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The map label for this gene is mnaA [H]

Identifier: 238922074

GI number: 238922074

Start: 257713

End: 258192

Strand: Reverse

Name: mnaA [H]

Synonym: EUBELI_20309

Alternate gene names: 238922074

Gene position: 258192-257713 (Counterclockwise)

Preceding gene: 238922075

Following gene: 238922073

Centisome position: 41.2

GC content: 44.38

Gene sequence:

>480_bases
ATGCATCATATGTTCAGGGCTATTCGGAGAGTGCTTGATGAACATCCAGAATGTAAGGCGGTATATCCTATTCATATGAA
TCCAGTAGTTCAAAAAGCAGCAGATGAAGAACTGGGGGATTGCAGCCAGATACATATTATTGATCCTATAGAAGTATTTG
ATTGTCATAATTTCGAAGCAAGGTGCCATCTTTGTCTTACAGATTCAGGCGGAATACAGGAAGAATGCCCATCATATGGC
AAGCCTGTACTGGTTATGCGTGATACAACAGAACGCCCGGAAGGTGTTGCAGCCGGTACATTAAGACTGGTTGGAACAGA
CGAGGAGACAATATATCGTAATTTTAAGAAACTTCTGGAGAATCATGAAGCTTATGACGCTATGTCTCATGCGTGCAATC
CATATGGTGACGGCAACGCCTGCAAGAGGATAGCAGATGTGCTTGAGTATGGGGAGTGTGAAGCCTGGGTGGCGGAGTGA

Upstream 100 bases:

>100_bases
TACAGTCAGTGAAGAATATACTCATCCAGAATTAGACTGGGTTGGAGATGGAAAGCTTATATTTATTACTGCTCACAGAA
GGGAAAATTTAGGAGAGCCT

Downstream 100 bases:

>100_bases
GCTGTAAATGGATTATGTTGAGAATGTGGCGGTATTTGATTACAGCAATGCATTTGCAGAAGAAGCAAACAGTTATTTTT
GAGATTACTATAGTTCTCCA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MHHMFRAIRRVLDEHPECKAVYPIHMNPVVQKAADEELGDCSQIHIIDPIEVFDCHNFEARCHLCLTDSGGIQEECPSYG
KPVLVMRDTTERPEGVAAGTLRLVGTDEETIYRNFKKLLENHEAYDAMSHACNPYGDGNACKRIADVLEYGECEAWVAE

Sequences:

>Translated_159_residues
MHHMFRAIRRVLDEHPECKAVYPIHMNPVVQKAADEELGDCSQIHIIDPIEVFDCHNFEARCHLCLTDSGGIQEECPSYG
KPVLVMRDTTERPEGVAAGTLRLVGTDEETIYRNFKKLLENHEAYDAMSHACNPYGDGNACKRIADVLEYGECEAWVAE
>Mature_159_residues
MHHMFRAIRRVLDEHPECKAVYPIHMNPVVQKAADEELGDCSQIHIIDPIEVFDCHNFEARCHLCLTDSGGIQEECPSYG
KPVLVMRDTTERPEGVAAGTLRLVGTDEETIYRNFKKLLENHEAYDAMSHACNPYGDGNACKRIADVLEYGECEAWVAE

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=143, Percent_Identity=50.3496503496504, Blast_Score=147, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 17962; Mature: 17962

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHMFRAIRRVLDEHPECKAVYPIHMNPVVQKAADEELGDCSQIHIIDPIEVFDCHNFEA
CHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEECCHHEECCCCCCC
RCHLCLTDSGGIQEECPSYGKPVLVMRDTTERPEGVAAGTLRLVGTDEETIYRNFKKLLE
EEEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCCEECEEEEEECCHHHHHHHHHHHHH
NHEAYDAMSHACNPYGDGNACKRIADVLEYGECEAWVAE
CCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MHHMFRAIRRVLDEHPECKAVYPIHMNPVVQKAADEELGDCSQIHIIDPIEVFDCHNFEA
CHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEECCHHEECCCCCCC
RCHLCLTDSGGIQEECPSYGKPVLVMRDTTERPEGVAAGTLRLVGTDEETIYRNFKKLLE
EEEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCCEECEEEEEECCHHHHHHHHHHHHH
NHEAYDAMSHACNPYGDGNACKRIADVLEYGECEAWVAE
CCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]