| Definition | Edwardsiella ictaluri 93-146 chromosome, complete genome. |
|---|---|
| Accession | NC_012779 |
| Length | 3,812,315 |
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The map label for this gene is relA [H]
Identifier: 238920898
GI number: 238920898
Start: 2911893
End: 2914139
Strand: Reverse
Name: relA [H]
Synonym: NT01EI_3025
Alternate gene names: 238920898
Gene position: 2914139-2911893 (Counterclockwise)
Preceding gene: 238920899
Following gene: 238920897
Centisome position: 76.44
GC content: 62.17
Gene sequence:
>2247_bases ATGGTCGCGGTAAGAAGTGCTCATTTGAATACGGCTGGTGAATTTGTCCCCGAGCAGTGGGTGGCAAGCCTGAACCTGTC CAATTCTGAGTCGTGTGAGCGTCTCACCGCCACCTGGCGCTATTGTCAGGAGAAGACCGCCGGTAACGCCGCGGCGCCGC TGCTGTTGTGGCGCGGCGTTGAAATGGTCGAGATCCTCTCTACCCTGAGCATGGATAATGACAGTATGCGCGCCGCGCTG CTGTTTCCGCTGGTGGATGGCGCGGTGATCGATGATGCCCGGGTGCGCGAGGACTTTGGTCTGGGCATCGCCGATCTGGT GCGCGGTGTGCTGGAGATGGACGCCATTCGTCAGCTGAAGGCTACCCAGGATGGGGCCGTCGGATCGGAGCAGGTGGACA ATATCCGCCGGATGCTGCTGGCTATCGTAGAGGACTTCCGCTGCGTGGTGATCAAGCTGGCGGAGCGCATTGCCCACCTG CGCGAGGTGAAGGATGCGCCGGAAGAGGAGCGCGTGCTGGCGGCCAAGGAGAGCTTCAATATCTATGCCCCGTTGGCCAA CCGTCTGGGGATCGGCCAGCTGAAGTGGGAGCTGGAGGACTTTTGCTTCCGCTACCTGCATCCGGAGGAGTATAAGCGCA TTGCCAAGCTGCTGCATGAGCGGCGCATCGACCGCGAGCAGTTTATCGATGACTTTGTGCGCGATCTGCGCAGGGCAATG GCCGAGGAGGGGATCAAGGCGGATATCTACGGTCGCCCCAAGCATATCTACAGCATCTGGCGCAAGATGCAGAAGAAGTC GTTGGCCTTTGACGAGTTGTTCGACGTGCGCGCGGTGCGGGTGGTGGTCGATCGCCTGCAGGACTGCTACGCGGCGCTGG GGATAGTGCATACTCACTACCGTCACCTGCCCAGCGAGTTCGATGACTACGTCGCTAACCCCAAGCCCAACGGCTACCAG TCGATCCATACGGTGGTGCTCGGGCCGCACGGCAAGACGCTGGAGATCCAGATCCGTACCCGCCAGATGCACGAGGATGC CGAGCTCGGCGTGGCGGCGCACTGGAAGTACAAAGAGGGGCCGCAGGCGGGCGGCCGCTCCGGCTACGATAACCGTATCG CCTGGCTGCGCAAGCTGCTGGCCTGGCAGGAGGAGATGGCCGACAGCGGCGAGATGATCGATGAGGTGAGAAGTCAGGTG CTGGACGATCGGGTGTATGTCTTTACCCCCAAAGGCGACGTTATCGATCTGCCCGCCGGCTCCACGCCCCTCGACTTTGC CTACCATATTCACAGCGACGTCGGCCACCGCTGTATCGGCGCCAAGATCGGCGGGCGGATCGTCCCCTTTACCTACCAGC TGCAGATGGGCGATCAGGTGGATATCATCACCCAGAAGCAGCCTAACCCGAGCCGTGACTGGCTGAATCCCAACCTGGGG TATGTCACCACCAGCCGCGGGCGCGCCAAGATCCACAATTGGTTCCGTAAGCTCGATCGCGATAAGAATATCCAGGCCGG GCGCCAGATCCTGGATGACGAGCTGGCCCGTCTGGGGATCAGCCTGAAAGAGGCGGAAAAGCTGCTGCTGCCGCGCTACA ACGTGCATACCCTGGACGAAGTGCTGGCCGCCATTGGCGGCGGCGATATCCGCCTGAACCAGATGGTCAACTTCCTGCAG GGCAAGATCAACAAGCCCAGCGCGGAGGAGGCCGATCGCGAGGCGCTGAAGCAGCTGACCCAGAAGGGGCAGTCCAGCGT GCGCAGCGACAAGAGCAGCGGCCGGGTGGTGGTCGAAGGGGTCGGTAACCTGATGCACCACATCGCCCGCTGCTGTCAGC CGATCCCCGGCGATGAGATCGTCGGTTTCATTACCCAGGGGCGCGGGATCTCCATTCATCGCGCCGACTGTGACCAGCTG GACGAGCTGCGCCGCCACGCGCCGGAGCGGATCATTGACGCGGTATGGGGTGAGAGCTACTCCAGCGGCTATTCGCTGGT GGTGCGGGTGACCGCCAACGATCGCAGCGGGCTGCTGCGCGACATCACCACCATTCTGGCCAACGAAAAGGTCAATGTGT TGGGGGTTGCCAGCCGCAGCGACACCAGGCAGCAGATGGCGACTATCGATATGGAGATAGAGATCTATAACCTGCAGGTG CTGGGTCGGGTGCTGGCCAAGCTGAATCAGCTGCCGGACGTGCTGGATGCGCGTCGTCTGAACGGCGGACGCGGCGGCGC GGAGTAA
Upstream 100 bases:
>100_bases TGGACATGTTTCCCCACACGGGGCATTTGGAGTCGATGGCGCTGTTTGAATCTGCGGCGCAATAGGCATTTGATAGGCAG TAGTCGAGAGGGAGAGAACC
Downstream 100 bases:
>100_bases GCACGGGGCCTCCTGACCACGATCTGAAGCGCCGACCCGGGTAGGGGCGGCAGGCGTCGCGTGCGGCGCCCCATTTTTCT GTTGGAATAACATCGATGAC
Product: GDP/GTP pyrophosphokinase
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 748; Mature: 748
Protein sequence:
>748_residues MVAVRSAHLNTAGEFVPEQWVASLNLSNSESCERLTATWRYCQEKTAGNAAAPLLLWRGVEMVEILSTLSMDNDSMRAAL LFPLVDGAVIDDARVREDFGLGIADLVRGVLEMDAIRQLKATQDGAVGSEQVDNIRRMLLAIVEDFRCVVIKLAERIAHL REVKDAPEEERVLAAKESFNIYAPLANRLGIGQLKWELEDFCFRYLHPEEYKRIAKLLHERRIDREQFIDDFVRDLRRAM AEEGIKADIYGRPKHIYSIWRKMQKKSLAFDELFDVRAVRVVVDRLQDCYAALGIVHTHYRHLPSEFDDYVANPKPNGYQ SIHTVVLGPHGKTLEIQIRTRQMHEDAELGVAAHWKYKEGPQAGGRSGYDNRIAWLRKLLAWQEEMADSGEMIDEVRSQV LDDRVYVFTPKGDVIDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQVDIITQKQPNPSRDWLNPNLG YVTTSRGRAKIHNWFRKLDRDKNIQAGRQILDDELARLGISLKEAEKLLLPRYNVHTLDEVLAAIGGGDIRLNQMVNFLQ GKINKPSAEEADREALKQLTQKGQSSVRSDKSSGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISIHRADCDQL DELRRHAPERIIDAVWGESYSSGYSLVVRVTANDRSGLLRDITTILANEKVNVLGVASRSDTRQQMATIDMEIEIYNLQV LGRVLAKLNQLPDVLDARRLNGGRGGAE
Sequences:
>Translated_748_residues MVAVRSAHLNTAGEFVPEQWVASLNLSNSESCERLTATWRYCQEKTAGNAAAPLLLWRGVEMVEILSTLSMDNDSMRAAL LFPLVDGAVIDDARVREDFGLGIADLVRGVLEMDAIRQLKATQDGAVGSEQVDNIRRMLLAIVEDFRCVVIKLAERIAHL REVKDAPEEERVLAAKESFNIYAPLANRLGIGQLKWELEDFCFRYLHPEEYKRIAKLLHERRIDREQFIDDFVRDLRRAM AEEGIKADIYGRPKHIYSIWRKMQKKSLAFDELFDVRAVRVVVDRLQDCYAALGIVHTHYRHLPSEFDDYVANPKPNGYQ SIHTVVLGPHGKTLEIQIRTRQMHEDAELGVAAHWKYKEGPQAGGRSGYDNRIAWLRKLLAWQEEMADSGEMIDEVRSQV LDDRVYVFTPKGDVIDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQVDIITQKQPNPSRDWLNPNLG YVTTSRGRAKIHNWFRKLDRDKNIQAGRQILDDELARLGISLKEAEKLLLPRYNVHTLDEVLAAIGGGDIRLNQMVNFLQ GKINKPSAEEADREALKQLTQKGQSSVRSDKSSGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISIHRADCDQL DELRRHAPERIIDAVWGESYSSGYSLVVRVTANDRSGLLRDITTILANEKVNVLGVASRSDTRQQMATIDMEIEIYNLQV LGRVLAKLNQLPDVLDARRLNGGRGGAE >Mature_748_residues MVAVRSAHLNTAGEFVPEQWVASLNLSNSESCERLTATWRYCQEKTAGNAAAPLLLWRGVEMVEILSTLSMDNDSMRAAL LFPLVDGAVIDDARVREDFGLGIADLVRGVLEMDAIRQLKATQDGAVGSEQVDNIRRMLLAIVEDFRCVVIKLAERIAHL REVKDAPEEERVLAAKESFNIYAPLANRLGIGQLKWELEDFCFRYLHPEEYKRIAKLLHERRIDREQFIDDFVRDLRRAM AEEGIKADIYGRPKHIYSIWRKMQKKSLAFDELFDVRAVRVVVDRLQDCYAALGIVHTHYRHLPSEFDDYVANPKPNGYQ SIHTVVLGPHGKTLEIQIRTRQMHEDAELGVAAHWKYKEGPQAGGRSGYDNRIAWLRKLLAWQEEMADSGEMIDEVRSQV LDDRVYVFTPKGDVIDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQVDIITQKQPNPSRDWLNPNLG YVTTSRGRAKIHNWFRKLDRDKNIQAGRQILDDELARLGISLKEAEKLLLPRYNVHTLDEVLAAIGGGDIRLNQMVNFLQ GKINKPSAEEADREALKQLTQKGQSSVRSDKSSGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISIHRADCDQL DELRRHAPERIIDAVWGESYSSGYSLVVRVTANDRSGLLRDITTILANEKVNVLGVASRSDTRQQMATIDMEIEIYNLQV LGRVLAKLNQLPDVLDARRLNGGRGGAE
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ACT domain [H]
Homologues:
Organism=Escherichia coli, GI1789147, Length=744, Percent_Identity=81.4516129032258, Blast_Score=1259, Evalue=0.0, Organism=Escherichia coli, GI1790082, Length=680, Percent_Identity=32.3529411764706, Blast_Score=395, Evalue=1e-111,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 84364; Mature: 84364
Theoretical pI: Translated: 6.71; Mature: 6.71
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVAVRSAHLNTAGEFVPEQWVASLNLSNSESCERLTATWRYCQEKTAGNAAAPLLLWRGV CCEEECCCCCCHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCH EMVEILSTLSMDNDSMRAALLFPLVDGAVIDDARVREDFGLGIADLVRGVLEMDAIRQLK HHHHHHHHHCCCCCHHHHHHHHHHHCCCEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHH ATQDGAVGSEQVDNIRRMLLAIVEDFRCVVIKLAERIAHLREVKDAPEEERVLAAKESFN HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCE IYAPLANRLGIGQLKWELEDFCFRYLHPEEYKRIAKLLHERRIDREQFIDDFVRDLRRAM EEECHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH AEEGIKADIYGRPKHIYSIWRKMQKKSLAFDELFDVRAVRVVVDRLQDCYAALGIVHTHY HHCCCEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RHLPSEFDDYVANPKPNGYQSIHTVVLGPHGKTLEIQIRTRQMHEDAELGVAAHWKYKEG HHCCHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHHCCHHHCCEEEECCCCCC PQAGGRSGYDNRIAWLRKLLAWQEEMADSGEMIDEVRSQVLDDRVYVFTPKGDVIDLPAG CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCEEECCCC STPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQVDIITQKQPNPSRDWLNPNLG CCCCHHHHHHHHHHCCEEECCCCCCEEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCC YVTTSRGRAKIHNWFRKLDRDKNIQAGRQILDDELARLGISLKEAEKLLLPRYNVHTLDE EEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHH VLAAIGGGDIRLNQMVNFLQGKINKPSAEEADREALKQLTQKGQSSVRSDKSSGRVVVEG HHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHH VGNLMHHIARCCQPIPGDEIVGFITQGRGISIHRADCDQLDELRRHAPERIIDAVWGESY HHHHHHHHHHHCCCCCCCHHEEEEECCCCCEEECCCHHHHHHHHHHCHHHHHHHHHCCCC SSGYSLVVRVTANDRSGLLRDITTILANEKVNVLGVASRSDTRQQMATIDMEIEIYNLQV CCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHEEEEEEEEHHHH LGRVLAKLNQLPDVLDARRLNGGRGGAE HHHHHHHHHHCHHHHHHHHCCCCCCCCC >Mature Secondary Structure MVAVRSAHLNTAGEFVPEQWVASLNLSNSESCERLTATWRYCQEKTAGNAAAPLLLWRGV CCEEECCCCCCHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCH EMVEILSTLSMDNDSMRAALLFPLVDGAVIDDARVREDFGLGIADLVRGVLEMDAIRQLK HHHHHHHHHCCCCCHHHHHHHHHHHCCCEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHH ATQDGAVGSEQVDNIRRMLLAIVEDFRCVVIKLAERIAHLREVKDAPEEERVLAAKESFN HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCE IYAPLANRLGIGQLKWELEDFCFRYLHPEEYKRIAKLLHERRIDREQFIDDFVRDLRRAM EEECHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH AEEGIKADIYGRPKHIYSIWRKMQKKSLAFDELFDVRAVRVVVDRLQDCYAALGIVHTHY HHCCCEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RHLPSEFDDYVANPKPNGYQSIHTVVLGPHGKTLEIQIRTRQMHEDAELGVAAHWKYKEG HHCCHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHHCCHHHCCEEEECCCCCC PQAGGRSGYDNRIAWLRKLLAWQEEMADSGEMIDEVRSQVLDDRVYVFTPKGDVIDLPAG CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCEEECCCC STPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQVDIITQKQPNPSRDWLNPNLG CCCCHHHHHHHHHHCCEEECCCCCCEEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCC YVTTSRGRAKIHNWFRKLDRDKNIQAGRQILDDELARLGISLKEAEKLLLPRYNVHTLDE EEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHH VLAAIGGGDIRLNQMVNFLQGKINKPSAEEADREALKQLTQKGQSSVRSDKSSGRVVVEG HHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHH VGNLMHHIARCCQPIPGDEIVGFITQGRGISIHRADCDQLDELRRHAPERIIDAVWGESY HHHHHHHHHHHCCCCCCCHHEEEEECCCCCEEECCCHHHHHHHHHHCHHHHHHHHHCCCC SSGYSLVVRVTANDRSGLLRDITTILANEKVNVLGVASRSDTRQQMATIDMEIEIYNLQV CCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHEEEEEEEEHHHH LGRVLAKLNQLPDVLDARRLNGGRGGAE HHHHHHHHHHCHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]