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The map label for this gene is trkA [H]

Identifier: 238921412

GI number: 238921412

Start: 3465131

End: 3466507

Strand: Direct

Name: trkA [H]

Synonym: NT01EI_3563

Alternate gene names: 238921412

Gene position: 3465131-3466507 (Clockwise)

Preceding gene: 238921411

Following gene: 238921413

Centisome position: 90.89

GC content: 58.24

Gene sequence:

>1377_bases
ATGAAAATTATCATTTTAGGTGCCGGCCAGGTGGGGGGTACCCTAGCGGAAAACCTGGTAGGTGAGAATAACGATATCAC
CATCGTCGACACCAACAGCGATCGTCTGCGTCAACTACAAGATAAGTTCGATCTGCGCGTCGTGCAGGGCTATGGTTCCC
ATCCGCGGGTACTACGTGAAGCCGGTGCGGACGACGCCGATATGCTGGTCGCCGTGACCAGCTCGGACGAAACCAACATG
ATCGCCTGCCAGGTCGCCTATTCCCTGTTCAGCACCCCAAACCGGATCGCCCGCATCCGCTCGACCGAATATATCCGCGA
ACACGAGCGGTTGTTCAACCCAGAGGCGGTTCCCATCGATCACCTGATTGCACCCGAACAGCTGGTCACCGACTATGTCT
ACCGGCTAATCGAATATCCCGGGGCGCTGCAGGTGGTGAACTTTGCCGGGGGTAAGGTCAGCCTGGTGGCGGTCAAAGCC
TATTACGGCGGGCCGTTGGTGGGCAATGCCCTGACCTCGCTGAAGGAGCATATGCCGCATATCGATACGCGCGTGGCGGC
GATCTTCCGTCAGGATCGGCCGATCCGTCCGCAGGGGTCCACGGTGATCGAGGCCGGCGACGAGGTTTTCTTTGTCGCGG
CATCGCATAACATCCGGGCGGTAATGAGTGAGCTGCAACGGCTGGAGAAACCCTATAAACGTATCATGATCGTCGGCGGC
GGCAACGTCGGCGCCGGGCTGGCCCAGCGACTGGAGAAAGACTACAGTGTCAAGCTGATTGAGCATAACGCCCAGCGCGC
GGCCGAGCTGGCCGAGAAGTTGCATGACACCATCGTCTTTTACGGCGATGCCTCCGATCAGGAGTTGCTGACTGAAGAGC
ACATCGACCAGGTGGATGTTTTCATCGCCCTAACCAACGATGATGAGGCCAATATTATGTCGGCCATGCTAGCCAAGCGC
CTCGGCGCCAAAAAGGTGATGGTGCTGATTCAGCGCAGCGCCTACGTCGATCTGGTACAGGGCAGCGTCATCGATATCGC
CATCTCACCGCAGCAGGCCACCATTTCCGCTCTGCTCGGCCATGTGCGCAAGGCGGATATCGTTAGCGTCTCCTCCCTGC
GACGCGGCGTGGCGGAGGCGATTGAAGCCATCGCGCACGGCGACGAAAGCACCTCGAAGGTGGTCGGACGGCGAGTAGAG
GAGATTAAGCTGCCGCCAGGCACCACCATCGGTGCCATCGTACGGGGGGACGACGTGCTGATTGCCAGCCGTGAGTCCAA
AATTGAACAGGGAGATCACGTGATCATGTTCCTGACGGACAAGAAATTTATATCCGACGTGGAGCGCCTGTTTCAGCCAA
GTCCTTTCTTTTTGTAA

Upstream 100 bases:

>100_bases
CCCGACGCGGGCGACGGCTTCTTTTACACTAAGCTGATAAAAGCGTAATCCGCAGGCCGCCCGCCAGGCGGTCGGCGCTC
GCCAAGCAGAGAACAGCATC

Downstream 100 bases:

>100_bases
CTACAGCTATGCTCAACTATCGCTCCGTGCTGTACATCCTTGGGATGATGCTATCCAAAGTGGCGCTGCTGATGTACGTG
CCGCTGCTGTATGCCCTGCT

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIIILGAGQVGGTLAENLVGENNDITIVDTNSDRLRQLQDKFDLRVVQGYGSHPRVLREAGADDADMLVAVTSSDETNM
IACQVAYSLFSTPNRIARIRSTEYIREHERLFNPEAVPIDHLIAPEQLVTDYVYRLIEYPGALQVVNFAGGKVSLVAVKA
YYGGPLVGNALTSLKEHMPHIDTRVAAIFRQDRPIRPQGSTVIEAGDEVFFVAASHNIRAVMSELQRLEKPYKRIMIVGG
GNVGAGLAQRLEKDYSVKLIEHNAQRAAELAEKLHDTIVFYGDASDQELLTEEHIDQVDVFIALTNDDEANIMSAMLAKR
LGAKKVMVLIQRSAYVDLVQGSVIDIAISPQQATISALLGHVRKADIVSVSSLRRGVAEAIEAIAHGDESTSKVVGRRVE
EIKLPPGTTIGAIVRGDDVLIASRESKIEQGDHVIMFLTDKKFISDVERLFQPSPFFL

Sequences:

>Translated_458_residues
MKIIILGAGQVGGTLAENLVGENNDITIVDTNSDRLRQLQDKFDLRVVQGYGSHPRVLREAGADDADMLVAVTSSDETNM
IACQVAYSLFSTPNRIARIRSTEYIREHERLFNPEAVPIDHLIAPEQLVTDYVYRLIEYPGALQVVNFAGGKVSLVAVKA
YYGGPLVGNALTSLKEHMPHIDTRVAAIFRQDRPIRPQGSTVIEAGDEVFFVAASHNIRAVMSELQRLEKPYKRIMIVGG
GNVGAGLAQRLEKDYSVKLIEHNAQRAAELAEKLHDTIVFYGDASDQELLTEEHIDQVDVFIALTNDDEANIMSAMLAKR
LGAKKVMVLIQRSAYVDLVQGSVIDIAISPQQATISALLGHVRKADIVSVSSLRRGVAEAIEAIAHGDESTSKVVGRRVE
EIKLPPGTTIGAIVRGDDVLIASRESKIEQGDHVIMFLTDKKFISDVERLFQPSPFFL
>Mature_458_residues
MKIIILGAGQVGGTLAENLVGENNDITIVDTNSDRLRQLQDKFDLRVVQGYGSHPRVLREAGADDADMLVAVTSSDETNM
IACQVAYSLFSTPNRIARIRSTEYIREHERLFNPEAVPIDHLIAPEQLVTDYVYRLIEYPGALQVVNFAGGKVSLVAVKA
YYGGPLVGNALTSLKEHMPHIDTRVAAIFRQDRPIRPQGSTVIEAGDEVFFVAASHNIRAVMSELQRLEKPYKRIMIVGG
GNVGAGLAQRLEKDYSVKLIEHNAQRAAELAEKLHDTIVFYGDASDQELLTEEHIDQVDVFIALTNDDEANIMSAMLAKR
LGAKKVMVLIQRSAYVDLVQGSVIDIAISPQQATISALLGHVRKADIVSVSSLRRGVAEAIEAIAHGDESTSKVVGRRVE
EIKLPPGTTIGAIVRGDDVLIASRESKIEQGDHVIMFLTDKKFISDVERLFQPSPFFL

Specific function: Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=86.0262008733624, Blast_Score=818, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50287; Mature: 50287

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGGTLAENLVGENNDITIVDTNSDRLRQLQDKFDLRVVQGYGSHPRVLRE
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCEEEEECCCCCCHHHHH
AGADDADMLVAVTSSDETNMIACQVAYSLFSTPNRIARIRSTEYIREHERLFNPEAVPID
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
HLIAPEQLVTDYVYRLIEYPGALQVVNFAGGKVSLVAVKAYYGGPLVGNALTSLKEHMPH
HHCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHCCC
IDTRVAAIFRQDRPIRPQGSTVIEAGDEVFFVAASHNIRAVMSELQRLEKPYKRIMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHCHHHEEEEEEC
GNVGAGLAQRLEKDYSVKLIEHNAQRAAELAEKLHDTIVFYGDASDQELLTEEHIDQVDV
CCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCEEEE
FIALTNDDEANIMSAMLAKRLGAKKVMVLIQRSAYVDLVQGSVIDIAISPQQATISALLG
EEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHH
HVRKADIVSVSSLRRGVAEAIEAIAHGDESTSKVVGRRVEEIKLPPGTTIGAIVRGDDVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCEEEEEECCEEE
IASRESKIEQGDHVIMFLTDKKFISDVERLFQPSPFFL
EECCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIIILGAGQVGGTLAENLVGENNDITIVDTNSDRLRQLQDKFDLRVVQGYGSHPRVLRE
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCEEEEECCCCCCHHHHH
AGADDADMLVAVTSSDETNMIACQVAYSLFSTPNRIARIRSTEYIREHERLFNPEAVPID
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
HLIAPEQLVTDYVYRLIEYPGALQVVNFAGGKVSLVAVKAYYGGPLVGNALTSLKEHMPH
HHCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHCCC
IDTRVAAIFRQDRPIRPQGSTVIEAGDEVFFVAASHNIRAVMSELQRLEKPYKRIMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHCHHHEEEEEEC
GNVGAGLAQRLEKDYSVKLIEHNAQRAAELAEKLHDTIVFYGDASDQELLTEEHIDQVDV
CCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCEEEE
FIALTNDDEANIMSAMLAKRLGAKKVMVLIQRSAYVDLVQGSVIDIAISPQQATISALLG
EEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHH
HVRKADIVSVSSLRRGVAEAIEAIAHGDESTSKVVGRRVEEIKLPPGTTIGAIVRGDDVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCEEEEEECCEEE
IASRESKIEQGDHVIMFLTDKKFISDVERLFQPSPFFL
EECCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]