVNVAKETIKRDIPFSLICA
GLLLILGILGVGDKSGMMLGHFDGVIFIGAFAGYIFYMIKIALKASKEGKKIEIEGGSDEDIKLISVPLSILFIIGGAAA
IAVGGDITVDAASRIASDLGMSQTLIGLTIVSIGTSLPELVTSIVAARKNEVDMALGNAIGSNVFNILMVLGIASAISPI
SIITENIIDLCVLIVFTICVWIFAGTKKKIGRIEGFSMVALYVIYAVYIIIR
>Mature_372_residues
MRLMYINYFQCAISLNLVDIHEFFYIPRKKKKQKNKEIYMGDFINNAPFALVIVFLIIGFVLLIKGADFFVEGSSSVAKR
LHVPSIIIGLTIVAMGTSLPETAVSVSASITGNNELAVSNVVGSNIFNLMVVIGVCAMIATVNVAKETIKRDIPFSLICA
GLLLILGILGVGDKSGMMLGHFDGVIFIGAFAGYIFYMIKIALKASKEGKKIEIEGGSDEDIKLISVPLSILFIIGGAAA
IAVGGDITVDAASRIASDLGMSQTLIGLTIVSIGTSLPELVTSIVAARKNEVDMALGNAIGSNVFNILMVLGIASAISPI
SIITENIIDLCVLIVFTICVWIFAGTKKKIGRIEGFSMVALYVIYAVYIIIR

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300796347, Length=148, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI9966787, Length=148, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1789587, Length=283, Percent_Identity=31.8021201413428, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 39727; Mature: 39727

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLMYINYFQCAISLNLVDIHEFFYIPRKKKKQKNKEIYMGDFINNAPFALVIVFLIIGF
CEEEEEEEEEEEEEEEEEEHHHHHCCCCHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHH
VLLIKGADFFVEGSSSVAKRLHVPSIIIGLTIVAMGTSLPETAVSVSASITGNNELAVSN
HHHHCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHEEEEEECCCCCEEEHH
VVGSNIFNLMVVIGVCAMIATVNVAKETIKRDIPFSLICAGLLLILGILGVGDKSGMMLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
HFDGVIFIGAFAGYIFYMIKIALKASKEGKKIEIEGGSDEDIKLISVPLSILFIIGGAAA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHCCHHE
IAVGGDITVDAASRIASDLGMSQTLIGLTIVSIGTSLPELVTSIVAARKNEVDMALGNAI
EEECCCEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHH
GSNVFNILMVLGIASAISPISIITENIIDLCVLIVFTICVWIFAGTKKKIGRIEGFSMVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHH
LYVIYAVYIIIR
HHHHHHHHHHCC
>Mature Secondary Structure
MRLMYINYFQCAISLNLVDIHEFFYIPRKKKKQKNKEIYMGDFINNAPFALVIVFLIIGF
CEEEEEEEEEEEEEEEEEEHHHHHCCCCHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHH
VLLIKGADFFVEGSSSVAKRLHVPSIIIGLTIVAMGTSLPETAVSVSASITGNNELAVSN
HHHHCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHEEEEEECCCCCEEEHH
VVGSNIFNLMVVIGVCAMIATVNVAKETIKRDIPFSLICAGLLLILGILGVGDKSGMMLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
HFDGVIFIGAFAGYIFYMIKIALKASKEGKKIEIEGGSDEDIKLISVPLSILFIIGGAAA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHCCHHE
IAVGGDITVDAASRIASDLGMSQTLIGLTIVSIGTSLPELVTSIVAARKNEVDMALGNAI
EEECCCEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHH
GSNVFNILMVLGIASAISPISIITENIIDLCVLIVFTICVWIFAGTKKKIGRIEGFSMVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHH
LYVIYAVYIIIR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]