Click here to switch to the map view.

The map label for this gene is ypnP [H]

Identifier: 238921963

GI number: 238921963

Start: 160553

End: 161887

Strand: Reverse

Name: ypnP [H]

Synonym: EUBELI_20198

Alternate gene names: 238921963

Gene position: 161887-160553 (Counterclockwise)

Preceding gene: 238921964

Following gene: 238921962

Centisome position: 25.83

GC content: 41.27

Gene sequence:

>1335_bases
ATGTCAAAGGATGAATATTTAATTACCGATGCGCCCCTTAAAGCACTGACTGTTTTTGCCATGCCCATGATTCTGGGCAG
TTTTTTCCAACAGGTATATAATATGGCTGACTCAATTATTGTCGGTCAGTTTGTCGGTTCATCTGCACTTGCGGCTGTCG
GAGCCTGTGCTGCTCTCACAAATGTATTTATTTGTGTGGCACTTGGCGCCGGGGTAGGTGCCGGGGTGCTTGTGAGCCGT
TATTTTGGTGCAAGAAATTATAGTAAAATGAAGACCATTGTATCAACATCATTAATCAGTTTCCTGATTCTAAGTATATT
ATTGGGAATCTTTGGTTTCGGGTTATCACATTCAATGATGAGTTTATTACAGACACCAGCTGATATACTGGATGAAGCAG
TACTGTATCTTCGTGTTTATTTTGTGGGATTTCCGTTTCTGTTTATGTACAACATTCTTTCAACAATGTTTACTTCAATC
GGTGAATCAAAGATTCCGTTGGTGCTTCTGATATTTTCTTCCATCTTAAATATTCTGATGGATCTTTGGATGGTTGCTGG
TTTAGGACTTGGCGTGTTTGGCGCAGCTCTTGCAACCCTGATTGCACAGGGTATTTCAGCAGTATTTTCATTTATAATTT
TCTTTTGCCGGATGCGCAGGTATAAAAGTCACTTTGAATGGTTTGACAGGAAGGAGTTACGTTCAATGCTTCAGATTGCC
GTACCATCAATTCTTCAGCAGTCCACAGTATCAATTGGCATGATGATAGTACAGGCAGTTGTAAATCCTTTTGGTACACA
GGCACTCGCAGGTTATGCTGCGACAATGAGAGTAGAAAATGTATTTGCTCTTATATTTGTATCCATTGGAAATGCAGTGT
CACCTTATGTTTCCCAGAATCTTGGCGCGAAGAAAATTGGGCGTATCAAAAAAGGATATCATGCTGCACTCGTGTTAGAT
ATATGTTTTGCAGTCCTTGCTTTCATAGTCATTGAGACACTGCATACACACATTTCTTCGCTGTTCCTTGGTAAAGATGG
AACAGCTTTGGCATATCAGGTGTCAGGGGATTACATGAAATGGTTAGGTTACTTTTTCATTTTCATGGGTATCAAGATGG
CAACGGATGGAGTCCTTCGTGGGCTGGGAATCATGCGGCCATTTCTTATAGCTAATATGGTTAACCTTGCAATCCGTCTG
TCAGTTGCTATGATTTGTGCACCGCGTTTTGGTATAGAGTTTGTCTGGCTTGCTGTACCAGCCGGCTGGTTTGCAAATTT
TCTGATTTCCTATGTGGCACTCAGAAAGTCATGGCCGGTTGAAAAAGTTGATTGA

Upstream 100 bases:

>100_bases
TTCCAGATAAGATTATTGATGAAATAAGTGATGCTGTGAATTATATCAGGGGGTATATGGGGAGAGAATAAAAACGAGAA
ATTCAAGGAGAAATAAGAGA

Downstream 100 bases:

>100_bases
TGAGCTCGTGAGCGTGCTTAATTGGCATGACGGCTAATGATGTTCAAAAGATTTTGAACCTGAAATAAAGATAACATGTT
TGACATAAAACCCGTTGAAT

Product: multidrug resistance protein, MATE family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSKDEYLITDAPLKALTVFAMPMILGSFFQQVYNMADSIIVGQFVGSSALAAVGACAALTNVFICVALGAGVGAGVLVSR
YFGARNYSKMKTIVSTSLISFLILSILLGIFGFGLSHSMMSLLQTPADILDEAVLYLRVYFVGFPFLFMYNILSTMFTSI
GESKIPLVLLIFSSILNILMDLWMVAGLGLGVFGAALATLIAQGISAVFSFIIFFCRMRRYKSHFEWFDRKELRSMLQIA
VPSILQQSTVSIGMMIVQAVVNPFGTQALAGYAATMRVENVFALIFVSIGNAVSPYVSQNLGAKKIGRIKKGYHAALVLD
ICFAVLAFIVIETLHTHISSLFLGKDGTALAYQVSGDYMKWLGYFFIFMGIKMATDGVLRGLGIMRPFLIANMVNLAIRL
SVAMICAPRFGIEFVWLAVPAGWFANFLISYVALRKSWPVEKVD

Sequences:

>Translated_444_residues
MSKDEYLITDAPLKALTVFAMPMILGSFFQQVYNMADSIIVGQFVGSSALAAVGACAALTNVFICVALGAGVGAGVLVSR
YFGARNYSKMKTIVSTSLISFLILSILLGIFGFGLSHSMMSLLQTPADILDEAVLYLRVYFVGFPFLFMYNILSTMFTSI
GESKIPLVLLIFSSILNILMDLWMVAGLGLGVFGAALATLIAQGISAVFSFIIFFCRMRRYKSHFEWFDRKELRSMLQIA
VPSILQQSTVSIGMMIVQAVVNPFGTQALAGYAATMRVENVFALIFVSIGNAVSPYVSQNLGAKKIGRIKKGYHAALVLD
ICFAVLAFIVIETLHTHISSLFLGKDGTALAYQVSGDYMKWLGYFFIFMGIKMATDGVLRGLGIMRPFLIANMVNLAIRL
SVAMICAPRFGIEFVWLAVPAGWFANFLISYVALRKSWPVEKVD
>Mature_443_residues
SKDEYLITDAPLKALTVFAMPMILGSFFQQVYNMADSIIVGQFVGSSALAAVGACAALTNVFICVALGAGVGAGVLVSRY
FGARNYSKMKTIVSTSLISFLILSILLGIFGFGLSHSMMSLLQTPADILDEAVLYLRVYFVGFPFLFMYNILSTMFTSIG
ESKIPLVLLIFSSILNILMDLWMVAGLGLGVFGAALATLIAQGISAVFSFIIFFCRMRRYKSHFEWFDRKELRSMLQIAV
PSILQQSTVSIGMMIVQAVVNPFGTQALAGYAATMRVENVFALIFVSIGNAVSPYVSQNLGAKKIGRIKKGYHAALVLDI
CFAVLAFIVIETLHTHISSLFLGKDGTALAYQVSGDYMKWLGYFFIFMGIKMATDGVLRGLGIMRPFLIANMVNLAIRLS
VAMICAPRFGIEFVWLAVPAGWFANFLISYVALRKSWPVEKVD

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48570; Mature: 48439

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDEYLITDAPLKALTVFAMPMILGSFFQQVYNMADSIIVGQFVGSSALAAVGACAALT
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
NVFICVALGAGVGAGVLVSRYFGARNYSKMKTIVSTSLISFLILSILLGIFGFGLSHSMM
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLQTPADILDEAVLYLRVYFVGFPFLFMYNILSTMFTSIGESKIPLVLLIFSSILNILM
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
DLWMVAGLGLGVFGAALATLIAQGISAVFSFIIFFCRMRRYKSHFEWFDRKELRSMLQIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VPSILQQSTVSIGMMIVQAVVNPFGTQALAGYAATMRVENVFALIFVSIGNAVSPYVSQN
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHHHC
LGAKKIGRIKKGYHAALVLDICFAVLAFIVIETLHTHISSLFLGKDGTALAYQVSGDYMK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHH
WLGYFFIFMGIKMATDGVLRGLGIMRPFLIANMVNLAIRLSVAMICAPRFGIEFVWLAVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHC
AGWFANFLISYVALRKSWPVEKVD
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKDEYLITDAPLKALTVFAMPMILGSFFQQVYNMADSIIVGQFVGSSALAAVGACAALT
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
NVFICVALGAGVGAGVLVSRYFGARNYSKMKTIVSTSLISFLILSILLGIFGFGLSHSMM
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLQTPADILDEAVLYLRVYFVGFPFLFMYNILSTMFTSIGESKIPLVLLIFSSILNILM
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
DLWMVAGLGLGVFGAALATLIAQGISAVFSFIIFFCRMRRYKSHFEWFDRKELRSMLQIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VPSILQQSTVSIGMMIVQAVVNPFGTQALAGYAATMRVENVFALIFVSIGNAVSPYVSQN
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHHHC
LGAKKIGRIKKGYHAALVLDICFAVLAFIVIETLHTHISSLFLGKDGTALAYQVSGDYMK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHH
WLGYFFIFMGIKMATDGVLRGLGIMRPFLIANMVNLAIRLSVAMICAPRFGIEFVWLAVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHC
AGWFANFLISYVALRKSWPVEKVD
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]