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The map label for this gene is yeeO [C]

Identifier: 238922104

GI number: 238922104

Start: 287608

End: 288948

Strand: Reverse

Name: yeeO [C]

Synonym: EUBELI_20339

Alternate gene names: 238922104

Gene position: 288948-287608 (Counterclockwise)

Preceding gene: 238922105

Following gene: 238922103

Centisome position: 46.1

GC content: 38.03

Gene sequence:

>1341_bases
ATGCAAAGTGATTTTTCACAGGGAAAAGTCTGGAAAAATGTTATTAATCAGGCAATTCCGCTTATGGTCGCACAGCTTAT
ACAGATTCTGTACAATGTTGTTGACCGGATATACATTGGGCATCTTCCTGTTATTGGAAGCAATGCTTTAACAGGAATAG
GACTGGTTTTTCCTATTACAACACTTGTTGCGGCATTTACTAATCTGTTTTCAACAGGTGGTGTGCCGCTCTTTTCTATG
GCAAGAGGAGCAAAAGAAGAAAAGAAAGCGGAACTTATACTAGGACAGGTTGTATCACTGCTTTTTATTACATCGCTGGC
ACTTATGGCGTTATGCTATATATTTAAAAGACCAGTACTGTTCCTTTTCGGAGCAAGTGAAGAAACTTATGTATATGCTG
ACCAGTATCTTAAAATATATCTTCTGGGAACGATATTTTCAGTGCTTTCAACCGGACTTAATGGATTTATTAATGCGCAG
GGATATCCTAAAAAGGGCATGATGACAGTTATGCTTGGTGCAATTATTAATCTCATTCTTGATCCAGTGTTCATATATGG
GCTTCATATGGGCGTTTATGGTGCAGCAATAGCAACAGTAATAAGCCAGGGGGTGTCTTTTGCGTGGGTTTTAAGCTTTT
TTATGGGGGAGAAAACATTTTACCATATAAAAAAAGAAAATCTGATTCTGAAAGCACGAATGTTTGGAAAGATTACATCT
CTTGGAATATCAGGATTTGTTATGCAGGGAACTAACTGCCTTGTGCAGATTGTATGTAATAAAATGCTGTTTATGTATGG
CGGGGATATGTATGTAGGAATTATGACTGTAATTAATTCAGTCAGGGAGATTCTTTCTGTTCCTGGTAGTACACTTGGTA
GTGGAGCACAACCTGTTCTTGGCTACAATTATGGTGCAAAGCAATACGAAAGAGTCAGAAAAGCAATAAGATTTACGGCT
GCGATTGGATTTTTATATATGCTTATTGCGTGGCTTGCTGTAATTATATTTCCGAAAGAGATTCTGTCGGTATTTACAAC
GGATAAGGCAATGATTAATTTAGGAGAACATGCATTGAAGCTGTATTTCTTTGGGTTTTTCTTTATGTCGTTCCAGTTCG
TGGGACAGTCGACATTTACAGCTCTTGGATGTGCGAAGAGAGCTGTGTTCTTTTCAATATTCAGGAAGGTTATAATTGTT
GTTCCGCTTACAATTATTCTTCCTATGCTTGGACTTGGAGTTGAAGGAGTGTTTATTGCTGAGCCGGTATCTAATGCAAT
AGGTGGTCTGGCAAGCTTTACTACAATGTATTTTACACTTTACAAAAAACTGCCGGAATAG

Upstream 100 bases:

>100_bases
CTTCTAAGACAGCTGGTACTGCTGCAACAGGCAACAAAGCACCAGATATCATTGTAGATGCCAAAGATATTAAAGAACAT
GTAAGTGATGAGGAATAGTA

Downstream 100 bases:

>100_bases
TATTCTAAAGACAATGATAGCAAAGGTGCCATCGCTTCTGTATAGGGAGCGGTGGCTTTTTTAAAATCTTGGAAAGAGGG
ATAATTTATGGATATATTTG

Product: multidrug resistance protein, MATE family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MQSDFSQGKVWKNVINQAIPLMVAQLIQILYNVVDRIYIGHLPVIGSNALTGIGLVFPITTLVAAFTNLFSTGGVPLFSM
ARGAKEEKKAELILGQVVSLLFITSLALMALCYIFKRPVLFLFGASEETYVYADQYLKIYLLGTIFSVLSTGLNGFINAQ
GYPKKGMMTVMLGAIINLILDPVFIYGLHMGVYGAAIATVISQGVSFAWVLSFFMGEKTFYHIKKENLILKARMFGKITS
LGISGFVMQGTNCLVQIVCNKMLFMYGGDMYVGIMTVINSVREILSVPGSTLGSGAQPVLGYNYGAKQYERVRKAIRFTA
AIGFLYMLIAWLAVIIFPKEILSVFTTDKAMINLGEHALKLYFFGFFFMSFQFVGQSTFTALGCAKRAVFFSIFRKVIIV
VPLTIILPMLGLGVEGVFIAEPVSNAIGGLASFTTMYFTLYKKLPE

Sequences:

>Translated_446_residues
MQSDFSQGKVWKNVINQAIPLMVAQLIQILYNVVDRIYIGHLPVIGSNALTGIGLVFPITTLVAAFTNLFSTGGVPLFSM
ARGAKEEKKAELILGQVVSLLFITSLALMALCYIFKRPVLFLFGASEETYVYADQYLKIYLLGTIFSVLSTGLNGFINAQ
GYPKKGMMTVMLGAIINLILDPVFIYGLHMGVYGAAIATVISQGVSFAWVLSFFMGEKTFYHIKKENLILKARMFGKITS
LGISGFVMQGTNCLVQIVCNKMLFMYGGDMYVGIMTVINSVREILSVPGSTLGSGAQPVLGYNYGAKQYERVRKAIRFTA
AIGFLYMLIAWLAVIIFPKEILSVFTTDKAMINLGEHALKLYFFGFFFMSFQFVGQSTFTALGCAKRAVFFSIFRKVIIV
VPLTIILPMLGLGVEGVFIAEPVSNAIGGLASFTTMYFTLYKKLPE
>Mature_446_residues
MQSDFSQGKVWKNVINQAIPLMVAQLIQILYNVVDRIYIGHLPVIGSNALTGIGLVFPITTLVAAFTNLFSTGGVPLFSM
ARGAKEEKKAELILGQVVSLLFITSLALMALCYIFKRPVLFLFGASEETYVYADQYLKIYLLGTIFSVLSTGLNGFINAQ
GYPKKGMMTVMLGAIINLILDPVFIYGLHMGVYGAAIATVISQGVSFAWVLSFFMGEKTFYHIKKENLILKARMFGKITS
LGISGFVMQGTNCLVQIVCNKMLFMYGGDMYVGIMTVINSVREILSVPGSTLGSGAQPVLGYNYGAKQYERVRKAIRFTA
AIGFLYMLIAWLAVIIFPKEILSVFTTDKAMINLGEHALKLYFFGFFFMSFQFVGQSTFTALGCAKRAVFFSIFRKVIIV
VPLTIILPMLGLGVEGVFIAEPVSNAIGGLASFTTMYFTLYKKLPE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49078; Mature: 49078

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSDFSQGKVWKNVINQAIPLMVAQLIQILYNVVDRIYIGHLPVIGSNALTGIGLVFPIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
TLVAAFTNLFSTGGVPLFSMARGAKEEKKAELILGQVVSLLFITSLALMALCYIFKRPVL
HHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FLFGASEETYVYADQYLKIYLLGTIFSVLSTGLNGFINAQGYPKKGMMTVMLGAIINLIL
EEECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHH
DPVFIYGLHMGVYGAAIATVISQGVSFAWVLSFFMGEKTFYHIKKENLILKARMFGKITS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEEECCCEEEHHHHHHHHHH
LGISGFVMQGTNCLVQIVCNKMLFMYGGDMYVGIMTVINSVREILSVPGSTLGSGAQPVL
HCCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GYNYGAKQYERVRKAIRFTAAIGFLYMLIAWLAVIIFPKEILSVFTTDKAMINLGEHALK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LYFFGFFFMSFQFVGQSTFTALGCAKRAVFFSIFRKVIIVVPLTIILPMLGLGVEGVFIA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EPVSNAIGGLASFTTMYFTLYKKLPE
CHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSDFSQGKVWKNVINQAIPLMVAQLIQILYNVVDRIYIGHLPVIGSNALTGIGLVFPIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
TLVAAFTNLFSTGGVPLFSMARGAKEEKKAELILGQVVSLLFITSLALMALCYIFKRPVL
HHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FLFGASEETYVYADQYLKIYLLGTIFSVLSTGLNGFINAQGYPKKGMMTVMLGAIINLIL
EEECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHH
DPVFIYGLHMGVYGAAIATVISQGVSFAWVLSFFMGEKTFYHIKKENLILKARMFGKITS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEEECCCEEEHHHHHHHHHH
LGISGFVMQGTNCLVQIVCNKMLFMYGGDMYVGIMTVINSVREILSVPGSTLGSGAQPVL
HCCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GYNYGAKQYERVRKAIRFTAAIGFLYMLIAWLAVIIFPKEILSVFTTDKAMINLGEHALK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LYFFGFFFMSFQFVGQSTFTALGCAKRAVFFSIFRKVIIVVPLTIILPMLGLGVEGVFIA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EPVSNAIGGLASFTTMYFTLYKKLPE
CHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]