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The map label for this gene is tpiA [H]

Identifier: 238921630

GI number: 238921630

Start: 3666465

End: 3667229

Strand: Reverse

Name: tpiA [H]

Synonym: NT01EI_3785

Alternate gene names: 238921630

Gene position: 3667229-3666465 (Counterclockwise)

Preceding gene: 238921631

Following gene: 238921628

Centisome position: 96.19

GC content: 56.6

Gene sequence:

>765_bases
ATGCGTCAACCATTAGTTATGGGTAACTGGAAACTGAACGGTAGCCGCCACATGGTTCATGAACTGGTTGCCGCCCTGCG
CGGTGAACTGAGCGACGTTGCAAACTGCGATGTCGCCATCGCTCCGCCGGCAGTTTATCTGGATATGGCCGCCCATGAAC
TGGCCGGTAGCCGTATTGCCCTCGGTGCCCAGGACGTCAGTATCAATGCCTCCGGCGCATTCACCGGAGAAATCTCCGCA
GCGATGCTGAAAGACATCGGTGCAAAATACATCATCATTGGTCACTCCGAGCGCCGTACCTACCACAAAGAAGGCGACGC
GTTCATCGCAGAAAAATTTGCCGCACTGAAAGAAGCCGGTCTGATCCCGGTGCTGTGCATCGGTGAGACTGAAGCCGAAA
ACGAAGCAGGTAAAACGGAAGAAGTCTGCGCCCGCCAGCTGGATGCCGTACTGAAAACCATGGGTGCTCAGGTGTTTAAA
GGCGCCGTTATCGCCTATGAACCGGTATGGGCCATCGGCACCGGAAAATCTGCCACTCCGGAACAGGCTCAGGCTGTACA
CAAATTTATCCGCGATCACGTTGCCCAGCACGACGCTGAAGCCGCGCAGGAAGTCATTATCCAGTACGGCGGTTCTGTCA
ACGCAGCCAATGCGGCCGATCTGTTCAAGCAGCCGGATATCGACGGTGCACTGGTCGGCGGGGCCTCACTGAAGGCCGAT
GCGTTCGCCACCATCGTACGCGCCGCTGCCGCATATAAAGCTTAA

Upstream 100 bases:

>100_bases
AACAAAGTGCCTGACACCCAAGATTTTTATACTGTCAGACAGAATATGCCGACAAGGCGAGTTGATTTCGATTATGTGTT
TCCCAATTGGAGGAAAGAAA

Downstream 100 bases:

>100_bases
GCGCCGCTCAGCCAGCGCCGAATGCAACGGCTCCCGATGGGAGCCGTTTTTTATTTGGCATCGCCCACGCCCAGCGCATA
AAAAATTGACCCTGCTCCAT

Product: triose-phosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRQPLVMGNWKLNGSRHMVHELVAALRGELSDVANCDVAIAPPAVYLDMAAHELAGSRIALGAQDVSINASGAFTGEISA
AMLKDIGAKYIIIGHSERRTYHKEGDAFIAEKFAALKEAGLIPVLCIGETEAENEAGKTEEVCARQLDAVLKTMGAQVFK
GAVIAYEPVWAIGTGKSATPEQAQAVHKFIRDHVAQHDAEAAQEVIIQYGGSVNAANAADLFKQPDIDGALVGGASLKAD
AFATIVRAAAAYKA

Sequences:

>Translated_254_residues
MRQPLVMGNWKLNGSRHMVHELVAALRGELSDVANCDVAIAPPAVYLDMAAHELAGSRIALGAQDVSINASGAFTGEISA
AMLKDIGAKYIIIGHSERRTYHKEGDAFIAEKFAALKEAGLIPVLCIGETEAENEAGKTEEVCARQLDAVLKTMGAQVFK
GAVIAYEPVWAIGTGKSATPEQAQAVHKFIRDHVAQHDAEAAQEVIIQYGGSVNAANAADLFKQPDIDGALVGGASLKAD
AFATIVRAAAAYKA
>Mature_254_residues
MRQPLVMGNWKLNGSRHMVHELVAALRGELSDVANCDVAIAPPAVYLDMAAHELAGSRIALGAQDVSINASGAFTGEISA
AMLKDIGAKYIIIGHSERRTYHKEGDAFIAEKFAALKEAGLIPVLCIGETEAENEAGKTEEVCARQLDAVLKTMGAQVFK
GAVIAYEPVWAIGTGKSATPEQAQAVHKFIRDHVAQHDAEAAQEVIIQYGGSVNAANAADLFKQPDIDGALVGGASLKAD
AFATIVRAAAAYKA

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=248, Percent_Identity=44.758064516129, Blast_Score=193, Evalue=1e-49,
Organism=Homo sapiens, GI226529917, Length=248, Percent_Identity=44.758064516129, Blast_Score=193, Evalue=2e-49,
Organism=Escherichia coli, GI1790353, Length=253, Percent_Identity=80.2371541501976, Blast_Score=414, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17536593, Length=248, Percent_Identity=49.5967741935484, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320255, Length=248, Percent_Identity=47.5806451612903, Blast_Score=211, Evalue=6e-56,
Organism=Drosophila melanogaster, GI28572008, Length=248, Percent_Identity=50.8064516129032, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28572006, Length=248, Percent_Identity=50.8064516129032, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28572004, Length=248, Percent_Identity=50.8064516129032, Blast_Score=219, Evalue=1e-57,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 26707; Mature: 26707

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQPLVMGNWKLNGSRHMVHELVAALRGELSDVANCDVAIAPPAVYLDMAAHELAGSRIA
CCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCEEE
LGAQDVSINASGAFTGEISAAMLKDIGAKYIIIGHSERRTYHKEGDAFIAEKFAALKEAG
ECCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHCCCCHHHHHHHHHHHHCC
LIPVLCIGETEAENEAGKTEEVCARQLDAVLKTMGAQVFKGAVIAYEPVWAIGTGKSATP
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCH
EQAQAVHKFIRDHVAQHDAEAAQEVIIQYGGSVNAANAADLFKQPDIDGALVGGASLKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEECCCCCCHH
AFATIVRAAAAYKA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRQPLVMGNWKLNGSRHMVHELVAALRGELSDVANCDVAIAPPAVYLDMAAHELAGSRIA
CCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCEEE
LGAQDVSINASGAFTGEISAAMLKDIGAKYIIIGHSERRTYHKEGDAFIAEKFAALKEAG
ECCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHCCCCHHHHHHHHHHHHCC
LIPVLCIGETEAENEAGKTEEVCARQLDAVLKTMGAQVFKGAVIAYEPVWAIGTGKSATP
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCH
EQAQAVHKFIRDHVAQHDAEAAQEVIIQYGGSVNAANAADLFKQPDIDGALVGGASLKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEECCCCCCHH
AFATIVRAAAAYKA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA