Click here to switch to the map view.

The map label for this gene is accD2

Identifier: 238922042

GI number: 238922042

Start: 225059

End: 225829

Strand: Reverse

Name: accD2

Synonym: EUBELI_20277

Alternate gene names: 238922042

Gene position: 225829-225059 (Counterclockwise)

Preceding gene: 238922043

Following gene: 238922041

Centisome position: 36.03

GC content: 41.76

Gene sequence:

>771_bases
ATGACAGTCAAATGTAACAAATGTAAAGAAGAAATCAATAAAGAGGATTTGGAGAAGAATTACTACATATGCCCGTTATG
CGGGAAGCTAAATCGTATGCCGGCAAAGAACAGACTTCAGATGCTTACAGAAAAGTTTGATGTAATGTTTAATGATCAGG
AATTTACAGATCCTATTGATTTTCCATCATACAAGGAAAAGTATGAGTCTGCCAGAGAAAAGAGCGGTGAGACAGAGGGC
GTTGTATGCGGCAGAGGAACTATCGGTGGGAATGATACATGTATATTCATTATGGAGCCTAACTTCATGATGGGTTCTAT
GGGAACAGTTGTTGGGGACAGAATTACAGCACTTTTTGAATATGCTACAAAGAACAGACTTCCGGTTATCGGATATACAG
TTTCAGGTGGTGCAAGAATGCAGGAGGGTGCACTGTCACTTATGCAGATGGCAAAGGTTTCAGCAGCAGCCAAGAGACAT
AGTGACGCAGGACTCTTATATGTTGTATGTACAACAGACCCTACAATGGGCGGTGCTACAGCAAGCTTTGCAATGCTTGG
AGATATAATCATATCTGAACCGGGTGCAATGATTGGATTTGCAGGAAAGCGAGTAGTAGAGCAGGTTACAGGTGAAGTGC
TTCCGGATAATTTCCAGAGCGCAGAGTTCCAGTTAAAGAACGGATTTATAGATGATATCGTGCCAAGACAGGAACAGAGG
GCATATCTTGCTAACATTCTTGCAATACATGCAGAAACAGTAAGTGCATAA

Upstream 100 bases:

>100_bases
GATTTGTTAAGAAGACACTTCCAGAAGCAAAGATGTACACAGTTACAACAGTTGATGCGTTGAATGAAACAATTGAGAAC
ATCAAGGCAGGAGAATAATA

Downstream 100 bases:

>100_bases
CAGTATTGCATTGCAATATAAGGAGAAAGATTAATCATGACAAACGAGAATTTAAGTGTTTATGACAGAATCTGCCGTAC
AAGAAAGAGCGGCAGAGCAA

Product: acetyl-CoA carboxylase carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta 2; Acetyl-CoA carboxylase carboxyltransferase subunit beta 2

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTVKCNKCKEEINKEDLEKNYYICPLCGKLNRMPAKNRLQMLTEKFDVMFNDQEFTDPIDFPSYKEKYESAREKSGETEG
VVCGRGTIGGNDTCIFIMEPNFMMGSMGTVVGDRITALFEYATKNRLPVIGYTVSGGARMQEGALSLMQMAKVSAAAKRH
SDAGLLYVVCTTDPTMGGATASFAMLGDIIISEPGAMIGFAGKRVVEQVTGEVLPDNFQSAEFQLKNGFIDDIVPRQEQR
AYLANILAIHAETVSA

Sequences:

>Translated_256_residues
MTVKCNKCKEEINKEDLEKNYYICPLCGKLNRMPAKNRLQMLTEKFDVMFNDQEFTDPIDFPSYKEKYESAREKSGETEG
VVCGRGTIGGNDTCIFIMEPNFMMGSMGTVVGDRITALFEYATKNRLPVIGYTVSGGARMQEGALSLMQMAKVSAAAKRH
SDAGLLYVVCTTDPTMGGATASFAMLGDIIISEPGAMIGFAGKRVVEQVTGEVLPDNFQSAEFQLKNGFIDDIVPRQEQR
AYLANILAIHAETVSA
>Mature_255_residues
TVKCNKCKEEINKEDLEKNYYICPLCGKLNRMPAKNRLQMLTEKFDVMFNDQEFTDPIDFPSYKEKYESAREKSGETEGV
VCGRGTIGGNDTCIFIMEPNFMMGSMGTVVGDRITALFEYATKNRLPVIGYTVSGGARMQEGALSLMQMAKVSAAAKRHS
DAGLLYVVCTTDPTMGGATASFAMLGDIIISEPGAMIGFAGKRVVEQVTGEVLPDNFQSAEFQLKNGFIDDIVPRQEQRA
YLANILAIHAETVSA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=250, Percent_Identity=45.2, Blast_Score=209, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD2_EUBE2 (C4Z630)

Other databases:

- EMBL:   CP001106
- RefSeq:   YP_002935556.1
- GeneID:   7962626
- GenomeReviews:   CP001106_GR
- KEGG:   eel:EUBELI_20277
- OMA:   RAYLANI
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 28109; Mature: 27977

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKCNKCKEEINKEDLEKNYYICPLCGKLNRMPAKNRLQMLTEKFDVMFNDQEFTDPID
CCCCCHHHHHHCCHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCCC
FPSYKEKYESAREKSGETEGVVCGRGTIGGNDTCIFIMEPNFMMGSMGTVVGDRITALFE
CCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHH
YATKNRLPVIGYTVSGGARMQEGALSLMQMAKVSAAAKRHSDAGLLYVVCTTDPTMGGAT
HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCH
ASFAMLGDIIISEPGAMIGFAGKRVVEQVTGEVLPDNFQSAEFQLKNGFIDDIVPRQEQR
HHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHCCCCHHHH
AYLANILAIHAETVSA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVKCNKCKEEINKEDLEKNYYICPLCGKLNRMPAKNRLQMLTEKFDVMFNDQEFTDPID
CCCCHHHHHHCCHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCCC
FPSYKEKYESAREKSGETEGVVCGRGTIGGNDTCIFIMEPNFMMGSMGTVVGDRITALFE
CCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHH
YATKNRLPVIGYTVSGGARMQEGALSLMQMAKVSAAAKRHSDAGLLYVVCTTDPTMGGAT
HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCH
ASFAMLGDIIISEPGAMIGFAGKRVVEQVTGEVLPDNFQSAEFQLKNGFIDDIVPRQEQR
HHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHCCCCHHHH
AYLANILAIHAETVSA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA