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The map label for this gene is aphA [H]

Identifier: 238921672

GI number: 238921672

Start: 3713440

End: 3714165

Strand: Reverse

Name: aphA [H]

Synonym: NT01EI_3833

Alternate gene names: 238921672

Gene position: 3714165-3713440 (Counterclockwise)

Preceding gene: 238921675

Following gene: 238921671

Centisome position: 97.43

GC content: 46.56

Gene sequence:

>726_bases
ATGTTTATAACCACAAAAAAATCACTGATTGCATTAGTCCTTGCTACAGCCGGTCTGATTTCCTCTCCAGTTTCTTTTGC
TACTGAGACAGGCGCACAGCCGAATCTGGGCGCTACGCTGACGCAGTTAACGCAGCAATATCCGATTCACTGGATCTCTA
TTGAGCAGGTCGCTGAAAGTCTTAAAGGGAAGGCACCGATTAGCGTTGGTTTTGATATCGACGATACACTGTTATTTTCC
AGCCCAGCATTTTTTTATGGGAAACAAAAATTTTCACCTGACAGCAATGCGTTTTTGAAAAACCAGAAGTTTTGGGATGC
AGTCAGCAGCAGCGGTTGGGATCGCTTCTCGATCCCCAAAGATTCTGGCCGGGCGCTGATGGAACTGCATTTAAAACGCG
GTGATCATGTCTATTTCATCACCGGACGTCCGATGCCGTCTAATGGTAAAGAGGATTTGACTCAAACGCTGAAAGACGAT
TTCAAAATTCCGGATAATCAGCTGAATAAGGTGATTTTTGCCGGGACCAAACAAGATGCCAAAGTTGAATATATGCAGAA
GTACCATATCACCATCTTCTACGGTGATTCTGACAATGATATTCAGGACGCCCGCAAGGCTGGCGCTGAAGGGATCCGGG
TGCTGCGCCCGCTGAACTCCACCAATAAGCCGATGCCGAAGAACGGGGCATTTGGTGAAAAAGTCATCGTGAATTCCCAG
TACTGA

Upstream 100 bases:

>100_bases
TAAACATGGATCATGATCACATTAATCACGCTGTTTGAGTCGATATAGTTTTATATATACAAAATGGACTCCCTCCATGC
AAAATTAAGAGATTATCGCT

Downstream 100 bases:

>100_bases
TCGCGTTAATAGACAAGAAGGCATTGATGAAACATACGCTAAAACTGAGCCTGGCCGCGGCGGTGATGGTATTGGCCGGT
TGCGCCGCCCACCCGCAGAG

Product: acid phosphatase/phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MFITTKKSLIALVLATAGLISSPVSFATETGAQPNLGATLTQLTQQYPIHWISIEQVAESLKGKAPISVGFDIDDTLLFS
SPAFFYGKQKFSPDSNAFLKNQKFWDAVSSSGWDRFSIPKDSGRALMELHLKRGDHVYFITGRPMPSNGKEDLTQTLKDD
FKIPDNQLNKVIFAGTKQDAKVEYMQKYHITIFYGDSDNDIQDARKAGAEGIRVLRPLNSTNKPMPKNGAFGEKVIVNSQ
Y

Sequences:

>Translated_241_residues
MFITTKKSLIALVLATAGLISSPVSFATETGAQPNLGATLTQLTQQYPIHWISIEQVAESLKGKAPISVGFDIDDTLLFS
SPAFFYGKQKFSPDSNAFLKNQKFWDAVSSSGWDRFSIPKDSGRALMELHLKRGDHVYFITGRPMPSNGKEDLTQTLKDD
FKIPDNQLNKVIFAGTKQDAKVEYMQKYHITIFYGDSDNDIQDARKAGAEGIRVLRPLNSTNKPMPKNGAFGEKVIVNSQ
Y
>Mature_241_residues
MFITTKKSLIALVLATAGLISSPVSFATETGAQPNLGATLTQLTQQYPIHWISIEQVAESLKGKAPISVGFDIDDTLLFS
SPAFFYGKQKFSPDSNAFLKNQKFWDAVSSSGWDRFSIPKDSGRALMELHLKRGDHVYFITGRPMPSNGKEDLTQTLKDD
FKIPDNQLNKVIFAGTKQDAKVEYMQKYHITIFYGDSDNDIQDARKAGAEGIRVLRPLNSTNKPMPKNGAFGEKVIVNSQ
Y

Specific function: Dephosphorylates several organic phosphomonoesters and catalyzes the transfer of low-energy phosphate groups from phosphomonoesters to hydroxyl groups of various organic compounds. Might function as a broad spectrum dephosphorylating enzyme able to scaven

COG id: COG3700

COG function: function code R; Acid phosphatase (class B)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class B bacterial acid phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI2367341, Length=241, Percent_Identity=50.6224066390041, Blast_Score=241, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005519
- InterPro:   IPR023214
- InterPro:   IPR010025 [H]

Pfam domain/function: PF03767 Acid_phosphat_B [H]

EC number: =3.1.3.2 [H]

Molecular weight: Translated: 26761; Mature: 26761

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFITTKKSLIALVLATAGLISSPVSFATETGAQPNLGATLTQLTQQYPIHWISIEQVAES
CEEECHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEHHHHHHH
LKGKAPISVGFDIDDTLLFSSPAFFYGKQKFSPDSNAFLKNQKFWDAVSSSGWDRFSIPK
HCCCCCEEECCCCCCCEEECCCHHEECCCCCCCCCCCHHCCCHHHHHHHCCCCCCCCCCC
DSGRALMELHLKRGDHVYFITGRPMPSNGKEDLTQTLKDDFKIPDNQLNKVIFAGTKQDA
CCCCCEEHHEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHCEEEEECCCCCC
KVEYMQKYHITIFYGDSDNDIQDARKAGAEGIRVLRPLNSTNKPMPKNGAFGEKVIVNSQ
HHEEEEEEEEEEEECCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECC
Y
C
>Mature Secondary Structure
MFITTKKSLIALVLATAGLISSPVSFATETGAQPNLGATLTQLTQQYPIHWISIEQVAES
CEEECHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEHHHHHHH
LKGKAPISVGFDIDDTLLFSSPAFFYGKQKFSPDSNAFLKNQKFWDAVSSSGWDRFSIPK
HCCCCCEEECCCCCCCEEECCCHHEECCCCCCCCCCCHHCCCHHHHHHHCCCCCCCCCCC
DSGRALMELHLKRGDHVYFITGRPMPSNGKEDLTQTLKDDFKIPDNQLNKVIFAGTKQDA
CCCCCEEHHEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHCEEEEECCCCCC
KVEYMQKYHITIFYGDSDNDIQDARKAGAEGIRVLRPLNSTNKPMPKNGAFGEKVIVNSQ
HHEEEEEEEEEEEECCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10564784; 11677608; 12644504 [H]