Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 238922043

GI number: 238922043

Start: 225832

End: 226782

Strand: Reverse

Name: fabD [H]

Synonym: EUBELI_20278

Alternate gene names: 238922043

Gene position: 226782-225832 (Counterclockwise)

Preceding gene: 238922044

Following gene: 238922042

Centisome position: 36.18

GC content: 43.01

Gene sequence:

>951_bases
ATGGAACGGAGGAATAAAGTAATGGGAAAAATAGCAGTATTATTTTCAGGTCAGGGTGCACAGTATGTAGGAATGGGCAA
AGACCTATACGATTCAGATTCTGATGCAAAGAAATTATATGATTTGGGGGAGTCGCTCCGCCCGGGAACAGTTAAGGTGT
GCTTTGAAGGAGAAGGCGAGGAGCTTACCAAGACAGAGAATACACAGCCGGCACTTTTCCTTACAGACCTTGCATTTGCC
AATGCGCTTAAGGATGCCGGAATTAAGGCTGACGCTGTAGCAGGATTTTCACTTGGAGAGATTCCGGCGCTTGCTTATGC
AGGAGTTTTATCAATAGAGGACGCATTTAAACTGGTAGTTATCAGAGGAACCAAGATGGGTGAGCTTTCTACAAAGTATG
CAGGCGGAATGGCAGCAGCACTTAAGCTTGCTCCAGAAGTTGTTGAAGAGACATGTAAGGAATTCAAGGAAATCTGGCCG
GTTAATTATAATTGTCCTGGACAGATTTCATGTGCAGGAAGTGCTGAAGAGATAGACGCATTCTGTGAAGCAATCAAGGA
AAAAGGCGGCAGGGCAGTTAAGCTTGCAGTAAGCGGTGCATTCCATACTCCTTATATGAAGGATGCAAGTGAAGAACTTG
AGAAGGCACTTAAGGTAATGACAATTAATGCTCCACAGACAGAGATATATGCCAACAGAACAGGAAAGCCTTATCCACAG
GATACAGCACAGATTATAGAAACAATAGCACTTCAGGCTTCTTCAAGTGTAAGGTTTGAGGATACATTAAAGAATATGTG
GGCTGACGGAATAGACACATTTATCGAGGTAGGAGCAGGAAAGACACTTACAGGATTTGTTAAGAAGACACTTCCAGAAG
CAAAGATGTACACAGTTACAACAGTTGATGCGTTGAATGAAACAATTGAGAACATCAAGGCAGGAGAATAA

Upstream 100 bases:

>100_bases
AACAAGGTTCTCGCATCATTTGACGCAGTAGTTAAGGTAGATGGCAATGTGTACGCAAAGGGAAGCATGACATTTACAAC
AGTAGACCGTAAGGATATAT

Downstream 100 bases:

>100_bases
TAATGACAGTCAAATGTAACAAATGTAAAGAAGAAATCAATAAAGAGGATTTGGAGAAGAATTACTACATATGCCCGTTA
TGCGGGAAGCTAAATCGTAT

Product: [acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MERRNKVMGKIAVLFSGQGAQYVGMGKDLYDSDSDAKKLYDLGESLRPGTVKVCFEGEGEELTKTENTQPALFLTDLAFA
NALKDAGIKADAVAGFSLGEIPALAYAGVLSIEDAFKLVVIRGTKMGELSTKYAGGMAAALKLAPEVVEETCKEFKEIWP
VNYNCPGQISCAGSAEEIDAFCEAIKEKGGRAVKLAVSGAFHTPYMKDASEELEKALKVMTINAPQTEIYANRTGKPYPQ
DTAQIIETIALQASSSVRFEDTLKNMWADGIDTFIEVGAGKTLTGFVKKTLPEAKMYTVTTVDALNETIENIKAGE

Sequences:

>Translated_316_residues
MERRNKVMGKIAVLFSGQGAQYVGMGKDLYDSDSDAKKLYDLGESLRPGTVKVCFEGEGEELTKTENTQPALFLTDLAFA
NALKDAGIKADAVAGFSLGEIPALAYAGVLSIEDAFKLVVIRGTKMGELSTKYAGGMAAALKLAPEVVEETCKEFKEIWP
VNYNCPGQISCAGSAEEIDAFCEAIKEKGGRAVKLAVSGAFHTPYMKDASEELEKALKVMTINAPQTEIYANRTGKPYPQ
DTAQIIETIALQASSSVRFEDTLKNMWADGIDTFIEVGAGKTLTGFVKKTLPEAKMYTVTTVDALNETIENIKAGE
>Mature_316_residues
MERRNKVMGKIAVLFSGQGAQYVGMGKDLYDSDSDAKKLYDLGESLRPGTVKVCFEGEGEELTKTENTQPALFLTDLAFA
NALKDAGIKADAVAGFSLGEIPALAYAGVLSIEDAFKLVVIRGTKMGELSTKYAGGMAAALKLAPEVVEETCKEFKEIWP
VNYNCPGQISCAGSAEEIDAFCEAIKEKGGRAVKLAVSGAFHTPYMKDASEELEKALKVMTINAPQTEIYANRTGKPYPQ
DTAQIIETIALQASSSVRFEDTLKNMWADGIDTFIEVGAGKTLTGFVKKTLPEAKMYTVTTVDALNETIENIKAGE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=337, Percent_Identity=31.4540059347181, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1787334, Length=314, Percent_Identity=34.3949044585987, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71984332, Length=297, Percent_Identity=32.996632996633, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=304, Percent_Identity=26.9736842105263, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=36.5448504983389, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI221330659, Length=304, Percent_Identity=25.6578947368421, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920632, Length=303, Percent_Identity=25.4125412541254, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34016; Mature: 34016

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRNKVMGKIAVLFSGQGAQYVGMGKDLYDSDSDAKKLYDLGESLRPGTVKVCFEGEGE
CCHHHHHHEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCC
ELTKTENTQPALFLTDLAFANALKDAGIKADAVAGFSLGEIPALAYAGVLSIEDAFKLVV
HHCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCEEEEE
IRGTKMGELSTKYAGGMAAALKLAPEVVEETCKEFKEIWPVNYNCPGQISCAGSAEEIDA
EECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHH
FCEAIKEKGGRAVKLAVSGAFHTPYMKDASEELEKALKVMTINAPQTEIYANRTGKPYPQ
HHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEEECCCCCCEEEECCCCCCCCC
DTAQIIETIALQASSSVRFEDTLKNMWADGIDTFIEVGAGKTLTGFVKKTLPEAKMYTVT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEE
TVDALNETIENIKAGE
EHHHHHHHHHHHCCCC
>Mature Secondary Structure
MERRNKVMGKIAVLFSGQGAQYVGMGKDLYDSDSDAKKLYDLGESLRPGTVKVCFEGEGE
CCHHHHHHEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCC
ELTKTENTQPALFLTDLAFANALKDAGIKADAVAGFSLGEIPALAYAGVLSIEDAFKLVV
HHCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCEEEEE
IRGTKMGELSTKYAGGMAAALKLAPEVVEETCKEFKEIWPVNYNCPGQISCAGSAEEIDA
EECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHH
FCEAIKEKGGRAVKLAVSGAFHTPYMKDASEELEKALKVMTINAPQTEIYANRTGKPYPQ
HHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEEECCCCCCEEEECCCCCCCCC
DTAQIIETIALQASSSVRFEDTLKNMWADGIDTFIEVGAGKTLTGFVKKTLPEAKMYTVT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEE
TVDALNETIENIKAGE
EHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]