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The map label for this gene is cbiH [H]

Identifier: 238921949

GI number: 238921949

Start: 147562

End: 148281

Strand: Reverse

Name: cbiH [H]

Synonym: EUBELI_20183

Alternate gene names: 238921949

Gene position: 148281-147562 (Counterclockwise)

Preceding gene: 238921950

Following gene: 238921948

Centisome position: 23.66

GC content: 40.42

Gene sequence:

>720_bases
ATGCTTAAGATAGTTGGTTTTGGAAGTGGTGCAAAAGATAATATGACACTGGAAGCGTCAGCTGCAATATCGTCAGCACA
GTTAATAGTTGGCTATAATACTTATGTTGATATATTGAAGCAGTATTTTCCAGATAAAGAATATTATTCAACTAATATGA
TGCAGGAAAAGGAGCGTTGTCAGTATGCCATAGACATGGCAAATGAAGGCAGGGATGTAGTACTTGTATGCAGTGGAGAC
AGTGGTGTATATGGCATGGCGAGTCTGGTATATGAACTTGCAGATGAAGGAACTGATATTAAGGTAATATCAGGTGTCAC
AGCCGCCAATAGTGGTGCTGCCTGTCTCGGAGCACCTTTGTCACATGATTTTGCGGTTATAAGCTTAAGTGACTGTATGA
CTCCGTGGGAACTGATAAAGAAAAGAATCAGGGCAATGGCTGAAAGCGATATGGTAATGTGCATATATAATCCTTCAAGC
CGTAGGAGAGCAGGATATTTAAAAGAAGCCTGTGACATTGTAATGGAAGTACAGCCGGCTGATACAGTATGTGGCTATGT
AAGGAATATAGGCAGGGATAATGAGACAGCCGGGGTTCTTACATTAAAGGAGCTGGCTGATTTCAAAGCAGATATGTTCA
CGACAGTTTATATTGGAAACAGCCATACTAAGATTATTAATGGAAAGATGGTTACACCGAGAGGATATAAGGTTGTATGA

Upstream 100 bases:

>100_bases
ATGTGCAGCATCGGGTGGAGGCAGAAAGCTTGCAGGAAAAACGGCAGATAACGGAATAACTGTTGCGGTATATAAAATGG
TATAGATTAAGGAGTATGAT

Downstream 100 bases:

>100_bases
AAAAGACAATAATGCTTTTTGCCGGGACAACGGAAGGCCGCAGAATATGTGAATTTCTTGCAGTTAAAAAATGTATTACC
CATGTGTATGTAACTACTGA

Product: hypothetical protein

Products: S-adenosyl-L-homocysteine; Precorrin 4

Alternate protein names: Cobalt-precorrin-3 methylase; Cobalt-precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLKIVGFGSGAKDNMTLEASAAISSAQLIVGYNTYVDILKQYFPDKEYYSTNMMQEKERCQYAIDMANEGRDVVLVCSGD
SGVYGMASLVYELADEGTDIKVISGVTAANSGAACLGAPLSHDFAVISLSDCMTPWELIKKRIRAMAESDMVMCIYNPSS
RRRAGYLKEACDIVMEVQPADTVCGYVRNIGRDNETAGVLTLKELADFKADMFTTVYIGNSHTKIINGKMVTPRGYKVV

Sequences:

>Translated_239_residues
MLKIVGFGSGAKDNMTLEASAAISSAQLIVGYNTYVDILKQYFPDKEYYSTNMMQEKERCQYAIDMANEGRDVVLVCSGD
SGVYGMASLVYELADEGTDIKVISGVTAANSGAACLGAPLSHDFAVISLSDCMTPWELIKKRIRAMAESDMVMCIYNPSS
RRRAGYLKEACDIVMEVQPADTVCGYVRNIGRDNETAGVLTLKELADFKADMFTTVYIGNSHTKIINGKMVTPRGYKVV
>Mature_239_residues
MLKIVGFGSGAKDNMTLEASAAISSAQLIVGYNTYVDILKQYFPDKEYYSTNMMQEKERCQYAIDMANEGRDVVLVCSGD
SGVYGMASLVYELADEGTDIKVISGVTAANSGAACLGAPLSHDFAVISLSDCMTPWELIKKRIRAMAESDMVMCIYNPSS
RRRAGYLKEACDIVMEVQPADTVCGYVRNIGRDNETAGVLTLKELADFKADMFTTVYIGNSHTKIINGKMVTPRGYKVV

Specific function: Methyltransferase that catalyzes the methylation of C-17 in cobalt-precorrin-3B to form cobalt-precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: 2.1.1.131

Molecular weight: Translated: 26107; Mature: 26107

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIVGFGSGAKDNMTLEASAAISSAQLIVGYNTYVDILKQYFPDKEYYSTNMMQEKERC
CEEEEECCCCCCCCEEEEEHHCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QYAIDMANEGRDVVLVCSGDSGVYGMASLVYELADEGTDIKVISGVTAANSGAACLGAPL
HEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCEECCCCCEEECCCC
SHDFAVISLSDCMTPWELIKKRIRAMAESDMVMCIYNPSSRRRAGYLKEACDIVMEVQPA
CCCEEEEEHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHEEECCCH
DTVCGYVRNIGRDNETAGVLTLKELADFKADMFTTVYIGNSHTKIINGKMVTPRGYKVV
HHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCEEEEEEECCCCEEEEECEEECCCCCEEC
>Mature Secondary Structure
MLKIVGFGSGAKDNMTLEASAAISSAQLIVGYNTYVDILKQYFPDKEYYSTNMMQEKERC
CEEEEECCCCCCCCEEEEEHHCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QYAIDMANEGRDVVLVCSGDSGVYGMASLVYELADEGTDIKVISGVTAANSGAACLGAPL
HEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCEECCCCCEEECCCC
SHDFAVISLSDCMTPWELIKKRIRAMAESDMVMCIYNPSSRRRAGYLKEACDIVMEVQPA
CCCEEEEEHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHEEECCCH
DTVCGYVRNIGRDNETAGVLTLKELADFKADMFTTVYIGNSHTKIINGKMVTPRGYKVV
HHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCEEEEEEECCCCEEEEECEEECCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 3B

Specific reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin-4

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]