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The map label for this gene is gpsA

Identifier: 238921659

GI number: 238921659

Start: 3696002

End: 3697018

Strand: Reverse

Name: gpsA

Synonym: NT01EI_3815

Alternate gene names: 238921659

Gene position: 3697018-3696002 (Counterclockwise)

Preceding gene: 238921660

Following gene: 238921658

Centisome position: 96.98

GC content: 60.57

Gene sequence:

>1017_bases
ATGACAACGCCTGTCGCTTCCATGGCCGTTATCGGTGCCGGCTCTTACGGCACCGCATTGGCCATTACGCTGGCCCGTAA
CGGGCACCCGGTGGTGCTGTGGGGGCACGATCCAGCGCATATCGCTGCGCTGGAGGCCGCGCGCTGCAATCAGGCCTTTT
TGCCGGATGTCCGTTTTCCTGACACGCTGTCGCTGGAGTCGGATTTATCCCGTACATTGTCGGCCAGCCGCGATGTCCTC
GTGGTCGTGCCGAGCCACGTGTTTGGTGACGTATTGCGTCAGCTCCGCCCCCACCTGCGGCCAGATGCACGGTTGGTGTG
GGCAACCAAGGGACTGGAGGCGGAAACCGGGCGTTTATTGCAGGATGTAGCGTGTGAAGCGCTGGGGCCGGATATTCCGC
TGGCAGTGATCTCTGGGCCGACCTTTGCCAAAGAGCTAGCGGCGGGGCTGCCGACGGCGATCGCCGTGGCCTCTCAGGAT
GCGGCGTTTGCCGAGGTGCTACAGCAGCTACTGCACTGCGGCAAGAGTTTTCGAGTCTATCGCAACCCGGACTTCATCGG
TGTACAGCTGGGCGGTGCGGTCAAAAACGTTATCGCTATCGGCGCTGGTATGTCGGACGGCATCGGCTTTGGTGCTAATG
CCCGTACTGCCCTGATCACCCGAGGTCTTGCAGAAATGAGTCGGCTAGGGGTTGCCCTTGGTGCCGATCCTGCGACCTTT
ATGGGCATGGCCGGTCTTGGCGATCTGGTGCTGACCTGTACTGATAATCAGTCGCGCAACCGCCGCTTTGGCATTATGCT
GGGGCAGGGGATGGGCGTTGATGAGGCTCAGGTGCAGATAGGCCAGGTGGTCGAGGGTTACCGTAATACCAAAGAGGTGA
TGTCACTGGCACAGCGCTATGGCGTGGAGATGCCGATCACTGAGCAGATCTACCAGGTGCTGTATTGTCATAAAGACGTT
CGTGAGGCGGCGCTCTCGTTGTTGGGGCGCGCCAGTAGGGACGAAAACGCCCGGTGA

Upstream 100 bases:

>100_bases
GTACCTTCCCGCAGCTGAACCTGGCACCGGTTAACTTTGACGCGCTGTTCATGAGCTATCTGCAGCAGCAGGCCGGCGAA
GAGCCGACTCAGGAAGCGTA

Downstream 100 bases:

>100_bases
TGTATTGGTGGGTATTTGCCGGGCCGGCGGATACCCACTCTTTCTCCTCAGGGTGTGAGTCTCTCGGGATAATCATCACT
CTCCCCTTGACCGGGCGCAG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTTPVASMAVIGAGSYGTALAITLARNGHPVVLWGHDPAHIAALEAARCNQAFLPDVRFPDTLSLESDLSRTLSASRDVL
VVVPSHVFGDVLRQLRPHLRPDARLVWATKGLEAETGRLLQDVACEALGPDIPLAVISGPTFAKELAAGLPTAIAVASQD
AAFAEVLQQLLHCGKSFRVYRNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGVALGADPATF
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGMGVDEAQVQIGQVVEGYRNTKEVMSLAQRYGVEMPITEQIYQVLYCHKDV
REAALSLLGRASRDENAR

Sequences:

>Translated_338_residues
MTTPVASMAVIGAGSYGTALAITLARNGHPVVLWGHDPAHIAALEAARCNQAFLPDVRFPDTLSLESDLSRTLSASRDVL
VVVPSHVFGDVLRQLRPHLRPDARLVWATKGLEAETGRLLQDVACEALGPDIPLAVISGPTFAKELAAGLPTAIAVASQD
AAFAEVLQQLLHCGKSFRVYRNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGVALGADPATF
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGMGVDEAQVQIGQVVEGYRNTKEVMSLAQRYGVEMPITEQIYQVLYCHKDV
REAALSLLGRASRDENAR
>Mature_337_residues
TTPVASMAVIGAGSYGTALAITLARNGHPVVLWGHDPAHIAALEAARCNQAFLPDVRFPDTLSLESDLSRTLSASRDVLV
VVPSHVFGDVLRQLRPHLRPDARLVWATKGLEAETGRLLQDVACEALGPDIPLAVISGPTFAKELAAGLPTAIAVASQDA
AFAEVLQQLLHCGKSFRVYRNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGVALGADPATFM
GMAGLGDLVLTCTDNQSRNRRFGIMLGQGMGVDEAQVQIGQVVEGYRNTKEVMSLAQRYGVEMPITEQIYQVLYCHKDVR
EAALSLLGRASRDENAR

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=333, Percent_Identity=27.9279279279279, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI24307999, Length=340, Percent_Identity=25.8823529411765, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1790037, Length=337, Percent_Identity=83.6795252225519, Blast_Score=573, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17507425, Length=357, Percent_Identity=24.6498599439776, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32564399, Length=355, Percent_Identity=25.0704225352113, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=364, Percent_Identity=24.4505494505494, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210136, Length=354, Percent_Identity=24.2937853107345, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193210134, Length=202, Percent_Identity=28.7128712871287, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324513, Length=341, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320181, Length=343, Percent_Identity=27.6967930029155, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17136202, Length=331, Percent_Identity=25.6797583081571, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136200, Length=331, Percent_Identity=25.6797583081571, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136204, Length=331, Percent_Identity=25.6797583081571, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI22026922, Length=328, Percent_Identity=23.1707317073171, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281362270, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45551945, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648969, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_EDWI9 (C5BC33)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002935174.1
- ProteinModelPortal:   C5BC33
- GeneID:   7959861
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3815
- OMA:   IDISTHK
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35870; Mature: 35739

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 195-195 BINDING 110-110 BINDING 110-110 BINDING 143-143 BINDING 259-259 BINDING 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPVASMAVIGAGSYGTALAITLARNGHPVVLWGHDPAHIAALEAARCNQAFLPDVRFP
CCCCCCHHHEEECCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
DTLSLESDLSRTLSASRDVLVVVPSHVFGDVLRQLRPHLRPDARLVWATKGLEAETGRLL
CCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
QDVACEALGPDIPLAVISGPTFAKELAAGLPTAIAVASQDAAFAEVLQQLLHCGKSFRVY
HHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
RNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGVALGADPATF
ECCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGMGVDEAQVQIGQVVEGYRNTKEVMSLAQRY
HHHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHC
GVEMPITEQIYQVLYCHKDVREAALSLLGRASRDENAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTPVASMAVIGAGSYGTALAITLARNGHPVVLWGHDPAHIAALEAARCNQAFLPDVRFP
CCCCCHHHEEECCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
DTLSLESDLSRTLSASRDVLVVVPSHVFGDVLRQLRPHLRPDARLVWATKGLEAETGRLL
CCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
QDVACEALGPDIPLAVISGPTFAKELAAGLPTAIAVASQDAAFAEVLQQLLHCGKSFRVY
HHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
RNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGVALGADPATF
ECCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGMGVDEAQVQIGQVVEGYRNTKEVMSLAQRY
HHHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHC
GVEMPITEQIYQVLYCHKDVREAALSLLGRASRDENAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA