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The map label for this gene is btuC [H]

Identifier: 238921955

GI number: 238921955

Start: 153039

End: 154052

Strand: Reverse

Name: btuC [H]

Synonym: EUBELI_20189

Alternate gene names: 238921955

Gene position: 154052-153039 (Counterclockwise)

Preceding gene: 238921956

Following gene: 238921954

Centisome position: 24.58

GC content: 36.79

Gene sequence:

>1014_bases
ATGCAGATAAAACAGATACTCCGTTATCAGTTGGTTTATGTGCTGCTTGTGATATTACTTGTTGCAGCAGTCATATTCAA
TATTAATACAGGCAATATAAATATATCTCCCATAAGGATTTTCAGGATAATATTTCTGAAGGATTATGTTGGAACACCAG
AATATAATATTATCTGGAAAATACGATTACCACGATTATGTATGGCTGCTATTCTTGGCGGTGCATTGTCATTGTCGGGA
TTTTTATTACAGACATTTTTCAGAAATCCTATAGCAGGTCCGTTTGTGCTTGGTATTTCGTCAGGTGCCAAAATGTTTGT
TGCCATTACAATGATTTTCTTGCTGAAATATGTGTCAGGAATGCCATTATGGGCTCAGATTGCAGCAGCATTTATAGGTT
CACTTTTTGCAATGCTGTATGTATTACTTTTTGCCAATAAAGTAAAGAGCATGTCTATGCTTTTAGTTGTAGGAATTATG
ATAAGTTATATATGCTCTGCAATAACTGATTTATGTATTACATTTGCAAATGATTCAGATATTGCCAATCTTACCCACTG
GGCTATGGGCAGCTTTTCCGGAAGCTCATGGACTGCTGTAAAGCTTGCAGCTATAGTTGTTTTTCCAACATCATTCATTA
CTTTTTTATTTTCAAAACCAATTAATGCTTATCTGTTGGGAGAGGGATATGCACAGAGTATGGGAATTAATATCAGATTT
TTCAGGGTGTGTATAGTAATGCTGTCGAGTATGCTTTCTGCCTGTGTTACAGCACTTGCAGGCCCGATATCGTTTGTGGG
GATAGCAGTTCCGCATATTACAAGATTATCACTTAAAACAACAAAACCACTAGTTACGATTCCAGCGATTTTCCTGTGTG
GTTCAGTCTTTTGTATGTTCTGTGACCTTATTGCAAGAACAATATTTTCACCATCAGAACTGGCAATAGGAACAGTTACA
GCTGTATTTGGCGCACCAGTGGTTATCTGGCTTATGGTAAAGCAGAAAAAGTAA

Upstream 100 bases:

>100_bases
AAGTTAAAATAAAACTTATGTCTGAAAGTGACTGTCACATTAAGCAAATAGTACTTAATGAGGCAGTCATTTTGAGAATA
GAGATAAGAATGGAGAAAAA

Downstream 100 bases:

>100_bases
TATTGGATAAAAAGTGGAGAAATATATGGAACAGATATATGTGCAGACAGAGGATTTAAGCGTTGGATATCATGGAAAAG
TCCTTTTGTCAGATATAGCA

Product: iron complex transport system permease protein

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQIKQILRYQLVYVLLVILLVAAVIFNINTGNINISPIRIFRIIFLKDYVGTPEYNIIWKIRLPRLCMAAILGGALSLSG
FLLQTFFRNPIAGPFVLGISSGAKMFVAITMIFLLKYVSGMPLWAQIAAAFIGSLFAMLYVLLFANKVKSMSMLLVVGIM
ISYICSAITDLCITFANDSDIANLTHWAMGSFSGSSWTAVKLAAIVVFPTSFITFLFSKPINAYLLGEGYAQSMGINIRF
FRVCIVMLSSMLSACVTALAGPISFVGIAVPHITRLSLKTTKPLVTIPAIFLCGSVFCMFCDLIARTIFSPSELAIGTVT
AVFGAPVVIWLMVKQKK

Sequences:

>Translated_337_residues
MQIKQILRYQLVYVLLVILLVAAVIFNINTGNINISPIRIFRIIFLKDYVGTPEYNIIWKIRLPRLCMAAILGGALSLSG
FLLQTFFRNPIAGPFVLGISSGAKMFVAITMIFLLKYVSGMPLWAQIAAAFIGSLFAMLYVLLFANKVKSMSMLLVVGIM
ISYICSAITDLCITFANDSDIANLTHWAMGSFSGSSWTAVKLAAIVVFPTSFITFLFSKPINAYLLGEGYAQSMGINIRF
FRVCIVMLSSMLSACVTALAGPISFVGIAVPHITRLSLKTTKPLVTIPAIFLCGSVFCMFCDLIARTIFSPSELAIGTVT
AVFGAPVVIWLMVKQKK
>Mature_337_residues
MQIKQILRYQLVYVLLVILLVAAVIFNINTGNINISPIRIFRIIFLKDYVGTPEYNIIWKIRLPRLCMAAILGGALSLSG
FLLQTFFRNPIAGPFVLGISSGAKMFVAITMIFLLKYVSGMPLWAQIAAAFIGSLFAMLYVLLFANKVKSMSMLLVVGIM
ISYICSAITDLCITFANDSDIANLTHWAMGSFSGSSWTAVKLAAIVVFPTSFITFLFSKPINAYLLGEGYAQSMGINIRF
FRVCIVMLSSMLSACVTALAGPISFVGIAVPHITRLSLKTTKPLVTIPAIFLCGSVFCMFCDLIARTIFSPSELAIGTVT
AVFGAPVVIWLMVKQKK

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=36.2369337979094, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1790740, Length=317, Percent_Identity=27.4447949526814, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1790741, Length=294, Percent_Identity=29.2517006802721, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786805, Length=300, Percent_Identity=29.6666666666667, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786804, Length=334, Percent_Identity=26.6467065868263, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786347, Length=280, Percent_Identity=30.3571428571429, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36841; Mature: 36841

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKQILRYQLVYVLLVILLVAAVIFNINTGNINISPIRIFRIIFLKDYVGTPEYNIIWK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEE
IRLPRLCMAAILGGALSLSGFLLQTFFRNPIAGPFVLGISSGAKMFVAITMIFLLKYVSG
ECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCC
MPLWAQIAAAFIGSLFAMLYVLLFANKVKSMSMLLVVGIMISYICSAITDLCITFANDSD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IANLTHWAMGSFSGSSWTAVKLAAIVVFPTSFITFLFSKPINAYLLGEGYAQSMGINIRF
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCHHH
FRVCIVMLSSMLSACVTALAGPISFVGIAVPHITRLSLKTTKPLVTIPAIFLCGSVFCMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHH
CDLIARTIFSPSELAIGTVTAVFGAPVVIWLMVKQKK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MQIKQILRYQLVYVLLVILLVAAVIFNINTGNINISPIRIFRIIFLKDYVGTPEYNIIWK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEE
IRLPRLCMAAILGGALSLSGFLLQTFFRNPIAGPFVLGISSGAKMFVAITMIFLLKYVSG
ECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCC
MPLWAQIAAAFIGSLFAMLYVLLFANKVKSMSMLLVVGIMISYICSAITDLCITFANDSD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IANLTHWAMGSFSGSSWTAVKLAAIVVFPTSFITFLFSKPINAYLLGEGYAQSMGINIRF
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCHHH
FRVCIVMLSSMLSACVTALAGPISFVGIAVPHITRLSLKTTKPLVTIPAIFLCGSVFCMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHH
CDLIARTIFSPSELAIGTVTAVFGAPVVIWLMVKQKK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA