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The map label for this gene is cbiJ [H]

Identifier: 238921948

GI number: 238921948

Start: 146774

End: 147565

Strand: Reverse

Name: cbiJ [H]

Synonym: EUBELI_20182

Alternate gene names: 238921948

Gene position: 147565-146774 (Counterclockwise)

Preceding gene: 238921949

Following gene: 238921947

Centisome position: 23.54

GC content: 37.63

Gene sequence:

>792_bases
ATGAAAAAGACAATAATGCTTTTTGCCGGGACAACGGAAGGCCGCAGAATATGTGAATTTCTTGCAGTTAAAAAATGTAT
TACCCATGTGTATGTAACTACTGAGTATGGAAAAGAACTGCTTCCTGGGCAGAATAATGTGCATATACATGTCGGGAAAA
TGGATGAGAAACAGATGTCTGATGAGATAAAGGCAATCCATCCTGACATAGTTATTGATGCAACACATCCGTATGCCACA
CAGGTTACCCACAATATAAAAGAGGCATGTGACAGCAGACACATTTTTTATGTCAGGGTATTAAGAGAAGAGAATATAGA
AAAAGCTGGTAATAATGCAGACAATATCATATATACTGAAACAATGAAGGATGCAGTCAGGCTGCTGAATGAAGACAGAT
ATATTCATAAAAACGTTCTTATGACGACAGGAAGCAAGAACATACCTGAGTATGTCCATATTAAGGATTTTAAGGACAGG
CTGTATCTTCGCCTTCTGCCTAATCCACAGATGATGGAAAGTGCAATACAGGCAGGGATTATGCCGGCACATTTAATTGG
AATGCAGGGACCATTTTCACAGGAATTAAACGAAGCAGTAATAAGGCAGTTTAATATCGGGGTACTTGTTACAAAAGAAT
CAGGAAATAACGGTGGATATGAAGAAAAAATATCTGCTACACTAAATACAGGAACTGACTGCATTGTAATAAGGCGGCCA
TTGGAAAATGGTGGTAAGAATCTTTCAGAAATTATAGCGTATCTTGAAGAAAATATTGATTCACAGTGTTAA

Upstream 100 bases:

>100_bases
CTGATTTCAAAGCAGATATGTTCACGACAGTTTATATTGGAAACAGCCATACTAAGATTATTAATGGAAAGATGGTTACA
CCGAGAGGATATAAGGTTGT

Downstream 100 bases:

>100_bases
CAGGTTAAGATGGAGTGAGTAATGAAAAGGGTAATTATAGCTGGAATGGGACCGGGCAGTAAAAGCTGCATTACAGAGGA
AGTAAAAGCTGCAATTGATA

Product: precorrin-6X reductase

Products: Precorrin 6A; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKKTIMLFAGTTEGRRICEFLAVKKCITHVYVTTEYGKELLPGQNNVHIHVGKMDEKQMSDEIKAIHPDIVIDATHPYAT
QVTHNIKEACDSRHIFYVRVLREENIEKAGNNADNIIYTETMKDAVRLLNEDRYIHKNVLMTTGSKNIPEYVHIKDFKDR
LYLRLLPNPQMMESAIQAGIMPAHLIGMQGPFSQELNEAVIRQFNIGVLVTKESGNNGGYEEKISATLNTGTDCIVIRRP
LENGGKNLSEIIAYLEENIDSQC

Sequences:

>Translated_263_residues
MKKTIMLFAGTTEGRRICEFLAVKKCITHVYVTTEYGKELLPGQNNVHIHVGKMDEKQMSDEIKAIHPDIVIDATHPYAT
QVTHNIKEACDSRHIFYVRVLREENIEKAGNNADNIIYTETMKDAVRLLNEDRYIHKNVLMTTGSKNIPEYVHIKDFKDR
LYLRLLPNPQMMESAIQAGIMPAHLIGMQGPFSQELNEAVIRQFNIGVLVTKESGNNGGYEEKISATLNTGTDCIVIRRP
LENGGKNLSEIIAYLEENIDSQC
>Mature_263_residues
MKKTIMLFAGTTEGRRICEFLAVKKCITHVYVTTEYGKELLPGQNNVHIHVGKMDEKQMSDEIKAIHPDIVIDATHPYAT
QVTHNIKEACDSRHIFYVRVLREENIEKAGNNADNIIYTETMKDAVRLLNEDRYIHKNVLMTTGSKNIPEYVHIKDFKDR
LYLRLLPNPQMMESAIQAGIMPAHLIGMQGPFSQELNEAVIRQFNIGVLVTKESGNNGGYEEKISATLNTGTDCIVIRRP
LENGGKNLSEIIAYLEENIDSQC

Specific function: Catalyzes the reduction of the macrocycle of cobalt- precorrin-6X into cobalt-precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: 1.3.1.54

Molecular weight: Translated: 29790; Mature: 29790

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIMLFAGTTEGRRICEFLAVKKCITHVYVTTEYGKELLPGQNNVHIHVGKMDEKQMS
CCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEHHCHHHCCCCCCEEEEEECCCHHHHH
DEIKAIHPDIVIDATHPYATQVTHNIKEACDSRHIFYVRVLREENIEKAGNNADNIIYTE
HHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHCCCCCCCEEEEH
TMKDAVRLLNEDRYIHKNVLMTTGSKNIPEYVHIKDFKDRLYLRLLPNPQMMESAIQAGI
HHHHHHHHHCCCCEEECEEEEECCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHCC
MPAHLIGMQGPFSQELNEAVIRQFNIGVLVTKESGNNGGYEEKISATLNTGTDCIVIRRP
CHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHEEEEECCCCCEEEEECC
LENGGKNLSEIIAYLEENIDSQC
CCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKTIMLFAGTTEGRRICEFLAVKKCITHVYVTTEYGKELLPGQNNVHIHVGKMDEKQMS
CCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEHHCHHHCCCCCCEEEEEECCCHHHHH
DEIKAIHPDIVIDATHPYATQVTHNIKEACDSRHIFYVRVLREENIEKAGNNADNIIYTE
HHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHCCCCCCCEEEEH
TMKDAVRLLNEDRYIHKNVLMTTGSKNIPEYVHIKDFKDRLYLRLLPNPQMMESAIQAGI
HHHHHHHHHCCCCEEECEEEEECCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHCC
MPAHLIGMQGPFSQELNEAVIRQFNIGVLVTKESGNNGGYEEKISATLNTGTDCIVIRRP
CHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHEEEEECCCCCEEEEECC
LENGGKNLSEIIAYLEENIDSQC
CCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 6B; NADP+

Specific reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]