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The map label for this gene is tlpC [H]

Identifier: 238922099

GI number: 238922099

Start: 281746

End: 283599

Strand: Reverse

Name: tlpC [H]

Synonym: EUBELI_20334

Alternate gene names: 238922099

Gene position: 283599-281746 (Counterclockwise)

Preceding gene: 238922100

Following gene: 238922096

Centisome position: 45.25

GC content: 38.62

Gene sequence:

>1854_bases
ATGGGGAAAATGCATACTAAGGCCGAAAGAACTGAAAAAGTTGAAGAGATTAAGGCTGAGAATAGGAAGAAGGTAAAAGA
GATCAGGGCAAAGAAGAAAGAGCTTGATGCTGAGGTTAAGAAGAAAGCCAGACAGGTTGCCGCTGATAGAAAGAAGAGAA
GAGCGGGTATTACATTCAGACTGTTTATGCTTGCTATTGTACCGGTAATTGTTATGGTACTGGGGCTTATTACAACTACA
GTATTCAGTCTTAAGTCAGGACTGGAAGAAGAGGCCATGGATGGACTAGAACTGTTAAGTGGGGCAGTACAGAGTTCTTA
TGAGGATATTAAAGGCAACTATGAATATAAGAACGGTAGATTATTCAAGGGTGGCGAAGAATTGACTATTAAACCGGCTG
CACTTGATATATATGTCAAGAACTCCAAGAATGATGTCCAGGTTACACTTACATATGGAACCAAGAGAGTTCTTACAACG
CTTACTGATAAAAAGGGAGCAAGATTAACGGGAACAGATATATCAAGTGAAGTGTGGGATGTAGTTAAGACGGGAAAGAC
ATATAGAGATACTAATTATAAGGTAGATGGAAAGAGATACTGTGCAGTATATGTGCCACTAAAGGATAATAACCAGGTTG
TAGGATGTGTATTTGCAGGACAGCCTACATCAGATATTACAAACTATATAATGCAGAAGGTTGGAACAATGCTTATAGTT
TCTGCAGTAGTACTTATATTAGTAGGAATTGTGGCAACATTTATAGCACAGAGTATTTCAAAGTCGATTAAGAGAGCAAG
TGTATCTGTAACGAAAGTTGCCGGAGGAGATCTTACAGTAGAGGTCGATAAGACTGTACTTAAGAGAAAGGATGAAATCG
GAGACATGGGCAGAGCCCTTGAAACTCTTATAATTAAGTTAAGAGAAATTGTTGGAAGTCTTGCAAAGTCTGCAACAGAT
CTTGGTGAGTCAGGTAATTCAATTGACTCTATGGCTTCACAGTCAAGTGTTGCTGCAGGAGAAATCAGTACAGCAGTAGA
GGAGATATCTAAGGGTGCAGTATCACAGGCAGAAGATATTGAGACAGCAACTAATGAAATTATGACAATGGGTGAACAGA
TTACTCAGATAGTTAATAATATTGCTGACCTTACAAAGACATCTAAGAACATGGAAGAAGCCGAAAATGCTTCACAGGAT
ACAATGATTGAATTAAGTGATGCAGTACAGAGAACTACTGATGCAGTTGCAAGAATTGCAAAACAGATAGAGACAACTAA
TGAATCGGTAGATAAGATTGGCAATGCTGCTTCACTTATTGCAGATATTGCAAGCCAGACAAGCCTGTTATCACTGAATG
CTTCTATTGAATCAGCAAGAGCAGGAGAAGCAGGAAAAGGATTTGCAGTTGTTGCATCAGAGATTCAGAAGCTTTCATCA
CAATCTGACAGCACAGCAAGTAAGATTCAGGAGATTATTACAGATCTCCAGAATGATTCGAAAGAAACACTTGAGGTTAT
GAGAAGTACAGAAGTTCTTGTAAGAGAGCAGTATGAAAAGCTTGCAGCAACTAAGGAAAGATTTAAGGAAGTTGGTAATG
GCATTAATGTTTCAAAGCGTGGAACAGATGTTATTAAAGGCAATGCCGAAGTATGCGACAGCTCAAGAGTTACCGTTGTT
GATGTAATATCTAATCTATCTGCTATATCAGAAGAGAATGCTGCTTCAACACAGCAGACAACATCTTCTATGCAGGAGCT
TAATGCAACTATTAATATTCTTGCAGAAACAGCGGCTAAGGTTAAGGAAGTATCAGACCAGCTTAATGAAGATATGAAGT
ATTTTAAGATGTAA

Upstream 100 bases:

>100_bases
AGGTTTTTAAAATTGGCGTAATGGTGTATAATTTAAAGAACAATATGAACAAAAGAATGTTCTGGTGAATAATTAAATAA
GAGGAAAGGGAGGTCTTATA

Downstream 100 bases:

>100_bases
TCAGAATAAAGATACCGGTTAAGTTTGTATATATTAAGAACTTAACCGGTAATTTTTTATGCTTTTTCTAGTACATTTAT
TAATTCCTTTAGCTGTGCCC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MGKMHTKAERTEKVEEIKAENRKKVKEIRAKKKELDAEVKKKARQVAADRKKRRAGITFRLFMLAIVPVIVMVLGLITTT
VFSLKSGLEEEAMDGLELLSGAVQSSYEDIKGNYEYKNGRLFKGGEELTIKPAALDIYVKNSKNDVQVTLTYGTKRVLTT
LTDKKGARLTGTDISSEVWDVVKTGKTYRDTNYKVDGKRYCAVYVPLKDNNQVVGCVFAGQPTSDITNYIMQKVGTMLIV
SAVVLILVGIVATFIAQSISKSIKRASVSVTKVAGGDLTVEVDKTVLKRKDEIGDMGRALETLIIKLREIVGSLAKSATD
LGESGNSIDSMASQSSVAAGEISTAVEEISKGAVSQAEDIETATNEIMTMGEQITQIVNNIADLTKTSKNMEEAENASQD
TMIELSDAVQRTTDAVARIAKQIETTNESVDKIGNAASLIADIASQTSLLSLNASIESARAGEAGKGFAVVASEIQKLSS
QSDSTASKIQEIITDLQNDSKETLEVMRSTEVLVREQYEKLAATKERFKEVGNGINVSKRGTDVIKGNAEVCDSSRVTVV
DVISNLSAISEENAASTQQTTSSMQELNATINILAETAAKVKEVSDQLNEDMKYFKM

Sequences:

>Translated_617_residues
MGKMHTKAERTEKVEEIKAENRKKVKEIRAKKKELDAEVKKKARQVAADRKKRRAGITFRLFMLAIVPVIVMVLGLITTT
VFSLKSGLEEEAMDGLELLSGAVQSSYEDIKGNYEYKNGRLFKGGEELTIKPAALDIYVKNSKNDVQVTLTYGTKRVLTT
LTDKKGARLTGTDISSEVWDVVKTGKTYRDTNYKVDGKRYCAVYVPLKDNNQVVGCVFAGQPTSDITNYIMQKVGTMLIV
SAVVLILVGIVATFIAQSISKSIKRASVSVTKVAGGDLTVEVDKTVLKRKDEIGDMGRALETLIIKLREIVGSLAKSATD
LGESGNSIDSMASQSSVAAGEISTAVEEISKGAVSQAEDIETATNEIMTMGEQITQIVNNIADLTKTSKNMEEAENASQD
TMIELSDAVQRTTDAVARIAKQIETTNESVDKIGNAASLIADIASQTSLLSLNASIESARAGEAGKGFAVVASEIQKLSS
QSDSTASKIQEIITDLQNDSKETLEVMRSTEVLVREQYEKLAATKERFKEVGNGINVSKRGTDVIKGNAEVCDSSRVTVV
DVISNLSAISEENAASTQQTTSSMQELNATINILAETAAKVKEVSDQLNEDMKYFKM
>Mature_616_residues
GKMHTKAERTEKVEEIKAENRKKVKEIRAKKKELDAEVKKKARQVAADRKKRRAGITFRLFMLAIVPVIVMVLGLITTTV
FSLKSGLEEEAMDGLELLSGAVQSSYEDIKGNYEYKNGRLFKGGEELTIKPAALDIYVKNSKNDVQVTLTYGTKRVLTTL
TDKKGARLTGTDISSEVWDVVKTGKTYRDTNYKVDGKRYCAVYVPLKDNNQVVGCVFAGQPTSDITNYIMQKVGTMLIVS
AVVLILVGIVATFIAQSISKSIKRASVSVTKVAGGDLTVEVDKTVLKRKDEIGDMGRALETLIIKLREIVGSLAKSATDL
GESGNSIDSMASQSSVAAGEISTAVEEISKGAVSQAEDIETATNEIMTMGEQITQIVNNIADLTKTSKNMEEAENASQDT
MIELSDAVQRTTDAVARIAKQIETTNESVDKIGNAASLIADIASQTSLLSLNASIESARAGEAGKGFAVVASEIQKLSSQ
SDSTASKIQEIITDLQNDSKETLEVMRSTEVLVREQYEKLAATKERFKEVGNGINVSKRGTDVIKGNAEVCDSSRVTVVD
VISNLSAISEENAASTQQTTSSMQELNATINILAETAAKVKEVSDQLNEDMKYFKM

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=267, Percent_Identity=32.9588014981273, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787690, Length=265, Percent_Identity=30.9433962264151, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=273, Percent_Identity=28.9377289377289, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788195, Length=208, Percent_Identity=32.6923076923077, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788194, Length=124, Percent_Identity=38.7096774193548, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66874; Mature: 66743

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKMHTKAERTEKVEEIKAENRKKVKEIRAKKKELDAEVKKKARQVAADRKKRRAGITFR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LFMLAIVPVIVMVLGLITTTVFSLKSGLEEEAMDGLELLSGAVQSSYEDIKGNYEYKNGR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCE
LFKGGEELTIKPAALDIYVKNSKNDVQVTLTYGTKRVLTTLTDKKGARLTGTDISSEVWD
EEECCCCEEEEEEEEEEEEECCCCCEEEEEEECCHHHHHHHHCCCCCEEECCCCHHHHHH
VVKTGKTYRDTNYKVDGKRYCAVYVPLKDNNQVVGCVFAGQPTSDITNYIMQKVGTMLIV
HHHCCCCCCCCCEEECCCEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
SAVVLILVGIVATFIAQSISKSIKRASVSVTKVAGGDLTVEVDKTVLKRKDEIGDMGRAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHH
ETLIIKLREIVGSLAKSATDLGESGNSIDSMASQSSVAAGEISTAVEEISKGAVSQAEDI
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ETATNEIMTMGEQITQIVNNIADLTKTSKNMEEAENASQDTMIELSDAVQRTTDAVARIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KQIETTNESVDKIGNAASLIADIASQTSLLSLNASIESARAGEAGKGFAVVASEIQKLSS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHC
QSDSTASKIQEIITDLQNDSKETLEVMRSTEVLVREQYEKLAATKERFKEVGNGINVSKR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GTDVIKGNAEVCDSSRVTVVDVISNLSAISEENAASTQQTTSSMQELNATINILAETAAK
CCHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VKEVSDQLNEDMKYFKM
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKMHTKAERTEKVEEIKAENRKKVKEIRAKKKELDAEVKKKARQVAADRKKRRAGITFR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LFMLAIVPVIVMVLGLITTTVFSLKSGLEEEAMDGLELLSGAVQSSYEDIKGNYEYKNGR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCE
LFKGGEELTIKPAALDIYVKNSKNDVQVTLTYGTKRVLTTLTDKKGARLTGTDISSEVWD
EEECCCCEEEEEEEEEEEEECCCCCEEEEEEECCHHHHHHHHCCCCCEEECCCCHHHHHH
VVKTGKTYRDTNYKVDGKRYCAVYVPLKDNNQVVGCVFAGQPTSDITNYIMQKVGTMLIV
HHHCCCCCCCCCEEECCCEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
SAVVLILVGIVATFIAQSISKSIKRASVSVTKVAGGDLTVEVDKTVLKRKDEIGDMGRAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHH
ETLIIKLREIVGSLAKSATDLGESGNSIDSMASQSSVAAGEISTAVEEISKGAVSQAEDI
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ETATNEIMTMGEQITQIVNNIADLTKTSKNMEEAENASQDTMIELSDAVQRTTDAVARIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KQIETTNESVDKIGNAASLIADIASQTSLLSLNASIESARAGEAGKGFAVVASEIQKLSS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHC
QSDSTASKIQEIITDLQNDSKETLEVMRSTEVLVREQYEKLAATKERFKEVGNGINVSKR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GTDVIKGNAEVCDSSRVTVVDVISNLSAISEENAASTQQTTSSMQELNATINILAETAAK
CCHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VKEVSDQLNEDMKYFKM
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]