Click here to switch to the map view.

The map label for this gene is fdoG [H]

Identifier: 238921561

GI number: 238921561

Start: 3598605

End: 3599126

Strand: Direct

Name: fdoG [H]

Synonym: NT01EI_3713

Alternate gene names: 238921561

Gene position: 3598605-3599126 (Clockwise)

Preceding gene: 238921558

Following gene: 238921562

Centisome position: 94.39

GC content: 59.58

Gene sequence:

>522_bases
GTGCTGGGCTTCGCCCCGTCGCTGGCTTTGGCACAAACCCGGCAGTACAAGCTACTGCGCGCCAAAGAAACCCGTAATAC
CTGTACATACTGTTCCGTGGGCTGTGGGCTGTTGATGTACAGCCTGGGGGATGGAGCCAAAAACGCAAAGGAGAGTATTT
TTCATATCGAAGGGGATCCGGATCATCCAGTAAACCGCGGCGCGCTGTGTCCGAAGGGCGCCGGTCTCATCGATTTTATC
CACAGTGAATCCCGGCTGCAGTATCCGGAATACCGCGCACCCGGCTCCAACGTCTGGCAGCGCCTCAGCTGGGATGAGGC
CTTTACCCGCATCGCCCGCCTGATCAAACAGGACCGCGATGCCCACTTTATCGCCACCAACGCCCAGGGCGTCACCGTCA
ACCGCTGGCTGAGTACCGGGATGCTGTGCGCCTCGGCCTCCAGCAACGAAACCGGCTATCTGACCCAAAAGTTCAGCCGG
GCGCTGGGGATGCTGGCAGTCGATAACCAAGCACGTGTCTGA

Upstream 100 bases:

>100_bases
TCAACAAACAATGTGGTTATTTGAGGAGCAATCCATGCAAGTCAGCAGAAGACAATTCTTCAGGATCTGCGCTGGCGGTA
TGGCAGGAACAACGGCAGCA

Downstream 100 bases:

>100_bases
CACGGACCAACGGTAGCAAGTCTTGCTCCAACATTTGGTCGCGGTGCCATGACCAACCACTGGGTCGACATCAAGAACGC
CAACCTGATAGTGGTGATGG

Product: formate dehydrogenase, alpha subunit

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MLGFAPSLALAQTRQYKLLRAKETRNTCTYCSVGCGLLMYSLGDGAKNAKESIFHIEGDPDHPVNRGALCPKGAGLIDFI
HSESRLQYPEYRAPGSNVWQRLSWDEAFTRIARLIKQDRDAHFIATNAQGVTVNRWLSTGMLCASASSNETGYLTQKFSR
ALGMLAVDNQARV

Sequences:

>Translated_173_residues
MLGFAPSLALAQTRQYKLLRAKETRNTCTYCSVGCGLLMYSLGDGAKNAKESIFHIEGDPDHPVNRGALCPKGAGLIDFI
HSESRLQYPEYRAPGSNVWQRLSWDEAFTRIARLIKQDRDAHFIATNAQGVTVNRWLSTGMLCASASSNETGYLTQKFSR
ALGMLAVDNQARV
>Mature_173_residues
MLGFAPSLALAQTRQYKLLRAKETRNTCTYCSVGCGLLMYSLGDGAKNAKESIFHIEGDPDHPVNRGALCPKGAGLIDFI
HSESRLQYPEYRAPGSNVWQRLSWDEAFTRIARLIKQDRDAHFIATNAQGVTVNRWLSTGMLCASASSNETGYLTQKFSR
ALGMLAVDNQARV

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=172, Percent_Identity=87.7906976744186, Blast_Score=329, Evalue=7e-92,
Organism=Escherichia coli, GI3868719, Length=172, Percent_Identity=81.3953488372093, Blast_Score=308, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 19116; Mature: 19116

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGFAPSLALAQTRQYKLLRAKETRNTCTYCSVGCGLLMYSLGDGAKNAKESIFHIEGDP
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
DHPVNRGALCPKGAGLIDFIHSESRLQYPEYRAPGSNVWQRLSWDEAFTRIARLIKQDRD
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
AHFIATNAQGVTVNRWLSTGMLCASASSNETGYLTQKFSRALGMLAVDNQARV
CEEEEECCCCEEHHHHHHHCEEEECCCCCCCCHHHHHHHHHHCEEEECCCCCC
>Mature Secondary Structure
MLGFAPSLALAQTRQYKLLRAKETRNTCTYCSVGCGLLMYSLGDGAKNAKESIFHIEGDP
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
DHPVNRGALCPKGAGLIDFIHSESRLQYPEYRAPGSNVWQRLSWDEAFTRIARLIKQDRD
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
AHFIATNAQGVTVNRWLSTGMLCASASSNETGYLTQKFSRALGMLAVDNQARV
CEEEEECCCCEEHHHHHHHCEEEECCCCCCCCHHHHHHHHHHCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]