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The map label for this gene is ycbM [H]

Identifier: 238921798

GI number: 238921798

Start: 16495

End: 17394

Strand: Reverse

Name: ycbM [H]

Synonym: EUBELI_20031

Alternate gene names: 238921798

Gene position: 17394-16495 (Counterclockwise)

Preceding gene: 238921799

Following gene: 238921797

Centisome position: 2.78

GC content: 37.0

Gene sequence:

>900_bases
ATGAGGATTATTATTGGAATATTAGCAGTAATAATTATTATACAGGCATTTATTATGTGGAAATACCAGCGGCAGATTAA
GGACATCTGCCGCCAGTTGTCGTTTCTTATGGAACACGATAGTAACAAGCTGATTCAACGTGAAATAGATATGGGGGGAA
TAGGTGAGCTTTCAGATAAATTGAATGAGCTTCTTGACCTGCGTAAAAAAGAAAGAAATGAGTACAGAAAAAAAGAAGAG
CTGATTGCAGATACATATACTAATCTTTCACACGATATAAGGACACCGCTTACATCGCTGGATGGGTATTTCCAGCTTAT
AGAGGAATGTGACAATATAGATGACCAGAGGAGATATCTTGATATAATCAGAGAAAGGCTTAACAGCCTTAATGAAATGC
TGGAGGAGCTTTTTACATTCACTAAGCTGAAAAATGATTCATATAAGCTGGAGCTTACGGATTGTTGTATGAACAGAATA
TTAAAAGAAGCTGTATTTTCTTATTATGATGAATGGAAGAAGCAGGGCATCTGCCCGGATATTAGTATTACTGAGGAAAT
GCTGTATATATCAGGTAATAAGCAGGGCTTAAGGAGAGTTATACAGAATGTCATAAAAAATGGTCTTGATCATGGGGAAA
AGAATATAAGTATCAAGCTTACCCGTGAGGACAATCACGCCTTGCTTAAAATTAGTAATTATACGGAACATCCTGAAAAT
ATTGACTTAAGCCATGTGTTCGAGCGTTTTTATAAAGCAGATGTGGCAAGAGGCAGAGCCTCAACCGGACTGGGGTTATC
TATTGCAAAAGAGCTTGTGGGGCGTATGAATGGAGATATAAGTGCAAGAATACAGGGGAATGATTTCATTATTGAGATAA
AAGTTTTGCTTGTGGTATAA

Upstream 100 bases:

>100_bases
CAGGGAGGATGTTGTTAGTTCAATGTGTGTGGCAGCTATATTTATTATTATAATGCTGTCATTAAGCAGTTATATTTTTC
AGAAAAGGGATATTTAGAGA

Downstream 100 bases:

>100_bases
CATGCATAGGCTGAAAACCAGGAGGATTACATCATGGAACGAGTAGTACAATTTTTAAAAGAAGGACAATGACATGGTAA
GAAAAATTATGCGGGATCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRIIIGILAVIIIIQAFIMWKYQRQIKDICRQLSFLMEHDSNKLIQREIDMGGIGELSDKLNELLDLRKKERNEYRKKEE
LIADTYTNLSHDIRTPLTSLDGYFQLIEECDNIDDQRRYLDIIRERLNSLNEMLEELFTFTKLKNDSYKLELTDCCMNRI
LKEAVFSYYDEWKKQGICPDISITEEMLYISGNKQGLRRVIQNVIKNGLDHGEKNISIKLTREDNHALLKISNYTEHPEN
IDLSHVFERFYKADVARGRASTGLGLSIAKELVGRMNGDISARIQGNDFIIEIKVLLVV

Sequences:

>Translated_299_residues
MRIIIGILAVIIIIQAFIMWKYQRQIKDICRQLSFLMEHDSNKLIQREIDMGGIGELSDKLNELLDLRKKERNEYRKKEE
LIADTYTNLSHDIRTPLTSLDGYFQLIEECDNIDDQRRYLDIIRERLNSLNEMLEELFTFTKLKNDSYKLELTDCCMNRI
LKEAVFSYYDEWKKQGICPDISITEEMLYISGNKQGLRRVIQNVIKNGLDHGEKNISIKLTREDNHALLKISNYTEHPEN
IDLSHVFERFYKADVARGRASTGLGLSIAKELVGRMNGDISARIQGNDFIIEIKVLLVV
>Mature_299_residues
MRIIIGILAVIIIIQAFIMWKYQRQIKDICRQLSFLMEHDSNKLIQREIDMGGIGELSDKLNELLDLRKKERNEYRKKEE
LIADTYTNLSHDIRTPLTSLDGYFQLIEECDNIDDQRRYLDIIRERLNSLNEMLEELFTFTKLKNDSYKLELTDCCMNRI
LKEAVFSYYDEWKKQGICPDISITEEMLYISGNKQGLRRVIQNVIKNGLDHGEKNISIKLTREDNHALLKISNYTEHPEN
IDLSHVFERFYKADVARGRASTGLGLSIAKELVGRMNGDISARIQGNDFIIEIKVLLVV

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=29.1845493562232, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=279, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=24.901185770751, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=24.6913580246914, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 34910; Mature: 34910

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIIGILAVIIIIQAFIMWKYQRQIKDICRQLSFLMEHDSNKLIQREIDMGGIGELSDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHH
LNELLDLRKKERNEYRKKEELIADTYTNLSHDIRTPLTSLDGYFQLIEECDNIDDQRRYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
DIIRERLNSLNEMLEELFTFTKLKNDSYKLELTDCCMNRILKEAVFSYYDEWKKQGICPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ISITEEMLYISGNKQGLRRVIQNVIKNGLDHGEKNISIKLTREDNHALLKISNYTEHPEN
CCHHHHHHEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCCCC
IDLSHVFERFYKADVARGRASTGLGLSIAKELVGRMNGDISARIQGNDFIIEIKVLLVV
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEEEEEEEEC
>Mature Secondary Structure
MRIIIGILAVIIIIQAFIMWKYQRQIKDICRQLSFLMEHDSNKLIQREIDMGGIGELSDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHH
LNELLDLRKKERNEYRKKEELIADTYTNLSHDIRTPLTSLDGYFQLIEECDNIDDQRRYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
DIIRERLNSLNEMLEELFTFTKLKNDSYKLELTDCCMNRILKEAVFSYYDEWKKQGICPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ISITEEMLYISGNKQGLRRVIQNVIKNGLDHGEKNISIKLTREDNHALLKISNYTEHPEN
CCHHHHHHEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCCCC
IDLSHVFERFYKADVARGRASTGLGLSIAKELVGRMNGDISARIQGNDFIIEIKVLLVV
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]