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The map label for this gene is arsR [H]

Identifier: 238921873

GI number: 238921873

Start: 81727

End: 81999

Strand: Reverse

Name: arsR [H]

Synonym: EUBELI_20106

Alternate gene names: 238921873

Gene position: 81999-81727 (Counterclockwise)

Preceding gene: 238921874

Following gene: 238921872

Centisome position: 13.08

GC content: 35.16

Gene sequence:

>273_bases
ATGAATGCTGAAAAAGTTGCATTGATTTGCAAAGCACTTGGAGATACAAACAGGTTGGAGATAGTTCAGATACTGTCCGA
TGGCGAGAAATGTGGCTGTAAGATATTAGAAAAGTTTGAAATTACACAGCCTACACTATCACATCATATGAAAATACTTA
CAGCATGTGGTCTTGTGAATGATCGAAAAGAAGGAAAATGGCATCATTATTCTTTGAACTGTGAAACACTGATGAATTAC
AAGCATTTTATAGAATGCCTTACCTGTGTTTAA

Upstream 100 bases:

>100_bases
GGCTATGCAGTAATGTGTAGCCTTTTTGAGTATCAATACATTGACATATATCTATGTATATGATATAACATAGACAAACA
TCTATGTGAGGTGAATAATT

Downstream 100 bases:

>100_bases
TGCAGGGAAAAAGTTTGCTGAAATAAATTTAAGGAGATTACAATGACGATACAGGATAAAGCAGAACTTATAATTAAAGA
TATTAAATTAGAAAAAGGAA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MNAEKVALICKALGDTNRLEIVQILSDGEKCGCKILEKFEITQPTLSHHMKILTACGLVNDRKEGKWHHYSLNCETLMNY
KHFIECLTCV

Sequences:

>Translated_90_residues
MNAEKVALICKALGDTNRLEIVQILSDGEKCGCKILEKFEITQPTLSHHMKILTACGLVNDRKEGKWHHYSLNCETLMNY
KHFIECLTCV
>Mature_90_residues
MNAEKVALICKALGDTNRLEIVQILSDGEKCGCKILEKFEITQPTLSHHMKILTACGLVNDRKEGKWHHYSLNCETLMNY
KHFIECLTCV

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=64, Percent_Identity=45.3125, Blast_Score=58, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 10265; Mature: 10265

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
11.1 %Cys+Met (Translated Protein)
7.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
11.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEKVALICKALGDTNRLEIVQILSDGEKCGCKILEKFEITQPTLSHHMKILTACGLVN
CCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
DRKEGKWHHYSLNCETLMNYKHFIECLTCV
CCCCCCEEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAEKVALICKALGDTNRLEIVQILSDGEKCGCKILEKFEITQPTLSHHMKILTACGLVN
CCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
DRKEGKWHHYSLNCETLMNYKHFIECLTCV
CCCCCCEEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1534327 [H]